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  1. Myosin IC is a single headed member of the myosin superfamily that localizes to the cytoplasm and the nucleus and is implicated in a variety of processes in both compartments. We recently identified a novel is...

    Authors: Neil L Sielski, Ivanna Ihnatovych, Jacob J Hagen and Wilma A Hofmann

    Citation: BMC Cell Biology 2014 15:8

    Content type: Research article

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  2. Recently, evidence indicated that the rapamycin-eluting stent which was used worldwide may contribute to an increased risk for thrombosis. On the contrary, other researchers found it was safe. Thus, it is nece...

    Authors: Ping Jiang, Yong Lan, Jun Luo, Ya-Li Ren, Dong-Ge Liu, Jian-Xin Pang, Jin Liu, Jian Li, Chen Wang and Jian-Ping Cai

    Citation: BMC Cell Biology 2014 15:7

    Content type: Research article

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  3. Research antibodies are used by thousands of scientists working in diverse disciplines, but it is common to hear concerns about antibody quality. This means that researchers need to carefully choose the antibo...

    Authors: Matthew A Helsby, Paul M Leader, Joe R Fenn, Tulay Gulsen, Chris Bryant, Gail Doughton, Ben Sharpe, Paul Whitley, Christopher J Caunt, Katrina James, Adam D Pope, Dave H Kelly and Andrew D Chalmers

    Citation: BMC Cell Biology 2014 15:6

    Content type: Database

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  4. In the setting of liver injury hepatic progenitor cells are activated, counterbalancing the inhibited regenerative capacity of mature hepatocytes. Chronic activation of this compartment may give rise to a subs...

    Authors: Gianmarco Villano, Cristian Turato, Santina Quarta, Mariagrazia Ruvoletto, Francesco Ciscato, Liliana Terrin, Rossella Semeraro, Claudia Paternostro, Maurizio Parola, Domenico Alvaro, Paolo Bernardi, Angelo Gatta and Patrizia Pontisso

    Citation: BMC Cell Biology 2014 15:5

    Content type: Research article

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  5. The editors of BMC Cell Biology would like to thank all our reviewers who have contributed to the journal in Volume 14 (2013).

    Authors: Tim Sands

    Citation: BMC Cell Biology 2014 15:3

    Content type: Reviewer acknowledgement

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  6. Epigenetic regulation is known to affect gene expression, and recent research shows that aberrant DNA methylation patterning and histone modifications may play a role in leukemogenesis. In order to highlight t...

    Authors: Rūta Navakauskienė, Veronika V Borutinskaitė, Gražina Treigytė, Jūratė Savickienė, Dalius Matuzevičius, Dalius Navakauskas and Karl-Eric Magnusson

    Citation: BMC Cell Biology 2014 15:4

    Content type: Research article

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  7. Reduced muscle mass is a hallmark of metabolic diseases like diabetes and cancer. The mammalian (mechanistic) target of rapamycin complex 1/S6 kinase 1 (mTORC1/S6K1) pathway is critical to the regulation of mu...

    Authors: Dhanshri Kakade, Nushaba Islam, Naomi Maeda and Olasunkanmi A J Adegoke

    Citation: BMC Cell Biology 2014 15:2

    Content type: Research article

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  8. Diabetes and particularly high blood glucose levels are implicated in neurodegeneration. One of the hallmarks of neurodegeneration is protein aggregation. We investigated the presence of protein aggregation in...

    Authors: Fatemeh Talaei, Veroniek M Van Praag, Mahdi H Shishavan, Sjoerd W Landheer, Henk Buikema and Robert H Henning

    Citation: BMC Cell Biology 2014 15:1

    Content type: Research article

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  9. The entry of calcium ions into mammary gland epithelial cells is one of the least well-understood processes in the transport of calcium into milk during lactation. The store-operated calcium entry channel ORAI...

    Authors: Diana GF Ross, Chanel E Smart, Iman Azimi, Sarah J Roberts-Thomson and Gregory R Monteith

    Citation: BMC Cell Biology 2013 14:57

    Content type: Research article

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  10. The Sec61 channel mediates protein translocation across the endoplasmic reticulum (ER) membrane during secretory protein biogenesis, and likely also during export of misfolded proteins for ER-associated degrad...

    Authors: Thomas Tretter, Fábio P Pereira, Ozlem Ulucan, Volkhard Helms, Susanne Allan, Kai-Uwe Kalies and Karin Römisch

    Citation: BMC Cell Biology 2013 14:56

    Content type: Research article

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  11. A good in vitro model should approximate an in vivo-like behavior as closely as possible in order to reflect most likely the in vivo situation. Regarding renal physiology of different species, humans are more clo...

