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Cytoplasmic and organelle biology

Section edited by Andrew Peden

This section will consider submissions with a focus on the structure and function of the cellular organelles, cytoplasm and membrane trafficking.

  1. Content type: Research article

    The white coat colour of Yorkshire and Landrace pig breeds is caused by the dominant white I allele of KIT, associated with 450-kb duplications and a splice mutation (G > A) at the first base in intron 17. To tes...

    Authors: Ke Qin, Xinyu Liang, Guanjie Sun, Xuan Shi, Min Wang, Hongbo Liu, Yaosheng Chen, Xiaohong Liu and Zuyong He

    Citation: BMC Molecular and Cell Biology 2019 20:4

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  2. Content type: Research article

    Within the past years, umbilical cord (UC) and amniotic membrane (AM) expanded in human platelet lysate (PL) have been found to become increasingly candidate of mesenchymal stromal cells (MSCs) in preclinical ...

    Authors: Yongxu Mu, Xiaoyun Wu and Zhiming Hao

    Citation: BMC Cell Biology 2018 19:27

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  3. Content type: Research article

    KIF17, a kinesin-2 motor that functions in intraflagellar transport, can regulate the onset of photoreceptor outer segment development. However, the function of KIF17 in a mature photoreceptor remains unclear....

    Authors: Tylor R. Lewis, Sean R. Kundinger, Brian A. Link, Christine Insinna and Joseph C. Besharse

    Citation: BMC Cell Biology 2018 19:25

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  4. Content type: Research article

    Interactions of resident bacteria and/or their producing lipopolysaccharide (LPS) with sulcular epithelial keratinocytes may be regulated by autophagy in the gingival sulcus. In this study, we investigated an ...

    Authors: Kanako Hagio-Izaki, Madoka Yasunaga, Masahiro Yamaguchi, Hiroshi Kajiya, Hiromitsu Morita, Masahiro Yoneda, Takao Hirofuji and Jun Ohno

    Citation: BMC Cell Biology 2018 19:18

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  5. Content type: Research article

    In Drosophila early post-meiotic spermatids, mitochondria undergo dramatic shaping into the Nebenkern, a spherical body with complex internal structure that contains two interwrapped giant mitochondrial derivativ...

    Authors: Eric M. Sawyer, Elizabeth C. Brunner, Yihharn Hwang, Lauren E. Ivey, Olivia Brown, Megan Bannon, Dennis Akrobetu, Kelsey E. Sheaffer, Oshauna Morgan, Conroy O. Field, Nishita Suresh, M. Grace Gordon, E. Taylor Gunnell, Lindsay A. Regruto, Cricket G. Wood, Margaret T. Fuller…

    Citation: BMC Cell Biology 2017 18:16

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  6. Content type: Research article

    DNA hypermethylation is a key epigenetic mechanism for the silencing of many genes in cancer. Hinokitiol, a tropolone-related natural compound, is known to induce apoptosis and cell cycle arrest and has anti-i...

    Authors: Jung Seon Seo, Young Ha Choi, Ji Wook Moon, Hyeon Soo Kim and Sun-Hwa Park

    Citation: BMC Cell Biology 2017 18:14

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  7. Content type: Methodology article

    Imaging large volumes such as entire cells or small model organisms at nanoscale resolution seemed an unrealistic, rather tedious task so far. Now, technical advances have lead to several electron microscopy (...

    Authors: Irene Wacker, Waldemar Spomer, Andreas Hofmann, Marlene Thaler, Stefan Hillmer, Ulrich Gengenbach and Rasmus R. Schröder

    Citation: BMC Cell Biology 2016 17:38

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  8. Content type: Research article

    Mitochondrial dysfunction is one of the leading causes of neurological disorders in humans. Mitochondrial perturbations lead to adaptive mechanisms that include HIF-1 stabilization, though the consequences of ...

    Authors: Muntasir Kamal, Dayana R. D’Amora and Terrance J. Kubiseski

    Citation: BMC Cell Biology 2016 17:34

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  9. Content type: Research article

    Vacuolar-type proton pumps help maintain acid–base homeostasis either within intracellular compartments or at specialised plasma membranes. In mammals they are made up of 13 subunits, which form two functional...

    Authors: Zoe J. Golder and Fiona E. Karet Frankl

    Citation: BMC Cell Biology 2016 17:27

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  10. Content type: Research article

    Flagella and cilia are fine thread-like organelles protruding from cells that harbour them. The typical ‘9 + 2’ cilia confer motility on these cells. Although the mechanistic details of motility remain elusive...

