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  1. Endophytes have proven to be an invaluable resource of chemically diverse secondary metabolites that act as excellent lead compounds for anticancer drug discovery. Here we report the promising cytotoxic effect...

    Authors: Mytre Koul, Ashok Kumar, Ramesh Deshidi, Vishal Sharma, Rachna D. Singh, Jasvinder Singh, Parduman Raj Sharma, Bhahwal Ali Shah, Sundeep Jaglan and Shashank Singh

    Citation: BMC Cell Biology 2017 18:26

    Content type: Research article

    Published on:

    The Erratum to this article has been published in BMC Cell Biology 2017 18:27

  2. Staufen2 (STAU2) is an RNA-binding protein involved in the post-transcriptional regulation of gene expression. This protein was shown to be required for organ formation and cell differentiation. Although STAU2...

    Authors: Rémy Beaujois, Elizabeth Ottoni, Xin Zhang, Christina Gagnon, Sami HSine, Stéphanie Mollet, Wildriss Viranaicken and Luc DesGroseillers

    Citation: BMC Cell Biology 2017 18:25

    Content type: Research article

    Published on:

    The Correction to this article has been published in BMC Cell Biology 2018 19:20

  3. Mesenchymal stem cells (MSCs) are multipotent stromal cells that have the ability to self-renew and migrate to sites of pathology. In vivo tracking of MSCs provides insights into both, the underlying mechanism...

    Authors: Yu Meng, Changzhen Shi, Bo Hu, Jian Gong, Xing Zhong, Xueyin Lin, Xinju Zhang, Jun Liu, Cong Liu and Hao Xu

    Citation: BMC Cell Biology 2017 18:24

    Content type: Research article

    Published on:

  4. In Dictyostelium discoideum, vesicular transport of the adenylyl cyclase A (ACA) to the posterior of polarized cells is essential to relay exogenous 3′,5′-cyclic

    Authors: Satarupa Das, Joshua M. Parker, Can Guven, Weiye Wang, Paul W. Kriebel, Wolfgang Losert, Daniel R. Larson and Carole A. Parent

    Citation: BMC Cell Biology 2017 18:23

    Content type: Research article

    Published on:

  5. Autophagy is an inducible autodigestive process that allows cells to recycle proteins and other materials for survival during stress and nutrient deprived conditions. The kinase ULK1 is required to activate th...

    Authors: Wenjia Gan, Caiyun Zhang, Ka Yu Siu, Ayano Satoh, Julian A. Tanner and Sidney Yu

    Citation: BMC Cell Biology 2017 18:22

    Content type: Research Article

    Published on:

  6. Biomaterials are widely used to regenerate or substitute bone tissue. In order to evaluate their potential use for clinical applications, these need to be tested and evaluated in vitro with cell culture models...

    Authors: Raquel Núñez-Toldrà, Ester Martínez-Sarrà, Carlos Gil-Recio, Miguel Ángel Carrasco, Ashraf Al Madhoun, Sheyla Montori and Maher Atari

    Citation: BMC Cell Biology 2017 18:21

    Content type: Research article

    Published on:

  7. Obesity is associated with multiple diseases, but it is unclear how obesity promotes progressive tissue damage. Recovery from injury requires repair, an energy-expensive process that is coupled to energy avail...

    Authors: Guanhua Xie, Marzena Swiderska-Syn, Mark L. Jewell, Mariana Verdelho Machado, Gregory A. Michelotti, Richard T. Premont and Anna Mae Diehl

    Citation: BMC Cell Biology 2017 18:20

    Content type: Research article

    Published on:

  8. External root resorption, commonly starting from cementum, is a severe side effect of orthodontic treatment. In this pathological process and repairing course followed, cementoblasts play a significant role. P...

    Authors: Yuyu Li, Zhiai Hu, Chenchen Zhou, Yang Xu, Li Huang, Xin Wang and Shujuan Zou

    Citation: BMC Cell Biology 2017 18:19

    Content type: Research article

    Published on:

  9. Environmental stress can affect the viability or fecundity of an organism. Environmental stressors may affect the genome or the proteome and can cause cellular distress by contributing to protein damage or mis...

