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  1. To explore the relationship between spatial genome organization and gene expression in the interphase nucleus, we used a genomic imprinting model, which offers parental-specific gene expression. Using 3D FISH ...

    Authors: Yvette Lahbib-Mansais, Harmonie Barasc, Maria Marti-Marimon, Florence Mompart, Eddie Iannuccelli, David Robelin, Juliette Riquet and Martine Yerle-Bouissou

    Citation: BMC Cell Biology 2016 17:35

    Content type: Research article

    Published on:

  2. Mitochondrial dysfunction is one of the leading causes of neurological disorders in humans. Mitochondrial perturbations lead to adaptive mechanisms that include HIF-1 stabilization, though the consequences of ...

    Authors: Muntasir Kamal, Dayana R. D’Amora and Terrance J. Kubiseski

    Citation: BMC Cell Biology 2016 17:34

    Content type: Research article

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  3. Genomes of eukaryotes exist as chromatin, and it is known that different chromatin states can influence gene regulation. Chromatin is not a static structure, but is known to be dynamic and vary between cells. ...

    Authors: David Dickerson, Marek Gierliński, Vijender Singh, Etsushi Kitamura, Graeme Ball, Tomoyuki U. Tanaka and Tom Owen-Hughes

    Citation: BMC Cell Biology 2016 17:33

    Content type: Research

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  4. Formins are a highly conserved family of cytoskeletal remodeling proteins. A growing body of evidence suggests that formins play key roles in the progression and spread of a variety of cancers. There are 15 hu...

    Authors: Christine Péladeau, Allan Heibein, Melissa T. Maltez, Sarah J. Copeland and John W. Copeland

    Citation: BMC Cell Biology 2016 17:32

    Content type: Research article

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  5. The serine/threonine kinase PAK1 is an important regulator of cell motility. Both PAK1 and the hormone/cytokine prolactin (PRL) have been implicated in breast cancer cell motility, however, the exact mechanism...

    Authors: Alan Hammer and Maria Diakonova

    Citation: BMC Cell Biology 2016 17:31

    Content type: Research article

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  6. Karyotypic integrity is essential for the successful germline transmission of alleles mutated in embryonic stem (ES) cells. Classical methods for the identification of aneuploidy involve cytological analyses t...

    Authors: Gemma F. Codner, Loic Lindner, Adam Caulder, Marie Wattenhofer-Donzé, Adam Radage, Annelyse Mertz, Benjamin Eisenmann, Joffrey Mianné, Edward P. Evans, Colin V. Beechey, Martin D. Fray, Marie-Christine Birling, Yann Hérault, Guillaume Pavlovic and Lydia Teboul

    Citation: BMC Cell Biology 2016 17:30

    Content type: Methodology article

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  7. Antigenic stimulation of the T cell receptor (TCR) initiates a change from a resting state into an activated one, which ultimately results in proliferation and the acquisition of effector functions. To accompl...

    Authors: Clemens Cammann, Alexander Rath, Udo Reichl, Holger Lingel, Monika Brunner-Weinzierl, Luca Simeoni, Burkhart Schraven and Jonathan A. Lindquist

    Citation: BMC Cell Biology 2016 17:28

    Content type: Research article

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  8. Vacuolar-type proton pumps help maintain acid–base homeostasis either within intracellular compartments or at specialised plasma membranes. In mammals they are made up of 13 subunits, which form two functional...

    Authors: Zoe J. Golder and Fiona E. Karet Frankl

    Citation: BMC Cell Biology 2016 17:27

    Content type: Research article

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  9. Nesprin-1-giant (1008kD) is a protein of the outer nuclear membrane that links nuclei to the actin cytoskeleton via amino-terminal calponin homology domains. The short nesprin-1 isoform, nesprin-1-α2, is prese...

    Authors: Ian Holt, Nguyen Thuy Duong, Qiuping Zhang, Le Thanh Lam, Caroline A. Sewry, Kamel Mamchaoui, Catherine M. Shanahan and Glenn E. Morris

    Citation: BMC Cell Biology 2016 17:26

    Content type: Research article

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  10. Vascular endothelial dysfunction is the closely related determinant of ischemic heart disease (IHD). Endothelial dysfunction and ischemia/reperfusion injury (IRI) have been associated with an increase in micro...

