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  1. Adhesion to extracellular matrix (ECM) components has been implicated in the proliferative and invasive properties of tumor cells. We investigated the ability of C6 glioma cells to attach to ECM components in vit...

    Authors: Claudia Beatriz Nedel Mendes de Aguiar, Bruno Lobão-Soares, Marcio Alvarez-Silva and Andréa Gonçalves Trentin

    Citation: BMC Cell Biology 2005 6:31

    Content type: Research article

    Published on:

  2. The amyloid precursor protein (APP) is transported via the secretory pathway to the cell surface, where it may be cleaved within its ectodomain by α-secretase, or internalized within clathrin-coated vesicles. ...

    Authors: Robyn M Carey, Brigitte A Balcz, Ignacio Lopez-Coviella and Barbara E Slack

    Citation: BMC Cell Biology 2005 6:30

    Content type: Research article

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  3. The Cajal body (CB) is a nuclear suborganelle involved in the biogenesis of small nuclear ribonucleoproteins (snRNPs), which are vital for pre-mRNA splicing. Newly imported Sm-class snRNPs traffic through CBs,...

    Authors: Hongzhi Xu, Z Brad Somers, Melvin L Robinson II and Michael D Hebert

    Citation: BMC Cell Biology 2005 6:29

    Content type: Research article

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  4. SMC proteins are key components of several protein complexes that perform vital tasks in different chromosome dynamics. Bacterial SMC forms a complex with ScpA and ScpB that is essential for chromosome arrange...

    Authors: Judita Mascarenhas, Arsen V Volkov, Cornelia Rinn, Jens Schiener, Reinhard Guckenberger and Peter L Graumann

    Citation: BMC Cell Biology 2005 6:28

    Content type: Research article

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  5. Hutchinson-Gilford progeria syndrome (HGPS, OMIM 176670) is a rare sporadic disorder with an incidence of approximately 1 per 8 million live births. The phenotypic appearance consists of short stature, sculptu...

    Authors: Mauro Paradisi, Dayle McClintock, Revekka L Boguslavsky, Christina Pedicelli, Howard J Worman and Karima Djabali

    Citation: BMC Cell Biology 2005 6:27

    Content type: Research article

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  6. During infection and inflammation, circulating blood monocytes migrate from the intravascular compartments to the extravascular compartments, where they mature into tissue macrophages. The maturation process p...

    Authors: Jun Zhou, Ping Zhu, Jian Li Jiang, Qing Zhang, Zhen Biao Wu, Xi Ying Yao, Hao Tang, Ning Lu, Yong Yang and Zhi Nan Chen

    Citation: BMC Cell Biology 2005 6:25

    Content type: Research article

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  7. Guanylic nucleotides are both macromolecules constituents and crucial regulators for a variety of cellular processes. Therefore, their intracellular concentration must be strictly controlled. Consistently both...

    Authors: Isabelle Sagot, Jacques Schaeffer and Bertrand Daignan-Fornier

    Citation: BMC Cell Biology 2005 6:24

    Content type: Research article

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  8. Two-photon-excitation fluorescence lifetime imaging (2P-FLIM) was used to investigate the association of protein kinase C alpha (PKCα) with caveolin in CHO cells. PKCα is found widely in the cytoplasm and nucl...

    Authors: Christopher D Stubbs, Stanley W Botchway, Simon J Slater and Anthony W Parker

    Citation: BMC Cell Biology 2005 6:22

    Content type: Research article

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  9. Recent studies indicate that the G protein-coupled receptor (GPCR) signaling machinery can serve as a direct target of reactive oxygen species, including nitric oxide (NO) and S-nitrosothiols (RSNOs). To gain ...

    Authors: Tarja Kokkola, Juha R Savinainen, Kati S Mönkkönen, Montse Durán Retamal and Jarmo T Laitinen

    Citation: BMC Cell Biology 2005 6:21

    Content type: Research article

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  10. Human cell types respond differently to infection by human immunodeficiency virus (HIV). Defining specific interactions between host cells and viral proteins is essential in understanding how viruses exploit c...

