Computational analysis of missense variant CYP4F2*3 (V433M) in association with human CYP4F2 dysfunction: a functional and structural impact

Table 3 Pathogenicity evaluation of V433M variant on CYP4F2 protein by using bioinformatics tools

dbSNP ID	Amino acid change	PolyPhen-2		FATHMM-MKl		PANTHER-PSEP		CADD		PhD-SNP^g
		Prediction	Score	Prediction	Score	Prediction	Score	Prediction	Score	Prediction	Score
CYP4F2*3 (rs2108622)	V433M	Possibly damaging	1.0	AEFBHCI	0.754	Probably damaging	0.74	Deleterious	22.3	Pathogenic	0.865

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