    Authors: Katherine M. Sampuda, Mason Riley and Lynn Boyd

    Citation: BMC Cell Biology 2017 18:18

    Content type: Research article

    Published on:

  10. The murine double minute 2 (MDM2) is an oncogene and a negative regulator of the tumor suppressor protein p53. MDM2 is known to be amplified in numerous human cancers, and upregulation of MDM2 is considered to be...

    Authors: Johanna Huun, Liv B. Gansmo, Bård Mannsåker, Gjertrud Titlestad Iversen, Jan Inge Øvrebø, Per E. Lønning and Stian Knappskog

    Citation: BMC Cell Biology 2017 18:17

    Content type: Research article

    Published on:

  11. In Drosophila early post-meiotic spermatids, mitochondria undergo dramatic shaping into the Nebenkern, a spherical body with complex internal structure that contains two interwrapped giant mitochondrial derivativ...

    Authors: Eric M. Sawyer, Elizabeth C. Brunner, Yihharn Hwang, Lauren E. Ivey, Olivia Brown, Megan Bannon, Dennis Akrobetu, Kelsey E. Sheaffer, Oshauna Morgan, Conroy O. Field, Nishita Suresh, M. Grace Gordon, E. Taylor Gunnell, Lindsay A. Regruto, Cricket G. Wood, Margaret T. Fuller…

    Citation: BMC Cell Biology 2017 18:16

    Content type: Research article

    Published on:

  12. Volumetric muscle loss caused by trauma or after tumour surgery exceeds the natural regeneration capacity of skeletal muscle. Hence, the future goal of tissue engineering (TE) is the replacement and repair of ...

    Authors: R. Witt, A. Weigand, A. M. Boos, A. Cai, D. Dippold, A. R. Boccaccini, D. W. Schubert, M. Hardt, C. Lange, A. Arkudas, R. E. Horch and J. P. Beier

    Citation: BMC Cell Biology 2017 18:15

    Content type: Research article

    Published on:

  13. DNA hypermethylation is a key epigenetic mechanism for the silencing of many genes in cancer. Hinokitiol, a tropolone-related natural compound, is known to induce apoptosis and cell cycle arrest and has anti-i...

    Authors: Jung Seon Seo, Young Ha Choi, Ji Wook Moon, Hyeon Soo Kim and Sun-Hwa Park

    Citation: BMC Cell Biology 2017 18:14

    Content type: Research article

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  14. Cell-based therapy is a treatment method in tendon injuries. Bone morphogenic protein 12 (BMP-12) possesses tenogenic activity and was proposed as a differentiating factor for stem cells directed to transplant...

    Authors: Weronika Zarychta-Wiśniewska, Anna Burdzinska, Agnieszka Kulesza, Kamila Gala, Beata Kaleta, Katarzyna Zielniok, Katarzyna Siennicka, Marek Sabat and Leszek Paczek

    Citation: BMC Cell Biology 2017 18:13

    Content type: Research article

    Published on:

  15. Dental pulp stem cells (DPSCs) are increasingly being recognized as a viable cell source for regenerative medicine. Although significant variations in their ex vivo expansion are well-established, DPSC prolife...

    Authors: Amr Alraies, Nadia Y. A. Alaidaroos, Rachel J. Waddington, Ryan Moseley and Alastair J. Sloan

    Citation: BMC Cell Biology 2017 18:12

    Content type: Research article

    Published on:

  16. To cause an economically important blast disease on rice, the filamentous fungus Magnaporthe oryzae forms a specialized infection structure, called an appressorium, to penetrate host cells. Once inside host cells...

    Authors: Emma N. Shipman, Kiersun Jones, Cory B. Jenkinson, Dong Won Kim, Jie Zhu and Chang Hyun Khang

    Citation: BMC Cell Biology 2017 18:11

    Content type: Research article

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  17. Sprouting angiogenesis requires vascular endothelial proliferation, migration and morphogenesis. The process is regulated by soluble factors, principally vascular endothelial growth factor (VEGF), and via bidi...

    Authors: M. Jarad, E. A. Kuczynski, J. Morrison, A. M. Viloria-Petit and B. L. Coomber

    Citation: BMC Cell Biology 2017 18:10

    Content type: Research article

    Published on:

  18. MicroRNAs are a group of small RNAs that regulate gene expression at the posttranscriptional level. They regulate almost every aspect of cellular processes. In this study, we investigated whether miR-27b regul...

