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  1. Previously published reports indicated that some enzymes of the central carbon metabolism (CCM), particularly those involved in glycolysis and the tricarboxylic acid cycle, may contribute to regulation of DNA ...

    Authors: Aleksandra Konieczna, Aneta Szczepańska, Karolina Sawiuk, Grzegorz Węgrzyn and Robert Łyżeń

    Citation: BMC Cell Biology 2015 16:16

    Content type: Research article

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  2. Polycystin-1 (PC-1) is a large plasma membrane receptor, encoded by the PKD1 gene, which is mutated in most cases of Autosomal Dominant Polycystic Kidney Disease (ADPKD). The disease is characterized by renal cys...

    Authors: Maddalena Castelli, Chiara De Pascalis, Gianfranco Distefano, Nadia Ducano, Amanda Oldani, Letizia Lanzetti and Alessandra Boletta

    Citation: BMC Cell Biology 2015 16:15

    Content type: Research article

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  3. Optineurin is a gene associated with normal tension glaucoma and amyotrophic lateral sclerosis. It has been reported previously that in cultured RGC5 cells, the turnover of endogenous optineurin involves mainl...

    Authors: Hongyu Ying, Sanja Turturro, Tara Nguyen, Xiang Shen, Ruth Zelkha, Elaine C Johnson, John C Morrison and Beatrice YJT Yue

    Citation: BMC Cell Biology 2015 16:14

    Content type: Research article

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  4. Skeletal muscle differentiation is a multistep, complex pathway in which several important signaling molecules are involved. Recently, microRNAs (miRNAs), endogenous non-coding small RNAs that regulate mRNAs, ...

    Authors: Naoki Katase, Kumiko Terada, Takahiro Suzuki, Shin-ichiro Nishimatsu and Tsutomu Nohno

    Citation: BMC Cell Biology 2015 16:13

    Content type: Research article

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    The Erratum to this article has been published in BMC Cell Biology 2016 17:9

  5. Experimental models are inevitably a compromise between accurately reproducing a pathological situation and schematically simplifying it, which is intended to provide both relevance and conclusiveness. In-vivo mo...

    Authors: David Legouis, Aurélien Bataille, Alexandre Hertig, Sophie Vandermeersch, Noémie Simon, Eric Rondeau and Pierre Galichon

    Citation: BMC Cell Biology 2015 16:12

    Content type: Methodology article

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  6. The editors of BMC Cell Biology would like to thank all our reviewers who have contributed to the journal in Volume 15 (2014).

    Authors: Tim Sands

    Citation: BMC Cell Biology 2015 16:11

    Content type: Reviewer acknowledgement

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  7. In osteoporosis, bone loss is accompanied by increased marrow adiposity. Given their proximity in the bone marrow and their shared origin, a dialogue between adipocytes and osteoblasts could be a factor in the...

    Authors: Perrine J Martin, Nathalie Haren, Olfa Ghali, Aline Clabaut, Christophe Chauveau, Pierre Hardouin and Odile Broux

    Citation: BMC Cell Biology 2015 16:10

    Content type: Research article

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  8. Osteoblasts and adipocytes share a common mesenchymal stem cell origin. Therefore, it has been suggested that the accumulation of marrow adipocytes observed in bone loss is caused by a shift in the commitment ...

    Authors: Olfa Ghali, Odile Broux, Guillaume Falgayrac, Nathalie Haren, Johannes PTM van Leeuwen, Guillaume Penel, Pierre Hardouin and Christophe Chauveau

    Citation: BMC Cell Biology 2015 16:9

    Content type: Methodology article

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  9. There is evidence that several messenger RNAs (mRNAs) are bifunctional RNAs, i.e. RNA transcript carrying both protein-coding capacity and activity as functional non-coding RNA via 5′ and 3′ untranslated regions ...

    Authors: Hikaru Nagano, Naoko Yamagishi, Chisato Tomida, Chiaki Yano, Kana Aibara, Shohei Kohno, Tomoki Abe, Ayako Ohno, Katsuya Hirasaka, Yuushi Okumura, Edward M Mills, Takeshi Nikawa and Shigetada Teshima-Kondo

    Citation: BMC Cell Biology 2015 16:8

    Content type: Research article

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  10. Transforming growth factor-β1 (TGF-β1) plays a key role in mesothelial-to-mesenchymal transition (MMT) during peritoneal dialysis (PD). However, the role of Akt in MMT transformation in PD is not clear.

