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  1. Estrogens are reported to increase type I and type III collagen deposition and to regulate Metalloproteinase 2 (MMP-2) expression. These proteins are reported to be dysregulated in incisional hernia formation ...

    Authors: Petra Lynen Jansen, Raphael Rosch, Melanie Rezvani, Peter R Mertens, Karsten Junge, Marc Jansen and Uwe Klinge

    Citation: BMC Cell Biology 2006 7:36

    Content type: Research article

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  2. CtBP1 and CtBP2 are transcriptional co-repressors that modulate the activity of a large number of transcriptional repressors via the recruitment of chromatin modifiers. Many CtBP-regulated proteins are involve...

    Authors: Lee M Bergman, Laila Morris, Matthew Darley, Alexander H Mirnezami, Samal C Gunatilake and Jeremy P Blaydes

    Citation: BMC Cell Biology 2006 7:35

    Content type: Research article

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  3. HC11 mouse mammary epithelial cells differentiate in response to lactogenic hormone resulting in expression of milk proteins including β-casein. Previous studies have shown that epidermal growth factor (EGF) b...

    Authors: Traci Galbaugh, Maria Grazia Cerrito, Cynthia C Jose and Mary Lou Cutler

    Citation: BMC Cell Biology 2006 7:34

    Content type: Research article

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  4. The expression level of cyclin D1 plays a vital role in the control of proliferation. This protein is reported to be degraded following phosphorylation by glycogen synthase kinase 3 (GSK3) on Thr-286. We recen...

    Authors: Ke Yang, Yang Guo, William C Stacey, Jyoti Harwalkar, Jonathan Fretthold, Masahiro Hitomi and Dennis W Stacey

    Citation: BMC Cell Biology 2006 7:33

    Content type: Research article

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  5. DNA structure checkpoints are conserved eukaryotic signal transduction pathways that help preserve genomic integrity. Upon detecting checkpoint signals such as stalled replication forks or double-stranded DNA ...

    Authors: Erin E Baschal, Kuan J Chen, Lee G Elliott, Matthew J Herring, Shawn C Verde and Tom D Wolkow

    Citation: BMC Cell Biology 2006 7:32

    Content type: Research article

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  6. Transcription is regulated by a complex interaction of activators and repressors. The effectors of repression are large multimeric complexes which contain both the repressor proteins that bind to transcription...

    Authors: Xin-Min Zhang, Qing Chang, Lin Zeng, Judy Gu, Stuart Brown and Ross S Basch

    Citation: BMC Cell Biology 2006 7:31

    Content type: Research article

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  7. There is a growing interest in cord blood as a source of primitive stem cells with the capacity for multilineage differentiation. Pure cell fractions are needed for the characterization and in vitro expansion of ...

    Authors: Tuija Kekarainen, Sirkka Mannelin, Jarmo Laine and Taina Jaatinen

    Citation: BMC Cell Biology 2006 7:30

    Content type: Methodology article

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  8. Hyperplasia of usual type (HUT) is a common proliferative lesion associated with a slight elevated risk for subsequent development of breast cancer. Cell cycle-related proteins would be helpful to determine th...

    Authors: Luciene SA Tafuri, Gislene FS Rocha and Helenice Gobbi

    Citation: BMC Cell Biology 2006 7:29

    Content type: Research article

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  9. The Wnt signaling pathway regulates many processes during embryonic development, including axis specification, organogenesis, angiogenesis, and stem cell proliferation. Wnt signaling has also been implicated i...

    Authors: Jeremy T Blitzer and Roel Nusse

    Citation: BMC Cell Biology 2006 7:28

    Content type: Research article

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  10. The present study was carried out to determine whether the p53 pathway played a role in the spontaneous immortalization of the SC-2 chicken embryo fibroblast (CEF) cell line that has been in continuous culture...

    Authors: Shelly A Christman, Byung-Whi Kong, Megan M Landry, Hyunggee Kim and Douglas N Foster

    Citation: BMC Cell Biology 2006 7:27

    Content type: Research article

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  11. Studying mitosis requires a system in which the dramatic movements of chromosomes and spindle microtubules can be visualized. PtK cells, due to their flat morphology and their small number of large chromosomes...

    Authors: Jane R Stout, Rania S Rizk, Susan L Kline and Claire E Walczak

    Citation: BMC Cell Biology 2006 7:26

    Content type: Research article

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  12. Single-cell level studies are being used increasingly to measure cell properties not directly observable in a cell population. High-performance data acquisition systems for such studies have, by necessity, dev...

    Authors: Kiyoshi Ohnuma, Tetsuya Yomo, Makoto Asashima and Kunihiko Kaneko

    Citation: BMC Cell Biology 2006 7:25

    Content type: Methodology article

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  13. Integrins comprise a large family of α,β heterodimeric, transmembrane cell adhesion receptors that mediate diverse essential biological functions. Higher vertebrates possess a single β1 gene, and the β1 subuni...

