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  1. Gap junctions mediate electrical synaptic transmission between neurons. While the actions of neurotransmitter modulators on the conductance of gap junctions have been extensively documented, increasing evidenc...

    Authors: Julie S. Haas, Corey M. Greenwald and Alberto E. Pereda

    Citation: BMC Cell Biology 2016 17(Suppl 1):14

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  2. Electrical synapses are an omnipresent feature of nervous systems, from the simple nerve nets of cnidarians to complex brains of mammals. Formed by gap junction channels between neurons, electrical synapses al...

    Authors: Sebastian Curti and John O’Brien

    Citation: BMC Cell Biology 2016 17(Suppl 1):13

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  3. Post-translational modifications of connexins play an important role in the regulation of gap junction and hemichannel permeability. The prerequisite for the formation of functional gap junction channels is th...

    Authors: Kristin Pogoda, Petra Kameritsch, Mauricio A. Retamal and José L. Vega

    Citation: BMC Cell Biology 2016 17(Suppl 1):11

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  4. Endothelial-mesenchymal transition (EndoMT) is a major source of myofibroblast formation in kidney fibrosis. Our previous study showed a profibrotic role for matrix metalloproteinase 9 (MMP-9) in kidney fibros...

    Authors: Ye Zhao, Xi Qiao, Lihua Wang, Tian Kui Tan, Hong Zhao, Yun Zhang, Jianlin Zhang, Padmashree Rao, Qi Cao, Yiping Wang, Ya Wang, Yuan Min Wang, Vincent W. S. Lee, Stephen I. Alexander, David C. H. Harris and Guoping Zheng

    Citation: BMC Cell Biology 2016 17:21

    Content type: Research article

    Published on:

  5. IL-27 is a multifunctional cytokine that has both pro-inflammatory and anti-inflammatory functions. Although IL-27 has been shown to potently inhibit lung fibrosis, the detailed mechanism of IL-27 in this proc...

    Authors: Zhaoxing Dong, Wenlin Tai, Wen Lei, Yin Wang, ZhenKun Li and Tao Zhang

    Citation: BMC Cell Biology 2016 17:7

    Content type: Research article

    Published on:

  6. The editors of BMC Cell Biology would like to thank all those who have contributed reviews to the journal in Volume 16 (2015).

    Authors: Timothy R. Sands

    Citation: BMC Cell Biology 2016 17:6

    Content type: Reviewer acknowledgement

    Published on:

  7. Gap junctions facilitate exchange of small molecules between adjacent cells, serving a crucial function for the maintenance of cellular homeostasis. Mutations in connexins, the basic unit of gap junctions, are...

    Authors: Hande Aypek, Veysel Bay and Gülistan Meşe

    Citation: BMC Cell Biology 2016 17:5

    Content type: Research article

    Published on:

  8. The intestinal cells of Caenorhabditis elegans are filled with heterogeneous granular organelles that are associated with specific organ functions. The best studied of these organelles are lipid droplets and acid...

    Authors: Takahiro Tanji, Kenji Nishikori, Syoko Haga, Yuki Kanno, Yusuke Kobayashi, Mai Takaya, Keiko Gengyo-Ando, Shohei Mitani, Hirohisa Shiraishi and Ayako Ohashi-Kobayashi

    Citation: BMC Cell Biology 2016 17:4

    Content type: Research article

    Published on:

  9. Membranous tunneling tubes (TTs) are a recently discovered new form of communication between remote cells allowing their electrical synchronization, migration, and transfer of cellular materials. TTs have been...

    Authors: Lina Rimkutė, Vaidas Jotautis, Alina Marandykina, Renata Sveikatienė, Ieva Antanavičiūtė and Vytenis Arvydas Skeberdis

    Citation: BMC Cell Biology 2016 17:3

    Content type: Research article

    Published on:

  10. The small G-protein Rap1 is an important regulator of cellular adhesion in Dictyostelium, however so far the downstream signalling pathways for cell adhesion are not completely characterized. In mammalian cells t...