    Authors: Qi Zhang, Man Shang, Mengxiao Zhang, Yao Wang, Yan Chen, Yanna Wu, Minglin Liu, Junqiu Song and Yanxia Liu

    Citation: BMC Cell Biology 2016 17:25

    Content type: Research article

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  11. Flagella and cilia are fine thread-like organelles protruding from cells that harbour them. The typical ‘9 + 2’ cilia confer motility on these cells. Although the mechanistic details of motility remain elusive...

    Authors: Venkatramanan G. Rao, Ruhi B. Sarafdar, Twinkle S. Chowdhury, Priyanka Sivadas, Pinfen Yang, Prabhakar M. Dongre and Jacinta S. D’Souza

    Citation: BMC Cell Biology 2016 17:24

    Content type: Research article

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  12. Ankyrin repeats and LEM domain containing protein 1 (Ankle1) belongs to the LEM protein family, whose members share a chromatin-interacting LEM motif. Unlike most other LEM proteins, Ankle1 is not an integral ...

    Authors: Livija Zlopasa, Andreas Brachner and Roland Foisner

    Citation: BMC Cell Biology 2016 17:23

    Content type: Research article

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  13. Internalization of gap junction plaques results in the formation of annular gap junction vesicles. The factors that regulate the coordinated internalization of the gap junction plaques to form annular gap junc...

    Authors: Matthias M. Falk, Cheryl L. Bell, Rachael M. Kells Andrews and Sandra A. Murray

    Citation: BMC Cell Biology 2016 17(Suppl 1):S22

    Content type: Review

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    This article is part of a Supplement: Volume 17 Supplement 1

  14. Connexins mediate intercellular communication by assembling into hexameric channel complexes that act as hemichannels and gap junction channels. Most connexins are characterized by a very rapid turn-over in a ...

    Authors: Jegan Iyyathurai, Jean-Paul Decuypere, Luc Leybaert, Catheleyne D’hondt and Geert Bultynck

    Citation: BMC Cell Biology 2016 17(Suppl 1):S20

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  15. Electron micrographs revealed the presence of gap junctions in osteoblastic cells over 40 years ago. These intercellular channels formed from connexins are present in bone forming osteoblasts, bone resorbing o...

    Authors: Lilian I. Plotkin, Dale W. Laird and Joelle Amedee

    Citation: BMC Cell Biology 2016 17(Suppl 1):S19

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  16. Mutations in human connexin (Cx) genes have been related to diseases, which we termed connexinopathies. Such hereditary disorders include nonsyndromic or syndromic deafness (Cx26, Cx30), Charcot Marie Tooth di...

    Authors: Isaac E. García, Pavel Prado, Amaury Pupo, Oscar Jara, Diana Rojas-Gómez, Paula Mujica, Carolina Flores-Muñoz, Jorge González-Casanova, Carolina Soto-Riveros, Bernardo I. Pinto, Mauricio A. Retamal, Carlos González and Agustín D. Martínez

    Citation: BMC Cell Biology 2016 17(Suppl 1):S17

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  17. Mutations in the gene encoding for dysferlin cause recessive autosomal muscular dystrophies called dysferlinopathies. These mutations induce several alterations in skeletal muscles, including, inflammation, in...

    Authors: Luis A. Cea, Jorge A. Bevilacqua, Christian Arriagada, Ana María Cárdenas, Anne Bigot, Vincent Mouly, Juan C. Sáez and Pablo Caviedes

    Citation: BMC Cell Biology 2016 17(Suppl 1):15

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  18. Gap junctions mediate electrical synaptic transmission between neurons. While the actions of neurotransmitter modulators on the conductance of gap junctions have been extensively documented, increasing evidenc...

    Authors: Julie S. Haas, Corey M. Greenwald and Alberto E. Pereda

    Citation: BMC Cell Biology 2016 17(Suppl 1):14

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  19. Electrical synapses are an omnipresent feature of nervous systems, from the simple nerve nets of cnidarians to complex brains of mammals. Formed by gap junction channels between neurons, electrical synapses al...

    Authors: Sebastian Curti and John O’Brien

    Citation: BMC Cell Biology 2016 17(Suppl 1):13

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  20. Communication among cells via direct cell-cell contact by connexin gap junctions, or between cell and extracellular environment via pannexin channels or connexin hemichannels, is a key factor in cell function ...