    Authors: Susanne Kramer-Hämmerle, Francesca Ceccherini-Silberstein, Christian Bickel, Horst Wolff, Michelle Vincendeau, Thomas Werner, Volker Erfle and Ruth Brack-Werner

    Citation: BMC Cell Biology 2005 6:20

    Content type: Research article

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  11. Time-lapse microscopic imaging provides a powerful approach for following changes in cell phenotype over time. Visible responses of whole cells can yield insight into functional changes that underlie physiolog...

    Authors: Alfred Bahnson, Charalambos Athanassiou, Douglas Koebler, Lei Qian, Tongying Shun, Donna Shields, Hui Yu, Hong Wang, Julie Goff, Tao Cheng, Raymond Houck and Lex Cowsert

    Citation: BMC Cell Biology 2005 6:19

    Content type: Methodology article

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  12. A number of transgenic mice carrying different deletions in the Locus Control Region (LCR) of the mouse tyrosinase (Tyr) gene have been developed and analysed in our laboratory. We require melanocytes from these ...

    Authors: Alfonso Lavado, Ander Matheu, Manuel Serrano and Lluís Montoliu

    Citation: BMC Cell Biology 2005 6:18

    Content type: Methodology article

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  13. EB1 is a microtubule tip-associated protein that interacts with the APC tumour suppressor protein and the p150glued subunit of dynactin. We previously reported that an EB1 deletion mutant that retains both of ...

    Authors: Nick P Riess, Kelly Milward, Tracy Lee, Matthew Adams, Jon M Askham and Ewan E Morrison

    Citation: BMC Cell Biology 2005 6:17

    Content type: Research article

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  14. Splicing variants of human cathepsinB primary transcripts (CB(-2,3)) result in an expression product product which lacks the signal peptide and parts of the propeptide. This naturally truncated Δ51CB is thus unab...

    Authors: Felix Bestvater, Claudia Dallner and Eberhard Spiess

    Citation: BMC Cell Biology 2005 6:16

    Content type: Research article

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  15. The small GTPase rab1a and its isoform rab1b are essential regulating components in the vesicle transport between the ER and the Golgi apparatus. Rab1 is thought to act as a molecular switch and can change bet...

    Authors: Michael Bayer, Julia Fischer, Joachim Kremerskothen, Edith Ossendorf, Theodoros Matanis, Magdalena Konczal, Thomas Weide and Angelika Barnekow

    Citation: BMC Cell Biology 2005 6:15

    Content type: Research article

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  16. Stimulation of Dictyostelium discoideum with cAMP evokes an elevation of the cytosolic free Ca2+ concentration ([Ca2+]i). The [Ca2+]i-change is composed of liberation of stored Ca2+ and extracellular Ca2+-entry. ...

    Authors: Ralph H Schaloske, Daniel F Lusche, Karen Bezares-Roder, Kathrin Happle, Dieter Malchow and Christina Schlatterer

    Citation: BMC Cell Biology 2005 6:13

    Content type: Research article

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  17. Differentiating Dictyostelium discoideum amoebae respond upon cAMP-stimulation with an increase in the cytosolic free Ca2+ concentration ([Ca2+]i) that is composed of liberation of stored Ca2+ and extracellular C...

    Authors: Daniel F Lusche, Karen Bezares-Roder, Kathrin Happle and Christina Schlatterer

    Citation: BMC Cell Biology 2005 6:12

    Content type: Research article

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  18. The Scar/WAVE family of proteins mediates signals to actin assembly by direct activation of the Arp2/3 complex. These proteins have been characterised as major regulators of lamellipodia formation downstream o...

    Authors: Craig F Stovold, Thomas H Millard and Laura M Machesky

    Citation: BMC Cell Biology 2005 6:11

    Content type: Research article

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  19. Bacterial actin-like proteins have been shown to perform essential functions in several aspects of cellular physiology. They affect cell growth, cell shape, chromosome segregation and polar localization of pro...

    Authors: Hervé Joël Defeu Soufo and Peter L Graumann

    Citation: BMC Cell Biology 2005 6:10

    Content type: Research article

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  20. The growth of new blood vessels in adult life requires the initiation of endothelial cell migration and proliferation from pre-existing vessels in addition to the recruitment and differentiation of circulating...