    Authors: Xiangming Zeng, Chaoqun Huang, Lakmini Senavirathna, Pengcheng Wang and Lin Liu

    Citation: BMC Cell Biology 2017 18:9

    Content type: Research article

    Published on:

  19. Obstructive sleep apnea has been linked to the development of heart disease and arrhythmias, including atrial fibrillation. Since altered conduction through gap junction channels can contribute to the pathogen...

    Authors: Joanna Gemel, Zihan Su, Alex Gileles-Hillel, Abdelnaby Khalyfa, David Gozal and Eric C. Beyer

    Citation: BMC Cell Biology 2017 18(Suppl 1):7

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 18 Supplement 1

  20. The lens is an avascular organ composed of an anterior epithelial cell layer and fiber cells that form the bulk of the organ. The lens expresses connexin43 (Cx43), connexin46 (Cx46) and connexin50 (Cx50). Epit...

    Authors: Viviana M. Berthoud and Anaclet Ngezahayo

    Citation: BMC Cell Biology 2017 18(Suppl 1):6

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 18 Supplement 1

  21. Gap junction channels (GJCs) are massive protein channels connecting the cytoplasm of adjacent cells. These channels allow intercellular transfer of molecules up to ~1 kDa, including water, ions and other meta...

    Authors: F. Villanelo, Y. Escalona, C. Pareja-Barrueto, J. A. Garate, I. M. Skerrett and T. Perez-Acle

    Citation: BMC Cell Biology 2017 18(Suppl 1):5

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 18 Supplement 1

  22. Gap junctions are unique membrane channels that play a significant role in intercellular communication in the developing and mature central nervous system (CNS). These channels are composed of connexin protein...

    Authors: Andrei B. Belousov, Joseph D. Fontes, Moises Freitas-Andrade and Christian C. Naus

    Citation: BMC Cell Biology 2017 18(Suppl 1):4

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 18 Supplement 1

  23. This review comes after the International Gap Junction Conference (IGJC 2015) and describes the current knowledge on the function of the specific motifs of connexins in the regulation of the formation of gap j...

    Authors: Thomas Desplantez

    Citation: BMC Cell Biology 2017 18(Suppl 1):3

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 18 Supplement 1

  24. Control of blood flow distribution and tissue homeostasis depend on the tight regulation of and coordination between the microvascular network and circulating blood cells. Channels formed by connexins or panne...

    Authors: Daniela Begandt, Miranda E Good, Alex S. Keller, Leon J. DeLalio, Carol Rowley, Brant E. Isakson and Xavier F. Figueroa

    Citation: BMC Cell Biology 2017 18(Suppl 1):2

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 18 Supplement 1

  25. Nuclear size and shape are specific to a cell type, function, and location, and can serve as indicators of disease and development. We previously found that lamin A/C and associated nuclear envelope structural...

    Authors: Elizabeth R. Smith, Yue Meng, Robert Moore, Jeffrey D. Tse, Arn G. Xu and Xiang-Xi Xu

    Citation: BMC Cell Biology 2017 18:8

    Content type: Research article

    Published on:

  26. Imaging large volumes such as entire cells or small model organisms at nanoscale resolution seemed an unrealistic, rather tedious task so far. Now, technical advances have lead to several electron microscopy (...

    Authors: Irene Wacker, Waldemar Spomer, Andreas Hofmann, Marlene Thaler, Stefan Hillmer, Ulrich Gengenbach and Rasmus R. Schröder

    Citation: BMC Cell Biology 2016 17:38

    Content type: Methodology article

    Published on:

  27. The Cancer Atlas project has shown that p53 is the only commonly (96 %) mutated gene found in high-grade serous epithelial ovarian cancer, the major histological subtype. Another general genetic change is exte...

    Authors: Callinice D. Capo-chichi, Toni M. Yeasky, Elizabeth R. Smith and Xiang-Xi Xu

    Citation: BMC Cell Biology 2016 17:37

    Content type: Research article

    Published on:

    The Erratum to this article has been published in BMC Cell Biology 2017 18:1

  28. To explore the relationship between spatial genome organization and gene expression in the interphase nucleus, we used a genomic imprinting model, which offers parental-specific gene expression. Using 3D FISH ...