    Authors: Venkatramanan G. Rao, Ruhi B. Sarafdar, Twinkle S. Chowdhury, Priyanka Sivadas, Pinfen Yang, Prabhakar M. Dongre and Jacinta S. D’Souza

    Citation: BMC Cell Biology 2016 17:24

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  11. Content type: Research article

    Seipin is required for the correct assembly of cytoplasmic lipid droplets. In the absence of the yeast seipin homolog Sei1p (formerly Fld1p), droplets are slow to bud from the endoplasmic reticulum, lack the n...

    Authors: Sungwon Han, Derk D. Binns, Yu-Fang Chang and Joel M. Goodman

    Citation: BMC Cell Biology 2015 16:29

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  12. Content type: Research article

    The membrane anchored kinase, LMTK2, is a serine/threonine kinase predominantly localized to endosomal compartments. LMTK2 has been shown to be involved in the trafficking of the CFTR ion channel, the androgen...

    Authors: E. C. Butler and Neil A. Bradbury

    Citation: BMC Cell Biology 2015 16:26

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  13. Content type: Research article

    Lipids are stored within cells in lipid droplets (LDs). They consist of a core of neutral lipids surrounded by a monolayer of phospholipids, predominantly phosphatidylcholine (PC). LDs are very dynamic and can...

    Authors: Christine Moessinger, Kristina Klizaite, Almut Steinhagen, Julia Philippou-Massier, Andrej Shevchenko, Michael Hoch, Christer S Ejsing and Christoph Thiele

    Citation: BMC Cell Biology 2014 15:43

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  14. Content type: Methodology article

    With the rapid advancement of cell biology, the evaluation of a given protein’s synthesis and release in cells becomes critical. However, up to now there has been no technique available to morphologically visu...

    Authors: Guowei Huang, Yun Wang, Juping Wang, Chunzhang Yang, Tao Huang, Zhengping Zhuang and Jiang Gu

    Citation: BMC Cell Biology 2014 15:45

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  15. Content type: Research article

    Neutrophils are a critical part of the innate immune system. Their ability to migrate into infected or injured tissues precedes their role in microbial killing and clearance. We have previously shown that Rab2...

    Authors: Rajesh K Singh, Rebecca C Furze, Mark A Birrell, Sara M Rankin, Alistair N Hume and Miguel C Seabra

    Citation: BMC Cell Biology 2014 15:39

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  16. Content type: Research article

    The expression of 2′-5′-Oligoadenylate synthetases (OASs) is induced by type 1 Interferons (IFNs) in response to viral infection. The OAS proteins have a unique ability to produce 2′-5′ Oligoadenylates, which ...

    Authors: Karina Hansen Kjær, Jytte Pahus, Mariann Fagernæs Hansen, Jesper Buchhave Poulsen, Erik Ilsø Christensen, Just Justesen and Pia Møller Martensen

    Citation: BMC Cell Biology 2014 15:33

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  17. Content type: Research article

    The Akita mutation (C96Y) in the insulin gene results in early onset diabetes in both humans and mice. Expression of mutant proinsulin (C96Y) causes endoplasmic reticulum (ER) stress in pancreatic β-cells and ...

    Authors: Liling Zhang, Courtney Nosak, Pietro Sollazzo, Tanya Odisho and Allen Volchuk

    Citation: BMC Cell Biology 2014 15:29

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  18. Content type: Review

    Live cell imaging enables the study of dynamic processes of living cells in real time by use of suitable reporter proteins and the staining of specific cellular structures and/or organelles. With the availabil...

    Authors: Sandeep Salipalli, Prafull Kumar Singh and Jürgen Borlak

    Citation: BMC Cell Biology 2014 15:26

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  19. Content type: Research article

    Clathrin-mediated vesicular trafficking, the mechanism by which proteins and lipids are transported between membrane-bound organelles, accounts for a large proportion of import from the plasma membrane (endocy...

    Authors: Ligia Cristina Kalb, Yohana Camila Antunes Frederico, Cassiano Martin Batista, Iriane Eger, Stênio Perdigão Fragoso and Maurilio José Soares

    Citation: BMC Cell Biology 2014 15:23

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  20. Content type: Research article

    Upon activation neutrophil releases microparticles - small plasma membrane vesicles that contain cell surface proteins and cytoplasmic matter, with biological activities. In this study we investigated the pote...

