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  1. Cellular energy failure in high metabolic rate organs is one of the underlying causes for many disorders such as neurodegenerative diseases, cardiomyopathies, liver and renal failures. In the past decade, nume...

    Authors: Shohreh Majd, John H. T. Power, Timothy K. Chataway and Hugh J. M. Grantham

    Citation: BMC Cell Biology 2018 19:7

    Content type: Research article

    Published on:

  2. Rho guanine exchange factors (RhoGEFs) control cellular processes such as migration, adhesion and proliferation. Alternative splicing of the RhoGEF Trio produces TGAT. The RhoGEF TGAT is an oncoprotein with co...

    Authors: J. van Unen, D. Botman, T. Yin, Y. I. Wu, M. A. Hink, T. W. J. Gadella Jr, M. Postma and J. Goedhart

    Citation: BMC Cell Biology 2018 19:6

    Content type: Research article

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  3. Contactin1 (CNTN1) has been shown to play an important role in the invasion and metastasis of several tumors; however, the role of CNTN1 in breast cancer has not been fully studied. The purpose of this study i...

    Authors: Nan Chen, Sai He, Jie Geng, Zhang-Jun Song, Pi-Hua Han, Juan Qin, Zheng Zhao, Yong-Chun Song, Hu-Xia Wang and Cheng-Xue Dang

    Citation: BMC Cell Biology 2018 19:5

    Content type: Research article

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  4. Mesenchymal stromal cells (MSCs) become an attractive research topic because of their crucial roles in tissue repair and regenerative medicine. Foreskin is considered as a valuable tissue source containing imm...

    Authors: Mehdi Najar, Emerence Crompot, Leo A. van Grunsven, Laurent Dollé and Laurence Lagneaux

    Citation: BMC Cell Biology 2018 19:4

    Content type: Methodology article

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  5. Satellite cells (SC) and their descendants, muscle precursor cells (MPC), play a key role in postnatal muscle development, regeneration, and plasticity. Several studies have provided evidence that SC and MPC r...

    Authors: Claudia Miersch, Katja Stange and Monika Röntgen

    Citation: BMC Cell Biology 2018 19:2

    Content type: Research article

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  6. Globally, rhinitis is one of the most common chronic disorders. Despite availability of drugs to manage the symptomatology of rhinitis, researchers still focus on identification of novel molecular targets for ...

    Authors: Nan Huang, Wenjing Li, Xiaolong Wang and Shanshan Qi

    Citation: BMC Cell Biology 2018 19:1

    Content type: Research article

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  7. Carcinoma associated fibroblasts (CAFs or myofibroblasts) are activated fibroblasts which participate in breast tumor growth, angiogenesis, invasion, metastasis and therapy resistance. As such, recent efforts ...

    Authors: Kathryn Woods, Catlyn Thigpen, Jennifer Peyling Wang, Hana Park and Abigail Hielscher

    Citation: BMC Cell Biology 2017 18:35

    Content type: Research article

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  8. The cell-surface heparan sulfate proteoglycan syndecan-1 is important for tumor cell proliferation, migration, and cell cycle regulation in a broad spectrum of malignancies. Syndecan-1, however, also transloca...

    Authors: Tünde Szatmári, Filip Mundt, Ashish Kumar-Singh, Lena Möbus, Rita Ötvös, Anders Hjerpe and Katalin Dobra

    Citation: BMC Cell Biology 2017 18:34

    Content type: Research article

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  9. Self-renewal and differentiation of embryonic stem cells (ESCs) is directed by biological and/or physical cues that regulate multiple signaling cascades. We have previously shown that mESCs seeded in a type I ...

    Authors: Olesja Hazenbiller, Neil A. Duncan and Roman J. Krawetz

    Citation: BMC Cell Biology 2017 18:32

    Content type: Research article

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  10. Altered expression of mRNA splicing factors occurs with ageing in vivo and is thought to be an ageing mechanism. The accumulation of senescent cells also occurs in vivo with advancing age and causes much degen...