    Authors: A Paul Mould, Jennifer A McLeish, Julie Huxley-Jones, Alexander C Goonesinghe, Adam FL Hurlstone, Raymond P Boot-Handford and Martin J Humphries

    Citation: BMC Cell Biology 2006 7:24

    Content type: Research article

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  14. There exists abundant molecular and ultra-structural evidence to suggest that cytoplasmic actin can physically interact with the nuclear envelope (NE) membrane system. However, this interaction has yet to be c...

    Authors: Sylvia Münter, Jost Enninga, Rafael Vazquez-Martinez, Erwan Delbarre, Brigitte David-Watine, Ulf Nehrbass and Spencer L Shorte

    Citation: BMC Cell Biology 2006 7:23

    Content type: Research article

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  15. The pim family genes encode oncogenic serine/threonine kinases which in hematopoietic cells have been implicated in cytokine-dependent signaling as well as in lymphomagenesis, especially in cooperation with other...

    Authors: Teija LT Aho, Jouko Sandholm, Katriina J Peltola, Yoshiaki Ito and Päivi J Koskinen

    Citation: BMC Cell Biology 2006 7:21

    Content type: Research article

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  16. The absorptive and goblet cells are the main cellular types encountered in the intestine epithelium. The cell lineage Caco-2 is a model commonly used to reproduce the features of the bowel epithelium. However,...

    Authors: Géraldine Nollevaux, Christelle Devillé, Benaïssa El Moualij, Willy Zorzi, Patricia Deloyer, Yves-Jacques Schneider, Olivier Peulen and Guy Dandrifosse

    Citation: BMC Cell Biology 2006 7:20

    Content type: Research article

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  17. Gene transcriptional activity is well correlated with intra-nuclear position, especially relative to the nuclear periphery, which is a region classically associated with gene silencing. Recently however, activ...

    Authors: David A Drubin, Arman M Garakani and Pamela A Silver

    Citation: BMC Cell Biology 2006 7:19

    Content type: Research article

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  18. Shroom is a recently-described regulator of cell shape changes in the developing nervous system. This protein is a member of a small family of related proteins that are defined by sequence similarity and in mo...

    Authors: Olivier Hagens, Andrea Ballabio, Vera Kalscheuer, Jean-Pierre Kraehenbuhl, M Vittoria Schiaffino, Peter Smith, Olivier Staub, Jeff Hildebrand and John B Wallingford

    Citation: BMC Cell Biology 2006 7:18

    Content type: Commentary

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  19. Thalidomide is an immunomodulatory agent, which arrests angiogenesis. The mechanism of anti-angiogenic activity of thalidomide is not fully understood. As nitric oxide is involved in angiogenesis, we speculate...

    Authors: KP Tamilarasan, Gopi Krishna Kolluru, Megha Rajaram, M Indhumathy, R Saranya and Suvro Chatterjee

    Citation: BMC Cell Biology 2006 7:17

    Content type: Research article

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  20. In endothelial cells (EC), transforming growth factor-β (TGF-β) can bind to and transduce signals through ALK1 and ALK5. The TGF-β/ALK5 and TGF-β/ALK1 pathways have opposite effects on EC behaviour. Besides di...

    Authors: Gudrun Valdimarsdottir, Marie-José Goumans, Fumiko Itoh, Susumu Itoh, Carl-Henrik Heldin and Peter ten Dijke

    Citation: BMC Cell Biology 2006 7:16

    Content type: Research article

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  21. Transforming Growth Factor-β (TGF-β) regulates key biological processes during development and in adult tissues and has been implicated in many diseases. To study the biological functions of TGF-β, sensitive, ...

    Authors: Ina Tesseur, Kun Zou, Elisabeth Berber, Hui Zhang and Tony Wyss-Coray

    Citation: BMC Cell Biology 2006 7:15

    Content type: Methodology article

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  22. A hot new topic in medical treatment is the use of mesenchymal stem cells (MSC) in therapy. The low frequency of this subpopulation of stem cells in bone marrow (BM) necessitates their in vitro expansion prior...

    Authors: Mandana Mohyeddin Bonab, Kamran Alimoghaddam, Fatemeh Talebian, Syed Hamid Ghaffari, Ardeshir Ghavamzadeh and Behrouz Nikbin

    Citation: BMC Cell Biology 2006 7:14

    Content type: Research article

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  23. Epithelial tight junction (TJ) and adherens junction (AJ) form the apical junctional complex (AJC) which regulates cell-cell adhesion, paracellular permeability and cell polarity. The AJC is anchored on cytosk...

