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Fig. 5 | BMC Molecular and Cell Biology

Fig. 5

From: Computational analysis of missense variant CYP4F2*3 (V433M) in association with human CYP4F2 dysfunction: a functional and structural impact

Fig. 5

Secondary structure content in native CYP4F2 (A) and V433M variant (B) over 200 ns of the simulation period. PCA analysis plot of CYP4F2 in native (black) and V433M variant form (red) (C). The rmsf plot of eigenvector reveals V433M had higher fluctuation compared to native form (D). The Gibbs energy landscape plot during 200ns of simulation of native (E) and V433M variant form (F)

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