    Authors: Li Xiao, Xiang Peng, Fuyou Liu, Chengyuan Tang, Chun Hu, Xiaoxuan Xu, Ming Wang, Ying Luo, Shikun Yang, Panai Song, Ping Xiao, Yashpal S Kanwar and Lin Sun

    Citation: BMC Cell Biology 2015 16:7

    Content type: Research article

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  11. Mps1, an essential component of the mitotic checkpoint, is also an important interphase regulator and has roles in DNA damage response, cytokinesis and centrosome duplication. Mps1 predominantly resides in the...

    Authors: Haiwei Jia, Xiaojuan Zhang, Wenjun Wang, Yuanyuan Bai, Youguo Ling, Cheng Cao, Runlin Z Ma, Hui Zhong, Xue Wang and Quanbin Xu

    Citation: BMC Cell Biology 2015 16:6

    Content type: Research article

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  12. Biosynthetic trafficking of receptors and other membrane-associated proteins from the endoplasmic reticulum (ER) to the plasma membrane (PM) underlies the capacity of these proteins to participate in crucial c...

    Authors: Kirsten L Bryant, Barbara Baird and David Holowka

    Citation: BMC Cell Biology 2015 16:5

    Content type: Methodology article

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  13. 3C proteases, the main proteases of picornaviruses, play the key role in viral life cycle by processing polyproteins. In addition, 3C proteases digest certain host cell proteins to suppress antiviral defense, ...

    Authors: Andrey V Shubin, Ilya V Demidyuk, Nataliya A Lunina, Alexey A Komissarov, Marina P Roschina, Olga G Leonova and Sergey V Kostrov

    Citation: BMC Cell Biology 2015 16:4

    Content type: Research article

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  14. The growth properties and self-renewal capacity of embryonic stem (ES) cells are regulated by their immediate microenvironment such as the extracellular matrix (ECM). Integrins, a central family of cellular EC...

    Authors: Sandhanakrishnan Cattavarayane, Riitta Palovuori, Jayendrakishore Tanjore Ramanathan and Aki Manninen

    Citation: BMC Cell Biology 2015 16:3

    Content type: Research article

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  15. Acacia honey (AH) has been proven to improve skin wound healing, but its therapeutic effects on corneal epithelium has not been elucidated to date. This study aimed to investigate the effects of AH on cultured...

    Authors: Choy Ker-Woon, Norzana Abd Ghafar, Chua Kien Hui, Yasmin Anum Mohd Yusof and Wan Zurinah Wan Ngah

    Citation: BMC Cell Biology 2015 16:2

    Content type: Research article

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  16. EDEM1 and EDEM2 are crucial regulators of the endoplasmic reticulum (ER)-associated degradation (ERAD) that extracts misfolded glycoproteins from the calnexin chaperone system. The degradation of ERAD substrat...

    Authors: Iwona Sokołowska, Ewa S Piłka, Kirsten Sandvig, Grzegorz Węgrzyn and Monika Słomińska-Wojewódzka

    Citation: BMC Cell Biology 2015 16:1

    Content type: Research article

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  17. Mesenchymal stromal cells (MSC) can be obtained from potentially any tissue from the human body, but cells purified from different sources are undoubtedly different, and for each medical application, the MSC w...

    Authors: Paola Romina Amable, Marcus Vinicius Telles Teixeira, Rosana Bizon Vieira Carias, José Mauro Granjeiro and Radovan Borojevic

    Citation: BMC Cell Biology 2014 15:46

    Content type: Research article

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  18. Lipids are stored within cells in lipid droplets (LDs). They consist of a core of neutral lipids surrounded by a monolayer of phospholipids, predominantly phosphatidylcholine (PC). LDs are very dynamic and can...

    Authors: Christine Moessinger, Kristina Klizaite, Almut Steinhagen, Julia Philippou-Massier, Andrej Shevchenko, Michael Hoch, Christer S Ejsing and Christoph Thiele

    Citation: BMC Cell Biology 2014 15:43

    Content type: Research article

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  19. With the rapid advancement of cell biology, the evaluation of a given protein’s synthesis and release in cells becomes critical. However, up to now there has been no technique available to morphologically visu...