    Authors: Katarzyna Plak, Henderikus Pots, Peter J. M. Van Haastert and Arjan Kortholt

    Citation: BMC Cell Biology 2016 17:1

    Content type: Research article

    Published on:

  11. Seipin is required for the correct assembly of cytoplasmic lipid droplets. In the absence of the yeast seipin homolog Sei1p (formerly Fld1p), droplets are slow to bud from the endoplasmic reticulum, lack the n...

    Authors: Sungwon Han, Derk D. Binns, Yu-Fang Chang and Joel M. Goodman

    Citation: BMC Cell Biology 2015 16:29

    Content type: Research article

    Published on:

  12. The nucleolus is a multi-domain enriched with proteins involved in ribosome biogenesis, cell cycle and apoptosis control, viral replication and differentiation of stem cells. Several authors have suggested a r...

    Authors: Donatella Ponti, Daniela Bastianelli, Paolo Rosa, Luca Pacini, Mohsen Ibrahim, Erino Angelo Rendina, Giuseppe Ragona and Antonella Calogero

    Citation: BMC Cell Biology 2015 16:27

    Content type: Research article

    Published on:

  13. The membrane anchored kinase, LMTK2, is a serine/threonine kinase predominantly localized to endosomal compartments. LMTK2 has been shown to be involved in the trafficking of the CFTR ion channel, the androgen...

    Authors: E. C. Butler and Neil A. Bradbury

    Citation: BMC Cell Biology 2015 16:26

    Content type: Research article

    Published on:

  14. To analyze the ways and methods of signaling pathways in regulating cell cycle progression of NIH3T3 at transcriptional level, we modeled cell cycle of NIH3T3 and found that G1 phase of NIH3T3 cell cycle was a...

    Authors: Cuifang Chang, Zhipeng Niu, Ningning Gu, Weiming Zhao, Gaiping Wang, Yifeng Jia, Deming Li and Cunshuan Xu

    Citation: BMC Cell Biology 2015 16:25

    Content type: Research article

    Published on:

  15. Endocytosis of activated EGF receptor (EGFR) to specific endocytic compartments is required to terminate EGF signaling. Trafficking of EGFR relies on microtubule tracks that transport the cargo vesicle to thei...

    Authors: Seung Joon Lee, Zhiqin Li, Alisa Litan, Soonmoon Yoo and Sigrid A. Langhans

    Citation: BMC Cell Biology 2015 16:24

    Content type: Research article

    Published on:

  16. The traditional problems of performing skeletal muscle cell cultures derived from mammalian or avian species are limited myotube differentiation, and transient myotube persistence which greatly restricts the a...

    Authors: Sujith Sebastian, Leah Goulding, Suresh V. Kuchipudi and Kin-Chow Chang

    Citation: BMC Cell Biology 2015 16:23

    Content type: Methodology article

    Published on:

  17. Environmental factors are important for stem cell lineage specification, and increasing evidence indicates that the nanoscale geometry/topography of the extracellular matrix (ECM) directs stem cell fate. Recen...

    Authors: Yan Chen, Di Zeng, Lu Ding, Xiao-Li Li, Xiong-Tao Liu, Wen-Ju Li, Ting Wei, Song Yan, Jiang-Hui Xie, Li Wei and Qiang-Sun Zheng

    Citation: BMC Cell Biology 2015 16:22

    Content type: Research article

    Published on:

  18. Preeclampsia, one of the major disorders of pregnancy, is characterized by inadequate trophoblast invasion and defective trophoblast-mediated remodeling of placental vasculature. MicroRNA-34a (miR-34a) has bee...

    Authors: Manni Sun, Haiying Chen, Jing Liu, Chunxiao Tong and Tao Meng

    Citation: BMC Cell Biology 2015 16:21

    Content type: Research article

    Published on:

  19. Recent studies have reported the roles of Hyaluronic acid (HA) chains of diverse length in wound repair, especially considering the simultaneous occurrence in vivo of both high- (H-HA) and low-molecular weight (L...