    Authors: Alexandra H Heussner and Daniel R Dietrich

    Citation: BMC Cell Biology 2013 14:55

    Content type: Research article

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  12. Mesenchymal stem cells have properties that make them amenable to therapeutic use. However, the acceptance of mesenchymal stem cells in clinical practice requires standardized techniques for their specific iso...

    Authors: Andrew Wetzig, Ayodele Alaiya, Monther Al-Alwan, Christian Benedict Pradez, Manogaran S Pulicat, Amer Al-Mazrou, Zakia Shinwari, Ghida Majed Sleiman, Hazem Ghebeh, Hind Al-Humaidan, Ameera Gaafar, Imaduddin Kanaan and Chaker Adra

    Citation: BMC Cell Biology 2013 14:54

    Content type: Research article

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  13. Regulation of anoikis in human intestinal epithelial cells (IECs) implicates differentiation state-specific mechanisms. Human IECs express distinct repertoires of integrins according to their state of differen...

    Authors: Marco Beauséjour, Sonya Thibodeau, Marie-Josée Demers, Véronique Bouchard, Rémy Gauthier, Jean-François Beaulieu and Pierre H Vachon

    Citation: BMC Cell Biology 2013 14:53

    Content type: Research article

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  14. BORIS (CTCFL), a paralogue of the multifunctional and ubiquitously expressed transcription factor CTCF, is best known for its role in transcriptional regulation. In the nucleus, BORIS is particularly enriched ...

    Authors: Babatunji W Ogunkolade, Tania A Jones, Johan Aarum, Jaroslaw Szary, Nicholas Owen, Diego Ottaviani, Muhammad A Mumin, Shyam Patel, Christopher A Pieri, Andrew R Silver and Denise Sheer

    Citation: BMC Cell Biology 2013 14:52

    Content type: Research article

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  15. THO (Suppressors of the transcriptional defects of hpr1 delta by overexpression) complex 5 (THOC5), an mRNA export protein, is involved in the expression of only 1% of all genes. Using an interferon inducible ...

    Authors: Shashank Saran, Doan DH Tran, Sabine Klebba-Färber, Patricia Moran-Losada, Lutz Wiehlmann, Alexandra Koch, Himpriya Chopra, Oliver Pabst, Andrea Hoffmann, Robert Klopfleisch and Teruko Tamura

    Citation: BMC Cell Biology 2013 14:51

    Content type: Research article

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  16. Acrosomal proteins play crucial roles in the physiology of fertilization. Identification of proteins localizing to the acrosome is fundamental to the understanding of its contribution to fertilization. Novel p...

    Authors: Rupa Bhattacharya, Manju S Devi, Vishnu M Dhople and Rachel A Jesudasan

    Citation: BMC Cell Biology 2013 14:50

    Content type: Research article

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  17. Integrin α6β4 contributes to cancer progression by stimulating transcription as well as translation of cancer related genes. Our previous study demonstrated that α6β4 stimulates translation initiation of survi...

    Authors: Young Hwa Soung, Nadejda Korneeva, Tae Hyong Kim and Jun Chung

    Citation: BMC Cell Biology 2013 14:49

    Content type: Research article

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  18. Multilineage differentiation, immunomodulation and secretion of trophic factors render mesenchymal stromal cells (MSC) highly attractive for clinical application. Human platelet derivatives such as pooled huma...

    Authors: Sven Kinzebach, Lisa Dietz, Harald Klüter, Hermann-Josef Thierse and Karen Bieback

    Citation: BMC Cell Biology 2013 14:48

    Content type: Research article

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  19. Bone fractures and loss represent significant costs for the public health system and often affect the patients quality of life, therefore, understanding the molecular basis for bone regeneration is essential. ...

    Authors: Erik Halcsik, Maria Fernanda Forni, Andre Fujita, Thiago Verano-Braga, Ole Nørregaard Jensen and Mari Cleide Sogayar

    Citation: BMC Cell Biology 2013 14:47

    Content type: Research article

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  20. Casein Kinase 1 (CK1) is one of few proteins known to affect cellular timekeeping across metazoans, and the naturally occurring CK1tau mutation shortens circadian period in mammals. Functional conservation of a t...