    Authors: Guowei Huang, Yun Wang, Juping Wang, Chunzhang Yang, Tao Huang, Zhengping Zhuang and Jiang Gu

    Citation: BMC Cell Biology 2014 15:45

    Content type: Methodology article

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  20. Basement matrices such as Matrigel™ and Geltrex™ are used in a variety of cell culture assays of anchorage-dependent differentiation including endothelial cell tube formation assays. The volumes of matrix reco...

    Authors: Ashton Faulkner, Robert Purcell, Andrew Hibbert, Sally Latham, Scott Thomson, Wendy L Hall, Caroline Wheeler-Jones and David Bishop-Bailey

    Citation: BMC Cell Biology 2014 15:41

    Content type: Methodology

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  21. Surface plasmon resonance imaging (SPRI) is a label-free technique that can image refractive index changes at an interface. We have previously used SPRI to study the dynamics of cell-substratum interactions. H...

    Authors: Alexander W Peterson, Michael Halter, Alessandro Tona and Anne L Plant

    Citation: BMC Cell Biology 2014 15:35

    Content type: Methodology article

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  22. Cnidarians are the closest living relatives to bilaterians and have been instrumental to studying the evolution of bilaterian properties. The cnidarian model, Nematostella vectensis, is a unique system in which e...

    Authors: Timothy Q DuBuc, Anna A Dattoli, Leslie S Babonis, Miguel Salinas-Saavedra, Eric Röttinger, Mark Q Martindale and Marten Postma

    Citation: BMC Cell Biology 2014 15:44

    Content type: Methodology article

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  23. Endothelial-mesenchymal transition (EndoMT) has been shown to be a major source of myofibroblasts, contributing to kidney fibrosis. However, in vitro study of endothelial cells often relies on culture of isolated...

    Authors: Ye Zhao, Hong Zhao, Yun Zhang, Tania Tsatralis, Qi Cao, Ya Wang, Yiping Wang, Yuan Min Wang, Steve I Alexander, David C Harris and Guoping Zheng

    Citation: BMC Cell Biology 2014 15:40

    Content type: Methodology article

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  24. Mesenchymal stem cells (MSCs) have the potential to differentiate into specialized cell lineages such as osteoblasts and adipocytes in vitro. There exists a reciprocal relationship between osteogenic and adipogen...

    Authors: Sooho Lee, Hee-Yeon Cho, Hang Thi Thuy Bui and Dongchul Kang

    Citation: BMC Cell Biology 2014 15:42

    Content type: Research article

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  25. Neutrophils are a critical part of the innate immune system. Their ability to migrate into infected or injured tissues precedes their role in microbial killing and clearance. We have previously shown that Rab2...

    Authors: Rajesh K Singh, Rebecca C Furze, Mark A Birrell, Sara M Rankin, Alistair N Hume and Miguel C Seabra

    Citation: BMC Cell Biology 2014 15:39

    Content type: Research article

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  26. The interleukin-8 chemokine (IL-8) G-protein coupled receptor CXCR2 governs pro-inflammatory and pro-angiogenic responses in leukocytes and endothelial cells. At a molecular standpoint, CXCR2 is widely reporte...

    Authors: Héloise M Leclair, Sonia M Dubois, Sandy Azzi, Julie Dwyer, Nicolas Bidère and Julie Gavard

    Citation: BMC Cell Biology 2014 15:38

    Content type: Research article

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  27. Resistance to chemotherapy represents a major obstacle in correcting colorectal carcinomas (CRC). Inspite of recent advances in the treatment of metastatic disease, the prognosis of the patients remains poor. ...

    Authors: Asif Khurshid Qazi, Aashiq Hussain, Mushtaq A Aga, Shakir Ali, Subhash Chandra Taneja, Parduman Raj Sharma, Ajit Kumar Saxena, Dilip M Mondhe and Abid Hamid

    Citation: BMC Cell Biology 2014 15:36

    Content type: Research article

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  28. The bone marrow is a hematopoietic tissue that, in the presence of cytokines and growth factors, generates all of the circulating blood cells. These cells are important for protecting the organism against path...