    Authors: Antonella D’Agostino, Antonietta Stellavato, Teresa Busico, Agata Papa, Virginia Tirino, Gianpaolo Papaccio, Annalisa La Gatta, Mario De Rosa and Chiara Schiraldi

    Citation: BMC Cell Biology 2015 16:19

    Content type: Research article

    Published on:

  20. Cells contain several inositol pyrophosphates (PP-InsPs; also known as diphosphoinositol polyphosphates), which play pivotal roles in cellular and organismic homeostasis. It has been proposed that determining ...

    Authors: Sheila T. Yong, Hoai-Nghia Nguyen, Jae H. Choi, Carl D. Bortner, Jason Williams, Niyas K. Pulloor, Manoj N. Krishnan and Stephen B. Shears

    Citation: BMC Cell Biology 2015 16:17

    Content type: Research article

    Published on:

  21. Previously published reports indicated that some enzymes of the central carbon metabolism (CCM), particularly those involved in glycolysis and the tricarboxylic acid cycle, may contribute to regulation of DNA ...

    Authors: Aleksandra Konieczna, Aneta Szczepańska, Karolina Sawiuk, Grzegorz Węgrzyn and Robert Łyżeń

    Citation: BMC Cell Biology 2015 16:16

    Content type: Research article

    Published on:

  22. Polycystin-1 (PC-1) is a large plasma membrane receptor, encoded by the PKD1 gene, which is mutated in most cases of Autosomal Dominant Polycystic Kidney Disease (ADPKD). The disease is characterized by renal cys...

    Authors: Maddalena Castelli, Chiara De Pascalis, Gianfranco Distefano, Nadia Ducano, Amanda Oldani, Letizia Lanzetti and Alessandra Boletta

    Citation: BMC Cell Biology 2015 16:15

    Content type: Research article

    Published on:

  23. Optineurin is a gene associated with normal tension glaucoma and amyotrophic lateral sclerosis. It has been reported previously that in cultured RGC5 cells, the turnover of endogenous optineurin involves mainl...

    Authors: Hongyu Ying, Sanja Turturro, Tara Nguyen, Xiang Shen, Ruth Zelkha, Elaine C Johnson, John C Morrison and Beatrice YJT Yue

    Citation: BMC Cell Biology 2015 16:14

    Content type: Research article

    Published on:

  24. Skeletal muscle differentiation is a multistep, complex pathway in which several important signaling molecules are involved. Recently, microRNAs (miRNAs), endogenous non-coding small RNAs that regulate mRNAs, ...

    Authors: Naoki Katase, Kumiko Terada, Takahiro Suzuki, Shin-ichiro Nishimatsu and Tsutomu Nohno

    Citation: BMC Cell Biology 2015 16:13

    Content type: Research article

    Published on:

    The Erratum to this article has been published in BMC Cell Biology 2016 17:9

  25. Experimental models are inevitably a compromise between accurately reproducing a pathological situation and schematically simplifying it, which is intended to provide both relevance and conclusiveness. In-vivo mo...

    Authors: David Legouis, Aurélien Bataille, Alexandre Hertig, Sophie Vandermeersch, Noémie Simon, Eric Rondeau and Pierre Galichon

    Citation: BMC Cell Biology 2015 16:12

    Content type: Methodology article

    Published on:

  26. The editors of BMC Cell Biology would like to thank all our reviewers who have contributed to the journal in Volume 15 (2014).

    Authors: Tim Sands

    Citation: BMC Cell Biology 2015 16:11

    Content type: Reviewer acknowledgement

    Published on:

  27. In osteoporosis, bone loss is accompanied by increased marrow adiposity. Given their proximity in the bone marrow and their shared origin, a dialogue between adipocytes and osteoblasts could be a factor in the...