    Authors: Salman Rahman, Yatin Patel, Jacqueline Murray, Kirti V Patel, Rushika Sumathipala, Michael Sobel and Errol S Wijelath

    Citation: BMC Cell Biology 2005 6:8

    Content type: Research article

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  21. Gliomas are "intraparenchymally metastatic" tumors, invading the brain in a non-destructive way that suggests cooperation between glioma cells and their environment. Recent studies using an engineered rodent C...

    Authors: Roxane Oliveira, Christo Christov, Jean Sébastien Guillamo, Sophie de Boüard, Stéphane Palfi, Laurent Venance, Marcienne Tardy and Marc Peschanski

    Citation: BMC Cell Biology 2005 6:7

    Content type: Research article

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  22. Human α-galactosidase A (α-GAL) and α-N-acetylgalactosaminidase (α-NAGA) are presumed to share a common ancestor. Deficiencies of these enzymes cause two well-characterized human lysosomal storage disorders (L...

    Authors: Jana Hujová, Jakub Sikora, Robert Dobrovolný, Helena Poupětová, Jana Ledvinová, Marta Kostrouchová and Martin Hřebíček

    Citation: BMC Cell Biology 2005 6:5

    Content type: Research article

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  23. IEC-18 cells are a non-transformed, immortal cell line derived from juvenile rat ileal crypt cells. They may have experimental advantages over tumor-derived gastrointestinal lineages, including preservation of...

    Authors: Phillip V Gordon, Jessica B Paxton and Nena S Fox

    Citation: BMC Cell Biology 2005 6:2

    Content type: Methodology article

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  24. At sites of cell adhesion, proteins exist that not only perform structural tasks but also have a signaling function. Previously, we found that the Lipoma Preferred Partner (LPP) protein is localized at sites o...

    Authors: Marleen MR Petit, Sandra MP Meulemans, Philippe Alen, Torik AY Ayoubi, Erik Jansen and Wim JM Van de Ven

    Citation: BMC Cell Biology 2005 6:1

    Content type: Research article

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  25. The formylpeptide receptor family members FPR and FPRL1, expressed in myeloid phagocytes, belong to the G-protein coupled seven transmembrane receptor family (GPCRs). They share a high degree of sequence simil...

    Authors: Huamei Fu, Lena Björkman, Paul Janmey, Anna Karlsson, Jennie Karlsson, Charlotta Movitz and Claes Dahlgren

    Citation: BMC Cell Biology 2004 5:50

    Content type: Research article

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  26. A number of proteins accumulate in the spindle midzone and midbody of dividing animal cells. Besides proteins essential for cytokinesis, there are also components essential for interphase functions, suggesting...

    Authors: Maki Murata-Hori, Greenfield Sluder and Yu-li Wang

    Citation: BMC Cell Biology 2004 5:49

    Content type: Research article

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  27. Through in vivo loss-of-function studies, vertebrate members of the Male abnormal 21 (mab-21) gene family have been implicated in gastrulation, neural tube formation and eye morphogenesis. Despite mounting eviden...

    Authors: Danila Baldessari, Aurora Badaloni, Renato Longhi, Vincenzo Zappavigna and G Giacomo Consalez

    Citation: BMC Cell Biology 2004 5:48

    Content type: Research article

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  28. Fibroblasts, as connective tissue cells, are able to transform into another cell type including smooth muscle cells. α1A-adrenergic receptor (α1A-AR) stimulation in rat-1 fibroblasts is coupled to cAMP production...

    Authors: Abdelwahab E Saeed, Jean-Hugues Parmentier and Kafait U Malik

    Citation: BMC Cell Biology 2004 5:47

    Content type: Research article

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  29. Recent interest in the function of the nuclear lamina has been provoked by the discovery of lamin A/C mutations in the laminopathy diseases. However, it is not understood why mutations in lamin A give such a r...