    Authors: Bruno José Martins da Silva, Ana Paula D Rodrigues, Luis Henrique S Farias, Amanda Anastácia P Hage, Jose Luiz M Do Nascimento and Edilene O Silva

    Citation: BMC Cell Biology 2014 15:37

    Content type: Research article

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  29. The expression of 2′-5′-Oligoadenylate synthetases (OASs) is induced by type 1 Interferons (IFNs) in response to viral infection. The OAS proteins have a unique ability to produce 2′-5′ Oligoadenylates, which ...

    Authors: Karina Hansen Kjær, Jytte Pahus, Mariann Fagernæs Hansen, Jesper Buchhave Poulsen, Erik Ilsø Christensen, Just Justesen and Pia Møller Martensen

    Citation: BMC Cell Biology 2014 15:33

    Content type: Research article

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  30. In mammalian cells, ASPL is involved in insulin-stimulated redistribution of the glucose transporter GLUT4 and assembly of the Golgi apparatus. Its putative yeast orthologue, Ubx4, is important for proteasome ...

    Authors: Louise Madsen, Karen Molbæk, Ida B Larsen, Sofie V Nielsen, Esben G Poulsen, Peter S Walmod, Kay Hofmann, Michael Seeger, Chen-Ying Chien, Rey-Huei Chen, Franziska Kriegenburg and Rasmus Hartmann-Petersen

    Citation: BMC Cell Biology 2014 15:31

    Content type: Research article

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  31. The Akita mutation (C96Y) in the insulin gene results in early onset diabetes in both humans and mice. Expression of mutant proinsulin (C96Y) causes endoplasmic reticulum (ER) stress in pancreatic β-cells and ...

    Authors: Liling Zhang, Courtney Nosak, Pietro Sollazzo, Tanya Odisho and Allen Volchuk

    Citation: BMC Cell Biology 2014 15:29

    Content type: Research article

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  32. Cullins belong to a family of scaffold proteins that assemble multi-subunit ubiquitin ligase complexes to recruit protein substrates for ubiquitination via unique sets of substrate adaptor, such as Skp1 or Elo...

    Authors: Wananit Wimuttisuk, Mark West, Brittney Davidge, Kebing Yu, Arthur Salomon and Jeffrey D Singer

    Citation: BMC Cell Biology 2014 15:28

    Content type: Research article

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  33. The visceral musculature of Drosophila larvae comprises circular visceral muscles tightly interwoven with longitudinal visceral muscles. During myogenesis, the circular muscles arise by one-to-one fusion of a cir...

    Authors: Anja Rudolf, Detlev Buttgereit, Matthias Jacobs, Georg Wolfstetter, Dörthe Kesper, Michael Pütz, Susanne Berger, Renate Renkawitz-Pohl, Anne Holz and Susanne F Önel

    Citation: BMC Cell Biology 2014 15:27

    Content type: Research article

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  34. Live cell imaging enables the study of dynamic processes of living cells in real time by use of suitable reporter proteins and the staining of specific cellular structures and/or organelles. With the availabil...

    Authors: Sandeep Salipalli, Prafull Kumar Singh and Jürgen Borlak

    Citation: BMC Cell Biology 2014 15:26

    Content type: Review

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  35. Nuclear Dbf-related/large tumor suppressor (NDR/LATS) kinases have been shown recently to control pathways that regulate mitotic exit, cytokinesis, cell growth, morphological changes and apoptosis. LATS kinase...

    Authors: Annette Müller-Taubenberger, Peter M Kastner, Michael Schleicher, Parvin Bolourani and Gerald Weeks

    Citation: BMC Cell Biology 2014 15:25

    Content type: Research article

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  36. Chronic inflammation-mediated β-cell apoptosis is known to decrease β-cell mass in diabetes leading to reduced insulin secretion. Exposure to pro-inflammatory cytokines can stimulate apoptosis in pancreatic β-...

    Authors: Mahesh Kumar Verma, Manoj Kumar Sadasivuni, Aggunda N Yateesh, Korrapati Neelima, Srikanth Mrudula, Madhusudhan Reddy, Rachapalli Smitha, Sanghamitra Biswas, Bhawna Chandravanshi, Puttrevana M Pallavi, Anup M Oommen, Madanahalli R Jagannath and Baggavalli P Somesh

    Citation: BMC Cell Biology 2014 15:24

    Content type: Research article

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  37. Clathrin-mediated vesicular trafficking, the mechanism by which proteins and lipids are transported between membrane-bound organelles, accounts for a large proportion of import from the plasma membrane (endocy...