    Authors: Gerben van Ooijen, Sarah F Martin, Martin E Barrios-Llerena, Matthew Hindle, Thierry Le Bihan, John S O'Neill and Andrew J Millar

    Citation: BMC Cell Biology 2013 14:46

    Content type: Research article

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  21. ADF/cofilin proteins are key modulators of actin dynamics in metastasis and invasion of cancer cells. Here we focused on the roles of ADF and cofilin-1 individually in the development of polarized migration of...

    Authors: Lubna H Tahtamouni, Alisa E Shaw, Maram H Hasan, Salem R Yasin and James R Bamburg

    Citation: BMC Cell Biology 2013 14:45

    Content type: Research article

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  22. A few reports suggested that low levels of Wnt signaling might drive cell reprogramming, but these studies could not establish a clear relationship between Wnt signaling and self-renewal networks. There are on...

    Authors: Yue Cheng, Arthur Kwok Leung Cheung, Josephine Mun Yee Ko, Yee Peng Phoon, Pui Man Chiu, Paulisally Hau Yi Lo, Marian L Waterman and Maria Li Lung

    Citation: BMC Cell Biology 2013 14:44

    Content type: Research article

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  23. Fallopian tube secretory epithelial cells (FTSECs) have been implicated as a cell-of-origin for high-grade serous epithelial ovarian cancer. However, there are relatively few in vitro models of this tissue type a...

    Authors: Kate Lawrenson, Maria Notaridou, Nathan Lee, Elizabeth Benjamin, Ian J Jacobs, Christopher Jones and Simon A Gayther

    Citation: BMC Cell Biology 2013 14:43

    Content type: Research article

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  24. Epithelial tissues depend on intercellular homodimerization of E-cadherin and loss of E-cadherin is central to the epithelial to mesenchymal transition seen in multiple human diseases. Signaling pathways regul...

    Authors: Takashi Ohama, Lifu Wang, Erin M Griner and David L Brautigan

    Citation: BMC Cell Biology 2013 14:42

    Content type: Research article

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  25. Increased adipose thermogenesis is being considered as a strategy aimed at preventing or reversing obesity. Thus, regulation of the uncoupling protein 1 (UCP1) gene in human adipocytes is of significant intere...

    Authors: Maria Murholm, Marie S Isidor, Astrid L Basse, Sally Winther, Cathrine Sørensen, Jonas Skovgaard-Petersen, Maja M Nielsen, Aina S Hansen, Bjørn Quistorff and Jacob B Hansen

    Citation: BMC Cell Biology 2013 14:41

    Content type: Research article

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  26. Ischemic preconditioning has been proposed to involve changes in mitochondrial H+ and K+ fluxes, in particular through activation of uncoupling proteins and ATP-sensitive K+ channels (MitoKATP). The objectives of...

    Authors: Saori Morota, Sarah Piel and Magnus J Hansson

    Citation: BMC Cell Biology 2013 14:40

    Content type: Research article

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  27. Differentiation and fusion of skeletal muscle myoblasts into multi-nucleated myotubes is required for neonatal development and regeneration in adult skeletal muscle. Herein, we report novel findings that prote...

    Authors: Joseph S Marino, Terry D Hinds Jr., Rachael A Potter, Eric Ondrus, Jeremy L Onion, Abigail Dowling, Thomas J McLoughlin, Edwin R Sanchez and Jennifer W Hill

    Citation: BMC Cell Biology 2013 14:39

    Content type: Research article

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  28. Angiogenesis is the main therapeutic mechanism of cell therapy for cardiovascular diseases, but diabetes is reported to reduce the function and number of progenitor cells. Therefore, we studied the effect of s...

    Authors: Yong Sook Kim, Jin Sook Kwon, Moon Hwa Hong, Wan Seok Kang, Hye-yun Jeong, Hye-jin Kang, Myung Ho Jeong and Youngkeun Ahn

    Citation: BMC Cell Biology 2013 14:38

    Content type: Research article

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  29. Previous research indicates that the membrane ruffles and leading edge of lamellipodia of myogenic cells contain presumptive fusion sites. A micrometer-sized lipid raft (microraft) is organized at the presumpt...

    Authors: Atsushi Mukai and Naohiro Hashimoto

    Citation: BMC Cell Biology 2013 14:37

    Content type: Research article

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  30. Tissue microenvironments comprise different extracellular matrix (ECM) proteins that regulate cellular responsiveness to growth factors. In vitro culture of adherent cells on ECM-coated substrata is commonly u...

    Authors: Iren Abrahamsen and James B Lorens

    Citation: BMC Cell Biology 2013 14:36

    Content type: Methodology article

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  31. Endolysosomes play a key role in maintaining the homeostasis of the cell. They are made of a complex set of proteins that degrade lipids, proteins and sugars. Studies involving endolysosome contribution to cel...