    Authors: Andrei I Ivanov, Ingrid C McCall, Brian Babbin, Stanislav N Samarin, Asma Nusrat and Charles A Parkos

    Citation: BMC Cell Biology 2006 7:12

    Content type: Research article

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  24. Cell differentiation has long been theorized to represent a switch in a bistable system, and recent experimental work in micro-organisms has revealed bistable dynamics in small gene regulatory circuits. Howeve...

    Authors: Hannah H Chang, Philmo Y Oh, Donald E Ingber and Sui Huang

    Citation: BMC Cell Biology 2006 7:11

    Content type: Research article

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  25. Notch plays a wide-ranging role in controlling cell fate, differentiation and development. The PI3K-Akt pathway is a similarly conserved signalling pathway which regulates processes such as differentiation, pr...

    Authors: Grahame Mckenzie, George Ward, Yvette Stallwood, Emmanuel Briend, Sofia Papadia, Andrew Lennard, Martin Turner, Brian Champion and Giles E Hardingham

    Citation: BMC Cell Biology 2006 7:10

    Content type: Research article

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  26. The biochemical bases for hormone dependence in breast cancer have been recognized as an important element in tumor resistance, proliferation and metastasis. On this respect, dexamethasone (Dex) dependent prot...

    Authors: Catalina Machuca, Criselda Mendoza-Milla, Emilio Córdova, Salvador Mejía, Luis Covarrubias, José Ventura and Alejandro Zentella

    Citation: BMC Cell Biology 2006 7:9

    Content type: Research article

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  27. In human pancreatic cancer progression, the α6β1-integrin is expressed on cancer cell surface during invasion and metastasis formation. In this study, we investigated whether interleukin (IL)-1α induces the alter...

    Authors: Hirozumi Sawai, Yuji Okada, Hitoshi Funahashi, Yoichi Matsuo, Hiroki Takahashi, Hiromitsu Takeyama and Tadao Manabe

    Citation: BMC Cell Biology 2006 7:8

    Content type: Research article

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  28. The family of c-Jun NH2-terminal kinases (JNK) plays important roles in embryonic development and in cellular responses to stress. Toxic metals and their compounds are potent activators of JNK in mammalian cells....

    Authors: Olga P Ryabinina, Ezhilkani Subbian and Mihail S Iordanov

    Citation: BMC Cell Biology 2006 7:7

    Content type: Research article

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  29. Despite the great advances in the understanding of programmed cell death, little attention has been paid to the sequence of the events that characterise it. In particular, the course of apoptotic events induce...

    Authors: Francesco Fabbri, Silvia Carloni, Giovanni Brigliadori, Wainer Zoli, Rosa Lapalombella and Marina Marini

    Citation: BMC Cell Biology 2006 7:6

    Content type: Methodology article

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  30. Cutaneous wound repair in adult mammals does not regenerate the original epithelial architecture and results in altered skin function. We propose that lack of regeneration may be due to the absence of appropri...

    Authors: Carrie Fathke, Lynne Wilson, Kavita Shah, Brian Kim, Anne Hocking, Randall Moon and Frank Isik

    Citation: BMC Cell Biology 2006 7:4

    Content type: Research article

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  31. The trafficking of the adenomatous polyposis coli (APC) tumour suppressor protein in mammalian cells is a perennially controversial topic. Immunostaining evidence for an actin-associated APC localisation at in...

    Authors: Kelly J Langford, Jon M Askham, Tracy Lee, Matthew Adams and Ewan E Morrison

    Citation: BMC Cell Biology 2006 7:3

    Content type: Research article

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  32. Pim-1, 2 and 3 are a group of enzymes related to the calcium calmodulin family of protein kinases. Over-expression of Pim-1 and Pim-2 in mice promotes the development of lymphomas, and up-regulation of Pim exp...

    Authors: Andrew Macdonald, David G Campbell, Rachel Toth, Hilary McLauchlan, C James Hastie and J Simon C Arthur

    Citation: BMC Cell Biology 2006 7:1

    Content type: Research article

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  33. The soil nematode C. elegans survives oxygen-deprived conditions (anoxia; <.001 kPa O2) by entering into a state of suspended animation in which cell cycle progression reversibly arrests. The majority of blastome...

    Authors: Vinita A Hajeri, Jesus Trejo and Pamela A Padilla

    Citation: BMC Cell Biology 2005 6:47

    Content type: Research article

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  34. Copines are soluble, calcium-dependent membrane binding proteins found in a variety of organisms. Copines are characterized as having two C2 domains at the N-terminal region followed by an "A domain" at the C-...