    Authors: Yvette Lahbib-Mansais, Harmonie Barasc, Maria Marti-Marimon, Florence Mompart, Eddie Iannuccelli, David Robelin, Juliette Riquet and Martine Yerle-Bouissou

    Citation: BMC Cell Biology 2016 17:35

    Content type: Research article

    Published on:

  29. Mitochondrial dysfunction is one of the leading causes of neurological disorders in humans. Mitochondrial perturbations lead to adaptive mechanisms that include HIF-1 stabilization, though the consequences of ...

    Authors: Muntasir Kamal, Dayana R. D’Amora and Terrance J. Kubiseski

    Citation: BMC Cell Biology 2016 17:34

    Content type: Research article

    Published on:

  30. Genomes of eukaryotes exist as chromatin, and it is known that different chromatin states can influence gene regulation. Chromatin is not a static structure, but is known to be dynamic and vary between cells. ...

    Authors: David Dickerson, Marek Gierliński, Vijender Singh, Etsushi Kitamura, Graeme Ball, Tomoyuki U. Tanaka and Tom Owen-Hughes

    Citation: BMC Cell Biology 2016 17:33

    Content type: Research

    Published on:

  31. Formins are a highly conserved family of cytoskeletal remodeling proteins. A growing body of evidence suggests that formins play key roles in the progression and spread of a variety of cancers. There are 15 hu...

    Authors: Christine Péladeau, Allan Heibein, Melissa T. Maltez, Sarah J. Copeland and John W. Copeland

    Citation: BMC Cell Biology 2016 17:32

    Content type: Research article

    Published on:

  32. The serine/threonine kinase PAK1 is an important regulator of cell motility. Both PAK1 and the hormone/cytokine prolactin (PRL) have been implicated in breast cancer cell motility, however, the exact mechanism...

    Authors: Alan Hammer and Maria Diakonova

    Citation: BMC Cell Biology 2016 17:31

    Content type: Research article

    Published on:

  33. Karyotypic integrity is essential for the successful germline transmission of alleles mutated in embryonic stem (ES) cells. Classical methods for the identification of aneuploidy involve cytological analyses t...

    Authors: Gemma F. Codner, Loic Lindner, Adam Caulder, Marie Wattenhofer-Donzé, Adam Radage, Annelyse Mertz, Benjamin Eisenmann, Joffrey Mianné, Edward P. Evans, Colin V. Beechey, Martin D. Fray, Marie-Christine Birling, Yann Hérault, Guillaume Pavlovic and Lydia Teboul

    Citation: BMC Cell Biology 2016 17:30

    Content type: Methodology article

    Published on:

  34. Antigenic stimulation of the T cell receptor (TCR) initiates a change from a resting state into an activated one, which ultimately results in proliferation and the acquisition of effector functions. To accompl...

    Authors: Clemens Cammann, Alexander Rath, Udo Reichl, Holger Lingel, Monika Brunner-Weinzierl, Luca Simeoni, Burkhart Schraven and Jonathan A. Lindquist

    Citation: BMC Cell Biology 2016 17:28

    Content type: Research article

    Published on:

  35. Vacuolar-type proton pumps help maintain acid–base homeostasis either within intracellular compartments or at specialised plasma membranes. In mammals they are made up of 13 subunits, which form two functional...

    Authors: Zoe J. Golder and Fiona E. Karet Frankl

    Citation: BMC Cell Biology 2016 17:27

    Content type: Research article

    Published on:

  36. Nesprin-1-giant (1008kD) is a protein of the outer nuclear membrane that links nuclei to the actin cytoskeleton via amino-terminal calponin homology domains. The short nesprin-1 isoform, nesprin-1-α2, is prese...

    Authors: Ian Holt, Nguyen Thuy Duong, Qiuping Zhang, Le Thanh Lam, Caroline A. Sewry, Kamel Mamchaoui, Catherine M. Shanahan and Glenn E. Morris

    Citation: BMC Cell Biology 2016 17:26

    Content type: Research article

    Published on:

  37. Vascular endothelial dysfunction is the closely related determinant of ischemic heart disease (IHD). Endothelial dysfunction and ischemia/reperfusion injury (IRI) have been associated with an increase in micro...