    Authors: Eva Latorre, Vishal C. Birar, Angela N. Sheerin, J. Charles C. Jeynes, Amy Hooper, Helen R. Dawe, David Melzer, Lynne S. Cox, Richard G. A. Faragher, Elizabeth L. Ostler and Lorna W. Harries

    Citation: BMC Cell Biology 2017 18:31

    Content type: Research article

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  11. Generalized methods for understanding the cell biology of non-model species are quite rare, yet very much needed. In order to address this issue, we have modified a technique traditionally used in the biomedic...

    Authors: Benyamin Rosental, Zhanna Kozhekbaeva, Nathaniel Fernhoff, Jonathan M. Tsai and Nikki Traylor-Knowles

    Citation: BMC Cell Biology 2017 18:30

    Content type: Methodology article

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  12. Cartilage degradation is the significant pathological process in osteoarthritis (OA). Inflammatory cytokines, such as interleukin-1β (IL-1β), activate various downstream mediators contributing to OA pathology....

    Authors: Hao Wu, Zhanhai Yin, Ling Wang, Feng Li and Yusheng Qiu

    Citation: BMC Cell Biology 2017 18:29

    Content type: Research article

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  13. Eph signaling is known to induce contrasting cell behaviors such as promoting and inhibiting cell adhesion/spreading by altering F-actin organization and influencing integrin activities. We have previously dem...

    Authors: Midori Mukai, Norihiko Suruga, Noritaka Saeki and Kazushige Ogawa

    Citation: BMC Cell Biology 2017 18:28

    Content type: Research article

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  14. Endophytes have proven to be an invaluable resource of chemically diverse secondary metabolites that act as excellent lead compounds for anticancer drug discovery. Here we report the promising cytotoxic effect...

    Authors: Mytre Koul, Ashok Kumar, Ramesh Deshidi, Vishal Sharma, Rachna D. Singh, Jasvinder Singh, Parduman Raj Sharma, Bhahwal Ali Shah, Sundeep Jaglan and Shashank Singh

    Citation: BMC Cell Biology 2017 18:26

    Content type: Research article

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    The Erratum to this article has been published in BMC Cell Biology 2017 18:27

  15. Staufen2 (STAU2) is an RNA-binding protein involved in the post-transcriptional regulation of gene expression. This protein was shown to be required for organ formation and cell differentiation. Although STAU2...

    Authors: Rémy Beaujois, Elizabeth Ottoni, Xin Zhang, Christina Gagnon, Sami HSine, Stéphanie Mollet, Wildriss Viranaicken and Luc DesGroseillers

    Citation: BMC Cell Biology 2017 18:25

    Content type: Research article

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    The Correction to this article has been published in BMC Cell Biology 2018 19:20

  16. Mesenchymal stem cells (MSCs) are multipotent stromal cells that have the ability to self-renew and migrate to sites of pathology. In vivo tracking of MSCs provides insights into both, the underlying mechanism...

    Authors: Yu Meng, Changzhen Shi, Bo Hu, Jian Gong, Xing Zhong, Xueyin Lin, Xinju Zhang, Jun Liu, Cong Liu and Hao Xu

    Citation: BMC Cell Biology 2017 18:24

    Content type: Research article

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  17. In Dictyostelium discoideum, vesicular transport of the adenylyl cyclase A (ACA) to the posterior of polarized cells is essential to relay exogenous 3′,5′-cyclic

    Authors: Satarupa Das, Joshua M. Parker, Can Guven, Weiye Wang, Paul W. Kriebel, Wolfgang Losert, Daniel R. Larson and Carole A. Parent

    Citation: BMC Cell Biology 2017 18:23

    Content type: Research article

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  18. Autophagy is an inducible autodigestive process that allows cells to recycle proteins and other materials for survival during stress and nutrient deprived conditions. The kinase ULK1 is required to activate th...