    Authors: Jean X. Jiang and Silvia Penuela

    Citation: BMC Cell Biology 2016 17(Suppl 1):S12

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  21. Post-translational modifications of connexins play an important role in the regulation of gap junction and hemichannel permeability. The prerequisite for the formation of functional gap junction channels is th...

    Authors: Kristin Pogoda, Petra Kameritsch, Mauricio A. Retamal and José L. Vega

    Citation: BMC Cell Biology 2016 17(Suppl 1):11

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  22. Connexins and pannexins share very similar structures and functions; they also exhibit overlapping expression in many stages of neuronal development. Here, we review evidence implicating connexin- and pannexin...

    Authors: Leigh Anne Swayne and Steffany A. L. Bennett

    Citation: BMC Cell Biology 2016 17(Suppl 1):S10

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  23. Endothelial-mesenchymal transition (EndoMT) is a major source of myofibroblast formation in kidney fibrosis. Our previous study showed a profibrotic role for matrix metalloproteinase 9 (MMP-9) in kidney fibros...

    Authors: Ye Zhao, Xi Qiao, Lihua Wang, Tian Kui Tan, Hong Zhao, Yun Zhang, Jianlin Zhang, Padmashree Rao, Qi Cao, Yiping Wang, Ya Wang, Yuan Min Wang, Vincent W. S. Lee, Stephen I. Alexander, David C. H. Harris and Guoping Zheng

    Citation: BMC Cell Biology 2016 17:21

    Content type: Research article

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  24. IL-27 is a multifunctional cytokine that has both pro-inflammatory and anti-inflammatory functions. Although IL-27 has been shown to potently inhibit lung fibrosis, the detailed mechanism of IL-27 in this proc...

    Authors: Zhaoxing Dong, Wenlin Tai, Wen Lei, Yin Wang, ZhenKun Li and Tao Zhang

    Citation: BMC Cell Biology 2016 17:7

    Content type: Research article

    Published on:

  25. The editors of BMC Cell Biology would like to thank all those who have contributed reviews to the journal in Volume 16 (2015).

    Authors: Timothy R. Sands

    Citation: BMC Cell Biology 2016 17:6

    Content type: Reviewer acknowledgement

    Published on:

  26. Gap junctions facilitate exchange of small molecules between adjacent cells, serving a crucial function for the maintenance of cellular homeostasis. Mutations in connexins, the basic unit of gap junctions, are...

    Authors: Hande Aypek, Veysel Bay and Gülistan Meşe

    Citation: BMC Cell Biology 2016 17:5

    Content type: Research article

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  27. The intestinal cells of Caenorhabditis elegans are filled with heterogeneous granular organelles that are associated with specific organ functions. The best studied of these organelles are lipid droplets and acid...

    Authors: Takahiro Tanji, Kenji Nishikori, Syoko Haga, Yuki Kanno, Yusuke Kobayashi, Mai Takaya, Keiko Gengyo-Ando, Shohei Mitani, Hirohisa Shiraishi and Ayako Ohashi-Kobayashi

    Citation: BMC Cell Biology 2016 17:4

    Content type: Research article

    Published on:

  28. Membranous tunneling tubes (TTs) are a recently discovered new form of communication between remote cells allowing their electrical synchronization, migration, and transfer of cellular materials. TTs have been...

    Authors: Lina Rimkutė, Vaidas Jotautis, Alina Marandykina, Renata Sveikatienė, Ieva Antanavičiūtė and Vytenis Arvydas Skeberdis

    Citation: BMC Cell Biology 2016 17:3

    Content type: Research article

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  29. The small G-protein Rap1 is an important regulator of cellular adhesion in Dictyostelium, however so far the downstream signalling pathways for cell adhesion are not completely characterized. In mammalian cells t...

    Authors: Katarzyna Plak, Henderikus Pots, Peter J. M. Van Haastert and Arjan Kortholt

    Citation: BMC Cell Biology 2016 17:1

    Content type: Research article

    Published on:

  30. Seipin is required for the correct assembly of cytoplasmic lipid droplets. In the absence of the yeast seipin homolog Sei1p (formerly Fld1p), droplets are slow to bud from the endoplasmic reticulum, lack the n...

    Authors: Sungwon Han, Derk D. Binns, Yu-Fang Chang and Joel M. Goodman

    Citation: BMC Cell Biology 2015 16:29

    Content type: Research article

    Published on:

  31. The nucleolus is a multi-domain enriched with proteins involved in ribosome biogenesis, cell cycle and apoptosis control, viral replication and differentiation of stem cells. Several authors have suggested a r...