    Authors: Cynthia K Damer, Marina Bayeva, Emily S Hahn, Javier Rivera and Catherine I Socec

    Citation: BMC Cell Biology 2005 6:46

    Content type: Research article

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  35. Cysteine-rich protein 1 (CRP1) is a LIM domain containing protein localized to the nucleus and the actin cytoskeleton. CRP1 has been demonstrated to bind the actin-bundling protein α-actinin and proposed to mo...

    Authors: Thuan C Tran, CoreyAyne Singleton, Tamara S Fraley and Jeffrey A Greenwood

    Citation: BMC Cell Biology 2005 6:45

    Content type: Research article

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  36. Similarities as well as differences in higher order chromatin arrangements of human cell types were previously reported. For an evolutionary comparison, we now studied the arrangements of chromosome territorie...

    Authors: Robert Mayer, Alessandro Brero, Johann von Hase, Timm Schroeder, Thomas Cremer and Steffen Dietzel

    Citation: BMC Cell Biology 2005 6:44

    Content type: Research article

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  37. Ras proteins are guanine-nucleotide-binding enzymes that couple cell surface receptors to intracellular signaling pathways controlling cell proliferation and differentiation, both in lower and higher eukaryote...

    Authors: Maddalena Arigoni, Enrico Bracco, Daniel F Lusche, Helmut Kae, Gerald Weeks and Salvatore Bozzaro

    Citation: BMC Cell Biology 2005 6:43

    Content type: Research article

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  38. Cultures of enterocytes and colonocytes represent valuable tools to study growth and differentiation of epithelial cells. In vitro models may be used to evaluate passage or toxicity of drugs, interactions of e...

    Authors: Dorina Rusu, Suzanne Loret, Olivier Peulen, Jacques Mainil and Guy Dandrifosse

    Citation: BMC Cell Biology 2005 6:42

    Content type: Research article

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  39. The plant peroxisomal multifunctional protein (MFP) possesses up to four enzymatic activities that are involved in catalyzing different reactions of fatty acid β-oxidation in the peroxisome matrix. In addition...

    Authors: Simon DX Chuong, Nam-Il Park, Michelle C Freeman, Robert T Mullen and Douglas G Muench

    Citation: BMC Cell Biology 2005 6:40

    Content type: Research article

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  40. Mammalian blood neutrophilic granulocytes are terminally differentiated cells, possessing extensive heterochromatin and lobulated (or ring-shaped) nuclei. Despite the extensive amount of heterochromatin, neutr...

    Authors: Donald E Olins and Ada L Olins

    Citation: BMC Cell Biology 2005 6:39

    Content type: Research article

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  41. The microenvironment surrounding cells can exert multiple effects on their biological responses. In particular the extracellular matrix surrounding cells can profoundly influence their behavior. It has been sh...

    Authors: Christina L Addison, Jacques E Nör, Huijun Zhao, Stephanie A Linn, Peter J Polverini and Christie E Delaney

    Citation: BMC Cell Biology 2005 6:38

    Content type: Research article

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  42. Normal cells possess a limited proliferative life span after which they enter a state of irreversible growth arrest. This process, known as replicative senescence, is accompanied by changes in gene expression ...

    Authors: Robert F Place, Emily J Noonan and Charles Giardina

    Citation: BMC Cell Biology 2005 6:37

    Content type: Research article

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  43. The actin cytoskeleton participates in many fundamental processes including the regulation of cell shape, motility, and adhesion. The remodeling of the actin cytoskeleton is dependent on actin binding proteins...

    Authors: Julaine Roffers-Agarwal, Jennifer B Xanthos and Jeffrey R Miller

    Citation: BMC Cell Biology 2005 6:36

    Content type: Research article

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  44. Members of the Kinesin-3 family of kinesin-like proteins mediate transport of axonal vesicles (KIF1A, KIF1Bβ), distribution of mitochondria (KIF1Bα) and anterograde Golgi to ER vesicle transport (KIF1C). Until...

    Authors: Marcin J Wozniak, Martina Melzer, Cornelia Dorner, Hans-Ulrich Haring and Reiner Lammers

    Citation: BMC Cell Biology 2005 6:35

    Content type: Research article

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  45. Hermansky-Pudlak syndrome (HPS) is a disorder of lysosome-related organelle biogenesis characterized by oculocutaneous albinism and prolonged bleeding. These clinical findings reflect defects in the formation ...

    Authors: Amanda Helip-Wooley, Wendy Westbroek, Heidi Dorward, Mieke Mommaas, Raymond E Boissy, William A Gahl and Marjan Huizing

    Citation: BMC Cell Biology 2005 6:33

    Content type: Research article

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2018 Journal Metrics

  • Citation Impact

    3.485 - 2-year Impact Factor
    3.227 - 5-year Impact Factor
    0.857 - Source Normalized Impact per Paper (SNIP)
    1.403 - SCImago Journal Rank (SJR)

    Usage 
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