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Fig. 2 | BMC Molecular and Cell Biology

Fig. 2

From: Cyclic tensile force modifies calvarial osteoblast function via the interplay between ERK1/2 and STAT3

Fig. 2

ERK1/2 and STAT3 were activated after mechanical tensile loading. (A) Densitometric analysis of ERK1/2, pERK1/2, STAT3, and pSTAT3 protein levels in osteoblasts under tensile loading for 6, 12, 24, and 48 h. (B) Representative images of ERK1/2, pERK1/2, STAT3, and pSTAT3 protein changes under tensile loading for 6, 12, 24, and 48 h. (C-D) Immunofluorescence assay showed nuclear translocation of ERK1/2 and STAT3 protein induced by tensile loading for 24 h. Scale bar: 25 μm, Bars represent mean ± SD. *p < 0.05, compared with the control group (0 h group)

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