    Authors: Archana Vaithilingam, Nicole Y Lai, Ellen Duong, Julie Boucau, Yang Xu, Mariko Shimada, Malini Gandhi and Sylvie Le Gall

    Citation: BMC Cell Biology 2013 14:35

    Content type: Methodology article

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  32. Obesity is associated with a higher risk of developing cancer and co-morbidities that are part of the metabolic syndrome. Adipose tissue is recognized as an endocrine organ, as it affects a number of physiolog...

    Authors: Trivia P Frazier, Jeffrey M Gimble, Jessica W Devay, Hugh A Tucker, Ernest S Chiu and Brian G Rowan

    Citation: BMC Cell Biology 2013 14:34

    Content type: Research article

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  33. The transcription factor E2F4 controls proliferation of normal and cancerous intestinal epithelial cells. E2F4 localization in normal human intestinal epithelial cells (HIEC) is cell cycle-dependent, being cyt...

    Authors: Marie-Christine Paquin, Sébastien Cagnol, Julie C Carrier, Caroline Leblanc and Nathalie Rivard

    Citation: BMC Cell Biology 2013 14:33

    Content type: Research article

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  34. Apoptosis is a form of programmed cell death that is regulated by the Bcl-2 family and caspase family of proteins. The caspase cascade responsible for executing cell death following cytochrome c release is well d...

    Authors: Matthew Brentnall, Luis Rodriguez-Menocal, Rebeka Ladron De Guevara, Enrique Cepero and Lawrence H Boise

    Citation: BMC Cell Biology 2013 14:32

    Content type: Research article

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  35. In the progression towards diabetes, glucolipotoxicity is one of the main causes of pancreatic beta cell pathology. The aim of this study was to examine the in vitro effects of chronic glucolipotoxic conditions o...

    Authors: Baggavalli P Somesh, Mahesh Kumar Verma, Manoj Kumar Sadasivuni, Anup Mammen-Oommen, Sanghamitra Biswas, Pavagada C Shilpa, Ashok Kumar Reddy, Aggunda N Yateesh, Puttrevana M Pallavi, Siddaraju Nethra, Rachapalli Smitha, Korrapati Neelima, Usha Narayanan and Madanahalli R Jagannath

    Citation: BMC Cell Biology 2013 14:31

    Content type: Research article

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  36. While the essential role of 3D nuclear architecture on nuclear functions has been demonstrated for various cell types, information available for neutrophils, essential components of the immune system, remains ...

    Authors: Florence Mompart, David Robelin, Chantal Delcros and Martine Yerle-Bouissou

    Citation: BMC Cell Biology 2013 14:30

    Content type: Research article

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  37. Two pathways are responsible for the majority of regulated protein catabolism in eukaryotic cells: the ubiquitin-proteasome system (UPS) and lysosomal self-degradation through autophagy. Both processes are nec...

    Authors: Péter Lőw, Ágnes Varga, Karolina Pircs, Péter Nagy, Zsuzsanna Szatmári, Miklós Sass and Gábor Juhász

    Citation: BMC Cell Biology 2013 14:29

    Content type: Research article

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  38. Renal podocytes form the main filtration barrier possessing a unique phenotype maintained by proteins including podocalyxin and nephrin, the expression of which is suppressed in pathological conditions. We use...

    Authors: Nikolaos E Tsotakos, Marina Sagnou, Eleni S Kotsopoulou, Effie C Tsilibary and Garyfalia I Drossopoulou

    Citation: BMC Cell Biology 2013 14:28

    Content type: Research article

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  39. Autophagy is a conserved cellular process that degrades and recycles cytoplasmic components via a lysosomal pathway. The phosphatidylethanolamine (PE)-conjugation of the Atg8 protein plays an important role in...

    Authors: Chao Liu, Haijie Ma, Jiaxue Wu, Qiang Huang, Jun O Liu and Long Yu

    Citation: BMC Cell Biology 2013 14:27

    Content type: Research article

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  40. H19 is a paternally imprinted gene that has been shown to be highly expressed in the trophoblast tissue. Results from previous studies have initiated a debate as to whether noncoding RNA H19 acts as a tumor suppr...