    Authors: Qi Zhang, Man Shang, Mengxiao Zhang, Yao Wang, Yan Chen, Yanna Wu, Minglin Liu, Junqiu Song and Yanxia Liu

    Citation: BMC Cell Biology 2016 17:25

    Content type: Research article

    Published on:

  38. Flagella and cilia are fine thread-like organelles protruding from cells that harbour them. The typical ‘9 + 2’ cilia confer motility on these cells. Although the mechanistic details of motility remain elusive...

    Authors: Venkatramanan G. Rao, Ruhi B. Sarafdar, Twinkle S. Chowdhury, Priyanka Sivadas, Pinfen Yang, Prabhakar M. Dongre and Jacinta S. D’Souza

    Citation: BMC Cell Biology 2016 17:24

    Content type: Research article

    Published on:

  39. Ankyrin repeats and LEM domain containing protein 1 (Ankle1) belongs to the LEM protein family, whose members share a chromatin-interacting LEM motif. Unlike most other LEM proteins, Ankle1 is not an integral ...

    Authors: Livija Zlopasa, Andreas Brachner and Roland Foisner

    Citation: BMC Cell Biology 2016 17:23

    Content type: Research article

    Published on:

  40. Internalization of gap junction plaques results in the formation of annular gap junction vesicles. The factors that regulate the coordinated internalization of the gap junction plaques to form annular gap junc...

    Authors: Matthias M. Falk, Cheryl L. Bell, Rachael M. Kells Andrews and Sandra A. Murray

    Citation: BMC Cell Biology 2016 17(Suppl 1):S22

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  41. Connexins mediate intercellular communication by assembling into hexameric channel complexes that act as hemichannels and gap junction channels. Most connexins are characterized by a very rapid turn-over in a ...

    Authors: Jegan Iyyathurai, Jean-Paul Decuypere, Luc Leybaert, Catheleyne D’hondt and Geert Bultynck

    Citation: BMC Cell Biology 2016 17(Suppl 1):S20

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  42. Electron micrographs revealed the presence of gap junctions in osteoblastic cells over 40 years ago. These intercellular channels formed from connexins are present in bone forming osteoblasts, bone resorbing o...

    Authors: Lilian I. Plotkin, Dale W. Laird and Joelle Amedee

    Citation: BMC Cell Biology 2016 17(Suppl 1):S19

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  43. Mutations in human connexin (Cx) genes have been related to diseases, which we termed connexinopathies. Such hereditary disorders include nonsyndromic or syndromic deafness (Cx26, Cx30), Charcot Marie Tooth di...

    Authors: Isaac E. García, Pavel Prado, Amaury Pupo, Oscar Jara, Diana Rojas-Gómez, Paula Mujica, Carolina Flores-Muñoz, Jorge González-Casanova, Carolina Soto-Riveros, Bernardo I. Pinto, Mauricio A. Retamal, Carlos González and Agustín D. Martínez

    Citation: BMC Cell Biology 2016 17(Suppl 1):S17

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  44. Mutations in the gene encoding for dysferlin cause recessive autosomal muscular dystrophies called dysferlinopathies. These mutations induce several alterations in skeletal muscles, including, inflammation, in...

    Authors: Luis A. Cea, Jorge A. Bevilacqua, Christian Arriagada, Ana María Cárdenas, Anne Bigot, Vincent Mouly, Juan C. Sáez and Pablo Caviedes

    Citation: BMC Cell Biology 2016 17(Suppl 1):15

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  45. Communication among cells via direct cell-cell contact by connexin gap junctions, or between cell and extracellular environment via pannexin channels or connexin hemichannels, is a key factor in cell function ...

    Authors: Jean X. Jiang and Silvia Penuela

    Citation: BMC Cell Biology 2016 17(Suppl 1):S12

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

  46. Connexins and pannexins share very similar structures and functions; they also exhibit overlapping expression in many stages of neuronal development. Here, we review evidence implicating connexin- and pannexin...

    Authors: Leigh Anne Swayne and Steffany A. L. Bennett

    Citation: BMC Cell Biology 2016 17(Suppl 1):S10

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 17 Supplement 1

2018 Journal Metrics

  • Citation Impact

    3.485 - 2-year Impact Factor
    3.227 - 5-year Impact Factor
    0.857 - Source Normalized Impact per Paper (SNIP)
    1.403 - SCImago Journal Rank (SJR)

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