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Membrane processes-transport

  1. Many cell permeabilisation methods to mediate internalisation of various molecules to mammalian or bacterial cells have been developed. However, no size-specific permeability assay suitable for both cell types...

    Authors: Yensi Flores Bueso, Sidney Walker, Jennifer Quinn and Mark Tangney

    Citation: BMC Molecular and Cell Biology 2020 21:75

    Content type: Methodology article

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  2. Endosomal trafficking and amyloidogenic cleavage of amyloid precursor protein (APP) is believed to play a role in the neurodegeneration observed in Alzheimer’s disease (AD). Recent evidence has suggested that ...

    Authors: Allaura S. Cone, Stephanie N. Hurwitz, Gloria S. Lee, Xuegang Yuan, Yi Zhou, Yan Li and David G. Meckes Jr

    Citation: BMC Molecular and Cell Biology 2020 21:58

    Content type: Research article

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  3. Type 2 diabetes mellitus (T2DM) is a worldwide disease that have an impact on individuals of all ages causing micro and macro vascular impairments due to hyperglycemic internal environment. For ultimate treatm...

    Authors: Syed Aun Muhammad, Hiba Ashfaq, Sidra Zafar, Fahad Munir, Muhammad Babar Jamshed, Jake Chen and Qiyu Zhang

    Citation: BMC Molecular and Cell Biology 2020 21:56

    Content type: Research article

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  4. Cytoprotection afforded by mitochondrial ATP-sensitive K+-channel (mKATP-channel) opener diazoxide (DZ) largely depends on the activation of potassium cycle with eventual modulation of mitochondrial functions and...

    Authors: Olga Akopova, Liudmila Kolchinskaya, Valentina Nosar, Iryna Mankovska and Vadim Sagach

    Citation: BMC Molecular and Cell Biology 2020 21:31

    Content type: Research article

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  5. Tartrate–resistant acid phosphatase (TRAP/ ACP5) belongs to the binuclear metallophosphatase family and is present in two isoforms. The primary translation product is an uncleaved TRAP 5a isoform with low phos...

    Authors: Anja Reithmeier, Maria Norgård, Barbro Ek-Rylander, Tuomas Näreoja and Göran Andersson

    Citation: BMC Molecular and Cell Biology 2020 21:15

    Content type: Research article

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  6. Interferon-alpha (IFNα) is a first-line treatment option for chronic hepatitis B virus (HBV) infection, but the severe systemic side-effects limited its clinical application. Interferon-lambda (IFNλ) with comp...

    Authors: Xiaoyan Guo, Dianke Chen, Qingxian Cai, Zhanlian Huang, Wenxiong Xu, Liang Peng and Ping Chen

    Citation: BMC Molecular and Cell Biology 2020 21:6

    Content type: Research article

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    The Correction to this article has been published in BMC Molecular and Cell Biology 2020 21:10

  7. All cells rely on lipids for key functions. Lipid transfer proteins allow lipids to exit the hydrophobic environment of bilayers, and cross aqueous spaces. One lipid transfer domain fold present in almost all ...

    Authors: Timothy P. Levine

    Citation: BMC Molecular and Cell Biology 2019 20:43

    Content type: Research article

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  8. CG4552/tbc1 was identified as a downstream target of Fork head (Fkh), the single Drosophila member of the FoxA family of transcription factors and a major player in salivary gland formation and homeostasis. Tbc1 ...

    Authors: Dorothy M. Johnson and Deborah J. Andrew

    Citation: BMC Molecular and Cell Biology 2019 20:19

    Content type: Research article

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  9. Colon cancer affects 1.23 million people worldwide and is the third most common malignant disease in men and the second in women. The only curative treatment is surgical resection, but a significant number of ...

    Authors: D. Yonar, A. Kılıç Süloğlu, G. Selmanoğlu and M. M. Sünnetçioğlu

    Citation: BMC Molecular and Cell Biology 2019 20:16

    Content type: Research article

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