    Authors: Wenjia Gan, Caiyun Zhang, Ka Yu Siu, Ayano Satoh, Julian A. Tanner and Sidney Yu

    Citation: BMC Cell Biology 2017 18:22

    Content type: Research Article

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  19. Biomaterials are widely used to regenerate or substitute bone tissue. In order to evaluate their potential use for clinical applications, these need to be tested and evaluated in vitro with cell culture models...

    Authors: Raquel Núñez-Toldrà, Ester Martínez-Sarrà, Carlos Gil-Recio, Miguel Ángel Carrasco, Ashraf Al Madhoun, Sheyla Montori and Maher Atari

    Citation: BMC Cell Biology 2017 18:21

    Content type: Research article

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  20. Obesity is associated with multiple diseases, but it is unclear how obesity promotes progressive tissue damage. Recovery from injury requires repair, an energy-expensive process that is coupled to energy avail...

    Authors: Guanhua Xie, Marzena Swiderska-Syn, Mark L. Jewell, Mariana Verdelho Machado, Gregory A. Michelotti, Richard T. Premont and Anna Mae Diehl

    Citation: BMC Cell Biology 2017 18:20

    Content type: Research article

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  21. External root resorption, commonly starting from cementum, is a severe side effect of orthodontic treatment. In this pathological process and repairing course followed, cementoblasts play a significant role. P...

    Authors: Yuyu Li, Zhiai Hu, Chenchen Zhou, Yang Xu, Li Huang, Xin Wang and Shujuan Zou

    Citation: BMC Cell Biology 2017 18:19

    Content type: Research article

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  22. Environmental stress can affect the viability or fecundity of an organism. Environmental stressors may affect the genome or the proteome and can cause cellular distress by contributing to protein damage or mis...

    Authors: Katherine M. Sampuda, Mason Riley and Lynn Boyd

    Citation: BMC Cell Biology 2017 18:18

    Content type: Research article

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  23. The murine double minute 2 (MDM2) is an oncogene and a negative regulator of the tumor suppressor protein p53. MDM2 is known to be amplified in numerous human cancers, and upregulation of MDM2 is considered to be...

    Authors: Johanna Huun, Liv B. Gansmo, Bård Mannsåker, Gjertrud Titlestad Iversen, Jan Inge Øvrebø, Per E. Lønning and Stian Knappskog

    Citation: BMC Cell Biology 2017 18:17

    Content type: Research article

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  24. In Drosophila early post-meiotic spermatids, mitochondria undergo dramatic shaping into the Nebenkern, a spherical body with complex internal structure that contains two interwrapped giant mitochondrial derivativ...

    Authors: Eric M. Sawyer, Elizabeth C. Brunner, Yihharn Hwang, Lauren E. Ivey, Olivia Brown, Megan Bannon, Dennis Akrobetu, Kelsey E. Sheaffer, Oshauna Morgan, Conroy O. Field, Nishita Suresh, M. Grace Gordon, E. Taylor Gunnell, Lindsay A. Regruto, Cricket G. Wood, Margaret T. Fuller…

    Citation: BMC Cell Biology 2017 18:16

    Content type: Research article

    Published on:

  25. Volumetric muscle loss caused by trauma or after tumour surgery exceeds the natural regeneration capacity of skeletal muscle. Hence, the future goal of tissue engineering (TE) is the replacement and repair of ...

    Authors: R. Witt, A. Weigand, A. M. Boos, A. Cai, D. Dippold, A. R. Boccaccini, D. W. Schubert, M. Hardt, C. Lange, A. Arkudas, R. E. Horch and J. P. Beier

    Citation: BMC Cell Biology 2017 18:15

    Content type: Research article

    Published on:

  26. DNA hypermethylation is a key epigenetic mechanism for the silencing of many genes in cancer. Hinokitiol, a tropolone-related natural compound, is known to induce apoptosis and cell cycle arrest and has anti-i...

