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Fig. 6 | BMC Molecular and Cell Biology

Fig. 6

From: The DNA demethylation-regulated SFRP2 dictates the progression of endometriosis via activation of the Wnt/β-catenin signaling pathway

Fig. 6

SFRP2 was upregulated due to the reduced methylation status of the promoter. A Western blot analysis of SFRP2 protein level in EEECs under treatment of 5-Aza vs DMSO or in EEECs under transfection with DNMT1 shRNAs vs control group. Full-length blots/gels are presented in Supplementary Figure 1. B Western blot data of SFRP2 protein level. The protein expression levels of SFRP2 in EEECs treated with 5-Aza vs DMSO group. C Western blot data of SFRP2 protein level. The protein expression levels of SFRP2 in EEECs transfected with DNMT1 shRNAs vs control group. D Real-time RT PCR. The mRNA expression levels of SFRP2 in EEECs treated with 5-Aza vs control group. E Real-time RT PCR. The mRNA expression levels of SFRP2 in EEECs transfected with DNMT1 shRNAs vs control group. F MSP. The methylation rate of SFRP2 promoter in EEECs treated with 5-Aza vs DMSO group. G MSP. The methylation rate of SFRP2 promoter in EEECs transfected with DNMT1 shRNAs vs control group

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