    Authors: Perrine J Martin, Nathalie Haren, Olfa Ghali, Aline Clabaut, Christophe Chauveau, Pierre Hardouin and Odile Broux

    Citation: BMC Cell Biology 2015 16:10

    Content type: Research article

    Published on:

  28. Osteoblasts and adipocytes share a common mesenchymal stem cell origin. Therefore, it has been suggested that the accumulation of marrow adipocytes observed in bone loss is caused by a shift in the commitment ...

    Authors: Olfa Ghali, Odile Broux, Guillaume Falgayrac, Nathalie Haren, Johannes PTM van Leeuwen, Guillaume Penel, Pierre Hardouin and Christophe Chauveau

    Citation: BMC Cell Biology 2015 16:9

    Content type: Methodology article

    Published on:

  29. There is evidence that several messenger RNAs (mRNAs) are bifunctional RNAs, i.e. RNA transcript carrying both protein-coding capacity and activity as functional non-coding RNA via 5′ and 3′ untranslated regions ...

    Authors: Hikaru Nagano, Naoko Yamagishi, Chisato Tomida, Chiaki Yano, Kana Aibara, Shohei Kohno, Tomoki Abe, Ayako Ohno, Katsuya Hirasaka, Yuushi Okumura, Edward M Mills, Takeshi Nikawa and Shigetada Teshima-Kondo

    Citation: BMC Cell Biology 2015 16:8

    Content type: Research article

    Published on:

  30. Transforming growth factor-β1 (TGF-β1) plays a key role in mesothelial-to-mesenchymal transition (MMT) during peritoneal dialysis (PD). However, the role of Akt in MMT transformation in PD is not clear.

    Authors: Li Xiao, Xiang Peng, Fuyou Liu, Chengyuan Tang, Chun Hu, Xiaoxuan Xu, Ming Wang, Ying Luo, Shikun Yang, Panai Song, Ping Xiao, Yashpal S Kanwar and Lin Sun

    Citation: BMC Cell Biology 2015 16:7

    Content type: Research article

    Published on:

  31. Mps1, an essential component of the mitotic checkpoint, is also an important interphase regulator and has roles in DNA damage response, cytokinesis and centrosome duplication. Mps1 predominantly resides in the...

    Authors: Haiwei Jia, Xiaojuan Zhang, Wenjun Wang, Yuanyuan Bai, Youguo Ling, Cheng Cao, Runlin Z Ma, Hui Zhong, Xue Wang and Quanbin Xu

    Citation: BMC Cell Biology 2015 16:6

    Content type: Research article

    Published on:

  32. Biosynthetic trafficking of receptors and other membrane-associated proteins from the endoplasmic reticulum (ER) to the plasma membrane (PM) underlies the capacity of these proteins to participate in crucial c...

    Authors: Kirsten L Bryant, Barbara Baird and David Holowka

    Citation: BMC Cell Biology 2015 16:5

    Content type: Methodology article

    Published on:

  33. 3C proteases, the main proteases of picornaviruses, play the key role in viral life cycle by processing polyproteins. In addition, 3C proteases digest certain host cell proteins to suppress antiviral defense, ...

    Authors: Andrey V Shubin, Ilya V Demidyuk, Nataliya A Lunina, Alexey A Komissarov, Marina P Roschina, Olga G Leonova and Sergey V Kostrov

    Citation: BMC Cell Biology 2015 16:4

    Content type: Research article

    Published on:

  34. The growth properties and self-renewal capacity of embryonic stem (ES) cells are regulated by their immediate microenvironment such as the extracellular matrix (ECM). Integrins, a central family of cellular EC...

    Authors: Sandhanakrishnan Cattavarayane, Riitta Palovuori, Jayendrakishore Tanjore Ramanathan and Aki Manninen

    Citation: BMC Cell Biology 2015 16:3

    Content type: Research article

    Published on:

  35. Acacia honey (AH) has been proven to improve skin wound healing, but its therapeutic effects on corneal epithelium has not been elucidated to date. This study aimed to investigate the effects of AH on cultured...