    Authors: Donatella Ponti, Daniela Bastianelli, Paolo Rosa, Luca Pacini, Mohsen Ibrahim, Erino Angelo Rendina, Giuseppe Ragona and Antonella Calogero

    Citation: BMC Cell Biology 2015 16:27

    Content type: Research article

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  32. The membrane anchored kinase, LMTK2, is a serine/threonine kinase predominantly localized to endosomal compartments. LMTK2 has been shown to be involved in the trafficking of the CFTR ion channel, the androgen...

    Authors: E. C. Butler and Neil A. Bradbury

    Citation: BMC Cell Biology 2015 16:26

    Content type: Research article

    Published on:

  33. To analyze the ways and methods of signaling pathways in regulating cell cycle progression of NIH3T3 at transcriptional level, we modeled cell cycle of NIH3T3 and found that G1 phase of NIH3T3 cell cycle was a...

    Authors: Cuifang Chang, Zhipeng Niu, Ningning Gu, Weiming Zhao, Gaiping Wang, Yifeng Jia, Deming Li and Cunshuan Xu

    Citation: BMC Cell Biology 2015 16:25

    Content type: Research article

    Published on:

  34. Endocytosis of activated EGF receptor (EGFR) to specific endocytic compartments is required to terminate EGF signaling. Trafficking of EGFR relies on microtubule tracks that transport the cargo vesicle to thei...

    Authors: Seung Joon Lee, Zhiqin Li, Alisa Litan, Soonmoon Yoo and Sigrid A. Langhans

    Citation: BMC Cell Biology 2015 16:24

    Content type: Research article

    Published on:

  35. The traditional problems of performing skeletal muscle cell cultures derived from mammalian or avian species are limited myotube differentiation, and transient myotube persistence which greatly restricts the a...

    Authors: Sujith Sebastian, Leah Goulding, Suresh V. Kuchipudi and Kin-Chow Chang

    Citation: BMC Cell Biology 2015 16:23

    Content type: Methodology article

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  36. Environmental factors are important for stem cell lineage specification, and increasing evidence indicates that the nanoscale geometry/topography of the extracellular matrix (ECM) directs stem cell fate. Recen...

    Authors: Yan Chen, Di Zeng, Lu Ding, Xiao-Li Li, Xiong-Tao Liu, Wen-Ju Li, Ting Wei, Song Yan, Jiang-Hui Xie, Li Wei and Qiang-Sun Zheng

    Citation: BMC Cell Biology 2015 16:22

    Content type: Research article

    Published on:

  37. Preeclampsia, one of the major disorders of pregnancy, is characterized by inadequate trophoblast invasion and defective trophoblast-mediated remodeling of placental vasculature. MicroRNA-34a (miR-34a) has bee...

    Authors: Manni Sun, Haiying Chen, Jing Liu, Chunxiao Tong and Tao Meng

    Citation: BMC Cell Biology 2015 16:21

    Content type: Research article

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  38. Recent studies have reported the roles of Hyaluronic acid (HA) chains of diverse length in wound repair, especially considering the simultaneous occurrence in vivo of both high- (H-HA) and low-molecular weight (L...

    Authors: Antonella D’Agostino, Antonietta Stellavato, Teresa Busico, Agata Papa, Virginia Tirino, Gianpaolo Papaccio, Annalisa La Gatta, Mario De Rosa and Chiara Schiraldi

    Citation: BMC Cell Biology 2015 16:19

    Content type: Research article

    Published on:

  39. Cells contain several inositol pyrophosphates (PP-InsPs; also known as diphosphoinositol polyphosphates), which play pivotal roles in cellular and organismic homeostasis. It has been proposed that determining ...

    Authors: Sheila T. Yong, Hoai-Nghia Nguyen, Jae H. Choi, Carl D. Bortner, Jason Williams, Niyas K. Pulloor, Manoj N. Krishnan and Stephen B. Shears

    Citation: BMC Cell Biology 2015 16:17

    Content type: Research article

    Published on:

2018 Journal Metrics

  • Citation Impact

    3.485 - 2-year Impact Factor
    3.227 - 5-year Impact Factor
    0.857 - Source Normalized Impact per Paper (SNIP)
    1.403 - SCImago Journal Rank (SJR)

    Usage 
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