    Authors: Jung Seon Seo, Young Ha Choi, Ji Wook Moon, Hyeon Soo Kim and Sun-Hwa Park

    Citation: BMC Cell Biology 2017 18:14

    Content type: Research article

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  27. Cell-based therapy is a treatment method in tendon injuries. Bone morphogenic protein 12 (BMP-12) possesses tenogenic activity and was proposed as a differentiating factor for stem cells directed to transplant...

    Authors: Weronika Zarychta-Wiśniewska, Anna Burdzinska, Agnieszka Kulesza, Kamila Gala, Beata Kaleta, Katarzyna Zielniok, Katarzyna Siennicka, Marek Sabat and Leszek Paczek

    Citation: BMC Cell Biology 2017 18:13

    Content type: Research article

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  28. Dental pulp stem cells (DPSCs) are increasingly being recognized as a viable cell source for regenerative medicine. Although significant variations in their ex vivo expansion are well-established, DPSC prolife...

    Authors: Amr Alraies, Nadia Y. A. Alaidaroos, Rachel J. Waddington, Ryan Moseley and Alastair J. Sloan

    Citation: BMC Cell Biology 2017 18:12

    Content type: Research article

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  29. To cause an economically important blast disease on rice, the filamentous fungus Magnaporthe oryzae forms a specialized infection structure, called an appressorium, to penetrate host cells. Once inside host cells...

    Authors: Emma N. Shipman, Kiersun Jones, Cory B. Jenkinson, Dong Won Kim, Jie Zhu and Chang Hyun Khang

    Citation: BMC Cell Biology 2017 18:11

    Content type: Research article

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  30. Sprouting angiogenesis requires vascular endothelial proliferation, migration and morphogenesis. The process is regulated by soluble factors, principally vascular endothelial growth factor (VEGF), and via bidi...

    Authors: M. Jarad, E. A. Kuczynski, J. Morrison, A. M. Viloria-Petit and B. L. Coomber

    Citation: BMC Cell Biology 2017 18:10

    Content type: Research article

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  31. MicroRNAs are a group of small RNAs that regulate gene expression at the posttranscriptional level. They regulate almost every aspect of cellular processes. In this study, we investigated whether miR-27b regul...

    Authors: Xiangming Zeng, Chaoqun Huang, Lakmini Senavirathna, Pengcheng Wang and Lin Liu

    Citation: BMC Cell Biology 2017 18:9

    Content type: Research article

    Published on:

  32. Obstructive sleep apnea has been linked to the development of heart disease and arrhythmias, including atrial fibrillation. Since altered conduction through gap junction channels can contribute to the pathogen...

    Authors: Joanna Gemel, Zihan Su, Alex Gileles-Hillel, Abdelnaby Khalyfa, David Gozal and Eric C. Beyer

    Citation: BMC Cell Biology 2017 18(Suppl 1):7

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 18 Supplement 1

  33. The lens is an avascular organ composed of an anterior epithelial cell layer and fiber cells that form the bulk of the organ. The lens expresses connexin43 (Cx43), connexin46 (Cx46) and connexin50 (Cx50). Epit...

    Authors: Viviana M. Berthoud and Anaclet Ngezahayo

    Citation: BMC Cell Biology 2017 18(Suppl 1):6

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 18 Supplement 1

  34. Gap junction channels (GJCs) are massive protein channels connecting the cytoplasm of adjacent cells. These channels allow intercellular transfer of molecules up to ~1 kDa, including water, ions and other meta...

    Authors: F. Villanelo, Y. Escalona, C. Pareja-Barrueto, J. A. Garate, I. M. Skerrett and T. Perez-Acle

    Citation: BMC Cell Biology 2017 18(Suppl 1):5

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 18 Supplement 1

  35. Gap junctions are unique membrane channels that play a significant role in intercellular communication in the developing and mature central nervous system (CNS). These channels are composed of connexin protein...