    Authors: Thassila Nogueira Pitanga, Luciana de Aragão França, Viviane Costa Junqueira Rocha, Thayna Meirelles, Valéria Matos Borges, Marilda Souza Gonçalves, Lain Carlos Pontes-de-Carvalho, Alberto Augusto Noronha-Dutra and Washington Luis Conrado dos-Santos

    Citation: BMC Cell Biology 2014 15:21

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  21. Content type: Research article

    Myosin IC is a single headed member of the myosin superfamily that localizes to the cytoplasm and the nucleus and is implicated in a variety of processes in both compartments. We recently identified a novel is...

    Authors: Neil L Sielski, Ivanna Ihnatovych, Jacob J Hagen and Wilma A Hofmann

    Citation: BMC Cell Biology 2014 15:8

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  22. Content type: Research article

    The Sec61 channel mediates protein translocation across the endoplasmic reticulum (ER) membrane during secretory protein biogenesis, and likely also during export of misfolded proteins for ER-associated degrad...

    Authors: Thomas Tretter, Fábio P Pereira, Ozlem Ulucan, Volkhard Helms, Susanne Allan, Kai-Uwe Kalies and Karin Römisch

    Citation: BMC Cell Biology 2013 14:56

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  23. Content type: Research article

    Acrosomal proteins play crucial roles in the physiology of fertilization. Identification of proteins localizing to the acrosome is fundamental to the understanding of its contribution to fertilization. Novel p...

    Authors: Rupa Bhattacharya, Manju S Devi, Vishnu M Dhople and Rachel A Jesudasan

    Citation: BMC Cell Biology 2013 14:50

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  24. Content type: Review

    The present review summarizes current knowledge about microparticles (MPs) and provides a systematic overview of last 20 years of research on circulating MPs, with particular focus on their clinical relevance.

    Authors: Natasha S Barteneva, Elizaveta Fasler-Kan, Michael Bernimoulin, Joel NH Stern, Eugeny D Ponomarev, Larry Duckett and Ivan A Vorobjev

    Citation: BMC Cell Biology 2013 14:23

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  25. Content type: Research article

    Previous studies have implicated continuous or intermittent hyperglycemia in altered endothelium-derived nitric oxide (NO) synthesis. NO can regulate both the F-actin cytoskeleton and endothelial cell membrane...

    Authors: Xianxian Chen, Lie Feng and Hua Jin

    Citation: BMC Cell Biology 2013 14:22

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  26. Content type: Methodology article

    The scarcity of certain nucleic acid species and the small size of target sequences such as miRNA, impose a significant barrier to subcellular visualization and present a major challenge to cell biologists. He...

    Authors: Kate L Jones, Adam Karpala, Bevan Hirst, Kristie Jenkins, Mark Tizard, Cândida F Pereira, Andrew Leis, Paul Monaghan, Alex Hyatt and Johnson Mak

    Citation: BMC Cell Biology 2013 14:21

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  27. Content type: Methodology article

    The kidney-specific NKCC cotransporter isoform NKCC2 is involved in the Na+ reabsorption in the Thich Ascending Limb (TAL) cells and in the regulation of body fluid volume. In contrast, the isoform NKCC1 represen...

    Authors: Monica Carmosino, Federica Rizzo, Silvia Torretta, Giuseppe Procino and Maria Svelto

    Citation: BMC Cell Biology 2013 14:16

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  28. Content type: Research article

    The regulatory mechanisms of motor protein-dependent intracellular transport are still not fully understood. The kinesin-1-binding protein, JIP1, can function as an adaptor protein that links kinesin-1 and oth...

    Authors: Tomoko Satake, Karin Otsuki, Yumi Banba, Jun Suenaga, Hisashi Hirano, Yuko Yamanaka, Shigeo Ohno and Syu-ichi Hirai

    Citation: BMC Cell Biology 2013 14:12

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  29. Content type: Research article

    Covalent modifications of proteins provide a mechanism to control protein function. Here, we have investigated modifications of the heptameric Sec complex which is responsible for post-translational protein im...

    Authors: Christina Soromani, Naiyan Zeng, Klaus Hollemeyer, Elmar Heinzle, Marie-Christine Klein, Thomas Tretter, Matthew N J Seaman and Karin Römisch

    Citation: BMC Cell Biology 2012 13:34

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2018 Journal Metrics

  • Citation Impact

    3.485 - 2-year Impact Factor
    3.227 - 5-year Impact Factor
    0.857 - Source Normalized Impact per Paper (SNIP)
    1.403 - SCImago Journal Rank (SJR)