    Authors: Susan Gilchrist, Nick Gilbert, Paul Perry, Cecilia Östlund, Howard J Worman and Wendy A Bickmore

    Citation: BMC Cell Biology 2004 5:46

    Content type: Research article

    Published on:

  30. The dynamics of nuclear organization, nuclear bodies and RNPs in particular has been the focus of many studies. To understand their function, knowledge of their spatial nuclear position and temporal translocat...

    Authors: Christian P Bacher, Michaela Reichenzeller, Chaitanya Athale, Harald Herrmann and Roland Eils

    Citation: BMC Cell Biology 2004 5:45

    Content type: Research article

    Published on:

  31. Between cell divisions the chromatin fiber of each chromosome is restricted to a subvolume of the interphase cell nucleus called chromosome territory. The internal organization of these chromosome territories ...

    Authors: Sonja Stadler, Verena Schnapp, Robert Mayer, Stefan Stein, Christoph Cremer, Constanze Bonifer, Thomas Cremer and Steffen Dietzel

    Citation: BMC Cell Biology 2004 5:44

    Content type: Research article

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  32. The Coxsackie and adenovirus receptor (CAR) has a restricted expression pattern in the adult. In skeletal muscle, although CAR is expressed in immature fibers, its transcript levels are barely detectable in ma...

    Authors: Christian A Shaw, Paul C Holland, Michael Sinnreich, Carol Allen, Kerstin Sollerbrant, George Karpati and Josephine Nalbantoglu

    Citation: BMC Cell Biology 2004 5:42

    Content type: Research article

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  33. Viruses are obligate intracellular parasites that rely upon the host cell for different steps in their life cycles. The characterization of cellular genes required for virus infection and/or cell killing will ...

    Authors: Edward L Organ, Jinsong Sheng, H Earl Ruley and Donald H Rubin

    Citation: BMC Cell Biology 2004 5:41

    Content type: Research article

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  34. Checkpoint mechanisms prevent cell cycle transitions until previous events have been completed or damaged DNA has been repaired. In fission yeast, checkpoint mechanisms are known to regulate entry into mitosis...

    Authors: Esben A Nilssen, Marianne Synnes, Tonje Tvegård, Heidi Vebø, Erik Boye and Beáta Grallert

    Citation: BMC Cell Biology 2004 5:40

    Content type: Research article

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  35. Erythroid nuclear cells (ENC) of the bone marrow (BM) have not previously been considered as important producers of wide spectrum of haemo- and immunoregulatory cytokines. The aim of the current work was to co...

    Authors: Sergey V Sennikov, Tatyana V Injelevskaya, Sergey V Krysov, Alexandr N Silkov, Igor B Kovinev, Natalya J Dyachkova, Anton N Zenkov, Mary I Loseva and Vladimir A Kozlov

    Citation: BMC Cell Biology 2004 5:39

    Content type: Research article

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  36. The Janus kinase (JAK) cascade is an essential and well-conserved pathway required to transduce signals for a variety of ligands in both vertebrates and invertebrates. While activation of the pathway is essent...

    Authors: Jason S Rawlings, Gabriela Rennebeck, Susan MW Harrison, Rongwen Xi and Douglas A Harrison

    Citation: BMC Cell Biology 2004 5:38

    Content type: Research article

    Published on:

  37. Conlon and Raff propose that mammalian cells grow linearly during the division cycle. According to Conlon and Raff, cells growing linearly do not need a size checkpoint to maintain a constant distribution of c...

    Authors: Stephen Cooper

    Citation: BMC Cell Biology 2004 5:35

    Content type: Debate

    Published on:

  38. Research on olfactory G-protein coupled receptors (GPCRs) has been severely impeded by poor functional expression in heterologous systems. Previously, we demonstrated that inefficient olfactory receptor (OR) e...

    Authors: Min Lu, Lena Staszewski, Fernando Echeverri, Hong Xu and Bryan D Moyer

    Citation: BMC Cell Biology 2004 5:34

    Content type: Research article

    Published on:

2018 Journal Metrics

  • Citation Impact

    3.485 - 2-year Impact Factor
    3.227 - 5-year Impact Factor
    0.857 - Source Normalized Impact per Paper (SNIP)
    1.403 - SCImago Journal Rank (SJR)

    Usage 
    681,235 downloads


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