    Authors: Choy Ker-Woon, Norzana Abd Ghafar, Chua Kien Hui, Yasmin Anum Mohd Yusof and Wan Zurinah Wan Ngah

    Citation: BMC Cell Biology 2015 16:2

    Content type: Research article

    Published on:

  36. EDEM1 and EDEM2 are crucial regulators of the endoplasmic reticulum (ER)-associated degradation (ERAD) that extracts misfolded glycoproteins from the calnexin chaperone system. The degradation of ERAD substrat...

    Authors: Iwona Sokołowska, Ewa S Piłka, Kirsten Sandvig, Grzegorz Węgrzyn and Monika Słomińska-Wojewódzka

    Citation: BMC Cell Biology 2015 16:1

    Content type: Research article

    Published on:

  37. Mesenchymal stromal cells (MSC) can be obtained from potentially any tissue from the human body, but cells purified from different sources are undoubtedly different, and for each medical application, the MSC w...

    Authors: Paola Romina Amable, Marcus Vinicius Telles Teixeira, Rosana Bizon Vieira Carias, José Mauro Granjeiro and Radovan Borojevic

    Citation: BMC Cell Biology 2014 15:46

    Content type: Research article

    Published on:

  38. Lipids are stored within cells in lipid droplets (LDs). They consist of a core of neutral lipids surrounded by a monolayer of phospholipids, predominantly phosphatidylcholine (PC). LDs are very dynamic and can...

    Authors: Christine Moessinger, Kristina Klizaite, Almut Steinhagen, Julia Philippou-Massier, Andrej Shevchenko, Michael Hoch, Christer S Ejsing and Christoph Thiele

    Citation: BMC Cell Biology 2014 15:43

    Content type: Research article

    Published on:

  39. With the rapid advancement of cell biology, the evaluation of a given protein’s synthesis and release in cells becomes critical. However, up to now there has been no technique available to morphologically visu...

    Authors: Guowei Huang, Yun Wang, Juping Wang, Chunzhang Yang, Tao Huang, Zhengping Zhuang and Jiang Gu

    Citation: BMC Cell Biology 2014 15:45

    Content type: Methodology article

    Published on:

  40. Basement matrices such as Matrigel™ and Geltrex™ are used in a variety of cell culture assays of anchorage-dependent differentiation including endothelial cell tube formation assays. The volumes of matrix reco...

    Authors: Ashton Faulkner, Robert Purcell, Andrew Hibbert, Sally Latham, Scott Thomson, Wendy L Hall, Caroline Wheeler-Jones and David Bishop-Bailey

    Citation: BMC Cell Biology 2014 15:41

    Content type: Methodology

    Published on:

  41. Surface plasmon resonance imaging (SPRI) is a label-free technique that can image refractive index changes at an interface. We have previously used SPRI to study the dynamics of cell-substratum interactions. H...

    Authors: Alexander W Peterson, Michael Halter, Alessandro Tona and Anne L Plant

    Citation: BMC Cell Biology 2014 15:35

    Content type: Methodology article

    Published on:

  42. Endothelial-mesenchymal transition (EndoMT) has been shown to be a major source of myofibroblasts, contributing to kidney fibrosis. However, in vitro study of endothelial cells often relies on culture of isolated...

    Authors: Ye Zhao, Hong Zhao, Yun Zhang, Tania Tsatralis, Qi Cao, Ya Wang, Yiping Wang, Yuan Min Wang, Steve I Alexander, David C Harris and Guoping Zheng

    Citation: BMC Cell Biology 2014 15:40

    Content type: Methodology article

    Published on:

2018 Journal Metrics

  • Citation Impact

    3.485 - 2-year Impact Factor
    3.227 - 5-year Impact Factor
    0.857 - Source Normalized Impact per Paper (SNIP)
    1.403 - SCImago Journal Rank (SJR)

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