    Authors: Ligia Cristina Kalb, Yohana Camila Antunes Frederico, Cassiano Martin Batista, Iriane Eger, Stênio Perdigão Fragoso and Maurilio José Soares

    Citation: BMC Cell Biology 2014 15:23

    Content type: Research article

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  38. Characterizing the nuclear orientation of chromosomes in the three-dimensional (3D) nucleus by multicolor banding (mBANDing) is a new approach towards understanding nuclear organization of chromosome territori...

    Authors: Ann-Kristin Schmälter, Alexandra Kuzyk, Christiaan H Righolt, Michaela Neusser, Ortrud K Steinlein, Stefan Müller and Sabine Mai

    Citation: BMC Cell Biology 2014 15:22

    Content type: Research article

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  39. Upon activation neutrophil releases microparticles - small plasma membrane vesicles that contain cell surface proteins and cytoplasmic matter, with biological activities. In this study we investigated the pote...

    Authors: Thassila Nogueira Pitanga, Luciana de Aragão França, Viviane Costa Junqueira Rocha, Thayna Meirelles, Valéria Matos Borges, Marilda Souza Gonçalves, Lain Carlos Pontes-de-Carvalho, Alberto Augusto Noronha-Dutra and Washington Luis Conrado dos-Santos

    Citation: BMC Cell Biology 2014 15:21

    Content type: Research article

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  40. Normal, healthy human breast tissue from a variety of volunteer donors has become available for research thanks to the establishment of the Susan G. Komen for the Cure® Tissue Bank at the IU Simon Cancer Cente...

    Authors: Candice AM Sauder, Jillian E Koziel, MiRan Choi, Melanie J Fox, Brenda R Grimes, Sunil Badve, Rachel J Blosser, Milan Radovich, Christina C Lam, Melville B Vaughan, Brittney-Shea Herbert and Susan E Clare

    Citation: BMC Cell Biology 2014 15:20

    Content type: Research article

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  41. Acacia honey is a natural product which has proven to have therapeutic effects on skin wound healing, but its potential healing effects in corneal wound healing have not been studied. This study aimed to explo...

    Authors: Choy Ker-Woon, Norzana Abd Ghafar, Chua Kien Hui and Yasmin Anum Mohd Yusof

    Citation: BMC Cell Biology 2014 15:19

    Content type: Research article

    Published on:

  42. Polycomb Group (PcG) proteins are chromatin modifiers involved in early embryonic development as well as in proliferation of adult stem cells and cancer cells. PcG proteins form large repressive complexes term...

    Authors: Prasad Pethe, Punam Nagvenkar and Deepa Bhartiya

    Citation: BMC Cell Biology 2014 15:18

    Content type: Research article

    Published on:

  43. Telomeres have crucial meiosis-specific roles in the orderly reduction of chromosome numbers and in ensuring the integrity of the genome during meiosis. One such role is the attachment of telomeres to trans-nu...

    Authors: Katrin Daniel, Daniel Tränkner, Lukasz Wojtasz, Hiroki Shibuya, Yoshinori Watanabe, Manfred Alsheimer and Attila Tóth

    Citation: BMC Cell Biology 2014 15:17

    Content type: Research article

    Published on:

  44. Fibroblast Activation Protein alpha (FAP-α) or seprase is an integral membrane serine peptidase. Previous work has not satisfactorily explained both the suppression and promotion effects that have been observe...

    Authors: Jun Jia, Tracey Amanda Martin, Lin Ye and Wen Guo Jiang

    Citation: BMC Cell Biology 2014 15:16

    Content type: Research article

    Published on:

  45. The domestic pig is an excellent animal model to study human microbial diseases due to its similarity to humans in terms of anatomy, physiology, and genetics. We assessed the suitability of an in vitro air-liquid...

    Authors: Mario Delgado-Ortega, Michel Olivier, Pierre-Yves Sizaret, Gaëlle Simon and François Meurens

    Citation: BMC Cell Biology 2014 15:14

    Content type: Methodology article

    Published on:

2018 Journal Metrics

  • Citation Impact

    3.485 - 2-year Impact Factor
    3.227 - 5-year Impact Factor
    0.857 - Source Normalized Impact per Paper (SNIP)
    1.403 - SCImago Journal Rank (SJR)

    Usage 
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