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Table 1 Cytotoxic activity of INA-UV treatment measured on different cancer cell lines by the MTS assay

From: Photo-activation of the hydrophobic probe iodonaphthylazide in cells alters membrane protein function leading to cell death

Cell line Human cancer types IC50 ± SE (μM)*
MCF7 Breast adenocarcinoma 20.6 ± 8.8
HeLa Cervical cancer 11.2 ± 1.7
U251 Glioma 15.4 ± 1.0
SKOV-3 Ovarian carcinoma 17.6 ± 1.0
SKBR-3 Breast carcinoma 7.8 ± 1.5
KB3-1 Epidermoid carcinoma 16.0 ± 0.7
KBV1 Epidermoid carcinoma overexpressing Pgp 12.3 ± 4.4
293 Epithelial cell line from embryonic kidney 8.6 ± 0.9
293/MRP1 Epithelial cell line from embryonic kidney overexpressing MRP1 7.3 ± 1.0
SupT1 T lymphoblastoid 4.9 ± 0.6
  1. * Seven independent measurements were performed and analyzed together. IC50 values were computed by fitting a four-parameter nonlinear regression model with R statistical software [57]. The standard error (SE) represents the 95% confidence interval.