    Authors: Li-Li Yu, Kai Chang, Lin-Shan Lu, Dan Zhao, Jian Han, Ying-Ru Zheng, Yao-Hua Yan, Ping Yi, Jian-Xin Guo, Yuan-Guo Zhou, Ming Chen and Li Li

    Citation: BMC Cell Biology 2013 14:26

    Content type: Research article

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  41. The extracellular matrix (ECM) influences the structure, viability and functions of cells and tissues. Recent evidence indicates that tumor cells and stromal cells interact through direct cell-cell contact, th...

    Authors: Carolina Meloni Vicente, Ritchelli Ricci, Helena Bonciani Nader and Leny Toma

    Citation: BMC Cell Biology 2013 14:25

    Content type: Research article

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  42. We have recently characterized two distinct populations of Satellite Cells (SCs) that differ in proliferation, regenerative potential, and mitochondrial coupling efficiency and classified these in Low Prolifer...

    Authors: Andrea Repele, Ramona Lupi, Simon Eaton, Luca Urbani, Paolo De Coppi and Michelangelo Campanella

    Citation: BMC Cell Biology 2013 14:24

    Content type: Research article

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  43. The present review summarizes current knowledge about microparticles (MPs) and provides a systematic overview of last 20 years of research on circulating MPs, with particular focus on their clinical relevance.

    Authors: Natasha S Barteneva, Elizaveta Fasler-Kan, Michael Bernimoulin, Joel NH Stern, Eugeny D Ponomarev, Larry Duckett and Ivan A Vorobjev

    Citation: BMC Cell Biology 2013 14:23

    Content type: Review

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  44. Previous studies have implicated continuous or intermittent hyperglycemia in altered endothelium-derived nitric oxide (NO) synthesis. NO can regulate both the F-actin cytoskeleton and endothelial cell membrane...

    Authors: Xianxian Chen, Lie Feng and Hua Jin

    Citation: BMC Cell Biology 2013 14:22

    Content type: Research article

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  45. The scarcity of certain nucleic acid species and the small size of target sequences such as miRNA, impose a significant barrier to subcellular visualization and present a major challenge to cell biologists. He...

    Authors: Kate L Jones, Adam Karpala, Bevan Hirst, Kristie Jenkins, Mark Tizard, Cândida F Pereira, Andrew Leis, Paul Monaghan, Alex Hyatt and Johnson Mak

    Citation: BMC Cell Biology 2013 14:21

    Content type: Methodology article

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  46. Krabbe disease, also known as globoid cell leukodystrophy, is an autosomal recessive neurodegenerative disease caused by the genetic deficiency of galactocerebrosidase (GALC), a lysosomal enzyme responsible fo...

    Authors: Xiujuan Zhang, Julie A Semon, Shijia Zhang, Amy L Strong, Brittni A Scruggs, Jeffrey M Gimble and Bruce A Bunnell

    Citation: BMC Cell Biology 2013 14:20

    Content type: Research article

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  47. Claudins are key integral proteins of the tight junction. Although they play an essential role in controlling paracellular diffusion in epithelia, increasing evidence supports a role for these proteins in non-...

    Authors: Patricia G Webb, Monique A Spillman and Heidi K Baumgartner

    Citation: BMC Cell Biology 2013 14:19

    Content type: Research article

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  48. The objective of this study was to evaluate the effect of bone marrow mesenchymal stem cells (BMSCs) on the apoptosis of granulosa cells (GCs) in rats.

    Authors: Jun-qi Guo, Xia Gao, Zhi-jie Lin, Wei-zhen Wu, Liang-hu Huang, Hui-yue Dong, Jin Chen, Jun Lu, Yun-fen Fu, Jin Wang, Yu-jie Ma, Xiao-wen Chen, Zhi-xian Wu, Fu-qiang He, Shun-liang Yang, Lian-ming Liao…

    Citation: BMC Cell Biology 2013 14:18

    Content type: Research article

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  49. Fibroblasts play a critical role in tumorigenesis, tumor progression and metastasis. However, their detailed molecular characteristics and clinical significance are still elusive. TAGLN is an actin-binding pro...

    Authors: Beiqin Yu, Xuehua Chen, Jianfang Li, Ying Qu, Liping Su, Yibing Peng, Jian Huang, Jun Yan, Yingyan Yu, Qinlong Gu, Zhenggang Zhu and Bingya Liu

    Citation: BMC Cell Biology 2013 14:17

    Content type: Research article

    Published on:

2018 Journal Metrics

  • Citation Impact

    3.485 - 2-year Impact Factor
    3.227 - 5-year Impact Factor
    0.857 - Source Normalized Impact per Paper (SNIP)
    1.403 - SCImago Journal Rank (SJR)

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