    Authors: Andrei B. Belousov, Joseph D. Fontes, Moises Freitas-Andrade and Christian C. Naus

    Citation: BMC Cell Biology 2017 18(Suppl 1):4

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 18 Supplement 1

  36. This review comes after the International Gap Junction Conference (IGJC 2015) and describes the current knowledge on the function of the specific motifs of connexins in the regulation of the formation of gap j...

    Authors: Thomas Desplantez

    Citation: BMC Cell Biology 2017 18(Suppl 1):3

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 18 Supplement 1

  37. Control of blood flow distribution and tissue homeostasis depend on the tight regulation of and coordination between the microvascular network and circulating blood cells. Channels formed by connexins or panne...

    Authors: Daniela Begandt, Miranda E Good, Alex S. Keller, Leon J. DeLalio, Carol Rowley, Brant E. Isakson and Xavier F. Figueroa

    Citation: BMC Cell Biology 2017 18(Suppl 1):2

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 18 Supplement 1

  38. Nuclear size and shape are specific to a cell type, function, and location, and can serve as indicators of disease and development. We previously found that lamin A/C and associated nuclear envelope structural...

    Authors: Elizabeth R. Smith, Yue Meng, Robert Moore, Jeffrey D. Tse, Arn G. Xu and Xiang-Xi Xu

    Citation: BMC Cell Biology 2017 18:8

    Content type: Research article

    Published on:

  39. Imaging large volumes such as entire cells or small model organisms at nanoscale resolution seemed an unrealistic, rather tedious task so far. Now, technical advances have lead to several electron microscopy (...

    Authors: Irene Wacker, Waldemar Spomer, Andreas Hofmann, Marlene Thaler, Stefan Hillmer, Ulrich Gengenbach and Rasmus R. Schröder

    Citation: BMC Cell Biology 2016 17:38

    Content type: Methodology article

    Published on:

  40. The Cancer Atlas project has shown that p53 is the only commonly (96 %) mutated gene found in high-grade serous epithelial ovarian cancer, the major histological subtype. Another general genetic change is exte...

    Authors: Callinice D. Capo-chichi, Toni M. Yeasky, Elizabeth R. Smith and Xiang-Xi Xu

    Citation: BMC Cell Biology 2016 17:37

    Content type: Research article

    Published on:

    The Erratum to this article has been published in BMC Cell Biology 2017 18:1

  41. To explore the relationship between spatial genome organization and gene expression in the interphase nucleus, we used a genomic imprinting model, which offers parental-specific gene expression. Using 3D FISH ...

    Authors: Yvette Lahbib-Mansais, Harmonie Barasc, Maria Marti-Marimon, Florence Mompart, Eddie Iannuccelli, David Robelin, Juliette Riquet and Martine Yerle-Bouissou

    Citation: BMC Cell Biology 2016 17:35

    Content type: Research article

    Published on:

  42. Mitochondrial dysfunction is one of the leading causes of neurological disorders in humans. Mitochondrial perturbations lead to adaptive mechanisms that include HIF-1 stabilization, though the consequences of ...

    Authors: Muntasir Kamal, Dayana R. D’Amora and Terrance J. Kubiseski

    Citation: BMC Cell Biology 2016 17:34

    Content type: Research article

    Published on:

  43. Genomes of eukaryotes exist as chromatin, and it is known that different chromatin states can influence gene regulation. Chromatin is not a static structure, but is known to be dynamic and vary between cells. ...

    Authors: David Dickerson, Marek Gierliński, Vijender Singh, Etsushi Kitamura, Graeme Ball, Tomoyuki U. Tanaka and Tom Owen-Hughes

    Citation: BMC Cell Biology 2016 17:33

    Content type: Research

    Published on:

2018 Journal Metrics

  • Citation Impact

    3.485 - 2-year Impact Factor
    3.227 - 5-year Impact Factor
    0.857 - Source Normalized Impact per Paper (SNIP)
    1.403 - SCImago Journal Rank (SJR)

    Usage 
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