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Table 2 GO analysis of the upregulation genes from the GSE135485 data

From: The DNA demethylation-regulated SFRP2 dictates the progression of endometriosis via activation of the Wnt/β-catenin signaling pathway

Category

Term

Count

PValue

GOTERM_BP_DIRECT

GO:0008584 ~ male gonad development

7

1.35E-07

GOTERM_MF_DIRECT

GO:0000980 ~ RNA polymerase II distal enhancer sequence-specific DNA binding

4

5.23E-04

GOTERM_BP_DIRECT

GO:0008585 ~ female gonad development

3

6.58E-04

GOTERM_MF_DIRECT

GO:0043565 ~ sequence-specific DNA binding

7

0.001463497

GOTERM_MF_DIRECT

GO:0001077 ~ transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding

5

0.002513506

GOTERM_BP_DIRECT

GO:0006366 ~ transcription from RNA polymerase II promoter

6

0.009651672

GOTERM_BP_DIRECT

GO:0045944 ~ positive regulation of transcription from RNA polymerase II promoter

8

0.01158106

GOTERM_MF_DIRECT

GO:0016491 ~ oxidoreductase activity

4

0.012548298

GOTERM_BP_DIRECT

GO:0007584 ~ response to nutrient

3

0.015396063

GOTERM_BP_DIRECT

GO:0050810 ~ regulation of steroid biosynthetic process

2

0.020307471

GOTERM_MF_DIRECT

GO:0047498 ~ calcium-dependent phospholipase A2 activity

2

0.021652815

GOTERM_BP_DIRECT

GO:0036149 ~ phosphatidylinositol acyl-chain remodeling

2

0.040211948

GOTERM_BP_DIRECT

GO:0036148 ~ phosphatidylglycerol acyl-chain remodeling

2

0.045126018

GOTERM_BP_DIRECT

GO:0036150 ~ phosphatidylserine acyl-chain remodeling

2

0.045126018

GOTERM_BP_DIRECT

GO:0036152 ~ phosphatidylethanolamine acyl-chain remodeling

2

0.059721243

GOTERM_BP_DIRECT

GO:0050482 ~ arachidonic acid secretion

2

0.059721243

GOTERM_MF_DIRECT

GO:0008270 ~ zinc ion binding

7

0.0613717

GOTERM_BP_DIRECT

GO:0036151 ~ phosphatidylcholine acyl-chain remodeling

2

0.066936914

GOTERM_MF_DIRECT

GO:0003682 ~ chromatin binding

4

0.068885928

GOTERM_BP_DIRECT

GO:0009755 ~ hormone-mediated signaling pathway

2

0.069330097

GOTERM_MF_DIRECT

GO:0004623 ~ phospholipase A2 activity

2

0.072674345

GOTERM_MF_DIRECT

GO:0017147 ~ Wnt-protein binding

2

0.072674345

GOTERM_BP_DIRECT

GO:0070374 ~ positive regulation of ERK1 and ERK2 cascade

3

0.073862462

GOTERM_CC_DIRECT

GO:0090575 ~ RNA polymerase II transcription factor complex

2

0.07673751

GOTERM_BP_DIRECT

GO:0050873 ~ brown fat cell differentiation

2

0.078843017

GOTERM_MF_DIRECT

GO:0003700 ~ transcription factor activity, sequence-specific DNA binding

6

0.081625912

GOTERM_MF_DIRECT

GO:0004879 ~ RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding

2

0.083902905

GOTERM_BP_DIRECT

GO:0006654 ~ phosphatidic acid biosynthetic process

2

0.085915314

GOTERM_CC_DIRECT

GO:0005576 ~ extracellular region

8

0.08929768

GOTERM_BP_DIRECT

GO:0035094 ~ response to nicotine

2

0.090600685

GOTERM_BP_DIRECT

GO:0030522 ~ intracellular receptor signaling pathway

2

0.092934565

GOTERM_BP_DIRECT

GO:0010811 ~ positive regulation of cell-substrate adhesion

2

0.092934565

GOTERM_BP_DIRECT

GO:0048468 ~ cell development

2

0.097584789

  1. The significant terms of GO enrichment analysis performed by DAVID from the GSE135485 data
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BMC Molecular and Cell Biology

ISSN: 2661-8850

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