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  1. Content type: Research article

    Docking large ligands, and especially peptides, to protein receptors is still considered a challenge in computational structural biology. Besides the issue of accurately scoring the binding modes of a protein-...

    Authors: Didier Devaurs, Dinler A Antunes, Sarah Hall-Swan, Nicole Mitchell, Mark Moll, Gregory Lizée and Lydia E Kavraki

    Citation: BMC Molecular and Cell Biology 2019 20:42

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  2. Content type: Research article

    Microtubule proteins are able to produce electromagnetic fields and have an important role in memory formation, and learning. Therefore, microtubules have the potential to be affected by exogenous electromagne...

    Authors: Dariush Gholami, Gholamhossein Riazi, Rouhollah Fathi, Mohsen Sharafi and Abdolhossein Shahverdi

    Citation: BMC Molecular and Cell Biology 2019 20:41

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  3. Content type: Research article

    The essentially unlimited expansion potential and the pluripotency of human embryonic stem cells (hESCs) make them attractive for cell-based therapeutic purposes. Although hESCs can indefinitely proliferate in...

    Authors: Guillermo A. Videla-Richardson, Verónica A. Furmento, Carolina P. Garcia, Olivia Morris-Hanon, Gustavo E. Sevlever, Leonardo Romorini and María E. Scassa

    Citation: BMC Molecular and Cell Biology 2019 20:40

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  4. Content type: Research article

    A study has shown that miR-423-5p is highly expressed in proliferative diabetic retinopathy. However, the exact biological functions and mechanisms of miR-423-5p in diabetic retinopathy (DR) progression are cu...

    Authors: Qing Xiao, Yinu Zhao, Jia Xu, Wen-Jie Li, Yu Chen and Hong-Jing Sun

    Citation: BMC Molecular and Cell Biology 2019 20:39

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  5. Content type: Research article

    The EP4 prostanoid receptor is one of four GPCRs that mediate the diverse actions of prostaglandin E2 (PGE2). Novel selective EP4 receptor agonists would assist to further elucidate receptor sub-type function and...

    Authors: Melissa C. Holt, Chi S. Ho, M. Inés Morano, Stephen D. Barrett and Adam J. Stein

    Citation: BMC Molecular and Cell Biology 2019 20:37

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  6. Content type: Research article

    Whole-proteome distributions of protein isoelectric point (pI) values in different organisms are bi- or trimodal with some variations. It was suggested that the observed multimodality of the proteome-wide pI d...

    Authors: Atsushi Kurotani, Alexander A. Tokmakov, Ken-Ichi Sato, Vasily E. Stefanov, Yutaka Yamada and Tetsuya Sakurai

    Citation: BMC Molecular and Cell Biology 2019 20:36

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  7. Content type: Research article

    HPV16 infection is one of the main risk factors involved in the development of cervical cancer, mainly due to the high oncogenic potential of the viral proteins E6 and E7, which are involved in the different p...

    Authors: Hugo Alberto Rodríguez-Ruiz, Olga Lilia Garibay-Cerdenares, Berenice Illades-Aguiar, Sarita Montaño, Xiaowei Jiang and Marco Antonio Leyva-Vázquez

    Citation: BMC Molecular and Cell Biology 2019 20:35

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  8. Content type: Research article

    The PINK1:Parkin pathway regulates the autophagic removal of damaged and dysfunctional mitochondria. While the response of this pathway to complete loss of ΔΨm, as caused by high concentrations of mitochondria...

    Authors: J. Logan Bowling, Mary Catherine Skolfield, Wesley A. Riley, Andrew P. Nolin, Larissa C. Wolf and David E. Nelson

    Citation: BMC Molecular and Cell Biology 2019 20:33

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  9. Content type: Methodology article

    Endothelial cells (ECs) play a key role in tissue homeostasis, in several pathological conditions, and specifically in the control of vascular functions. ECs are frequently used as in vitro model systems for c...

    Authors: Olli-Pekka A. Hätinen, Johanna E. Lähteenvuo, Henna J. Korpela, Juho J. Pajula and Seppo Ylä-Herttuala

    Citation: BMC Molecular and Cell Biology 2019 20:32

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  10. Content type: Research article

    The discovery of thermostable DNA polymerases such as Taq DNA polymerase revolutionized amplification of DNA by polymerase chain reaction methods that rely on thermal cycling for strand separation. These metho...

    Authors: Yvonne Piotrowski, Man Kumari Gurung and Atle Noralf Larsen

    Citation: BMC Molecular and Cell Biology 2019 20:31

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  11. Content type: Research article

    Several human cancers, especially cervical cancer are caused by the infection of high risk strains of human papillomaviruses (HPV), notably HPV16. It is implicated that the oncoprotein E6 expressed from HPV, i...

    Authors: Srikanth Kolluru, Rosemary Momoh, Lydia Lin, Jayapal Reddy Mallareddy and John L. Krstenansky

    Citation: BMC Molecular and Cell Biology 2019 20:30

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  12. Content type: Research article

    CD40 is a 48 kDa type I transmembrane protein that is constitutively expressed on hematopoietic cells such as dendritic cells, macrophages, and B cells. Engagement of CD40 by CD40L expressed on T cells results...

    Authors: Maria A. Argiriadi, Lorenzo Benatuil, Ievgeniia Dubrovska, David A. Egan, Lei Gao, Amy Greischar, Jennifer Hardman, John Harlan, Ramesh B. Iyer, Russell A. Judge, Marc Lake, Denise C. Perron, Ramkrishna Sadhukhan, Bernhard Sielaff, Silvino Sousa, Rui Wang…

    Citation: BMC Molecular and Cell Biology 2019 20:29

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  13. Content type: Research article

    Metabolites are genetically and environmentally determined. Consequently, they can be used to characterize environmental exposures and reveal biochemical mechanisms that link exposure to disease. To explore di...

    Authors: Aida Santaolalla, Hans Garmo, Anita Grigoriadis, Sundeep Ghuman, Niklas Hammar, Ingmar Jungner, Göran Walldius, Mats Lambe, Lars Holmberg and Mieke Van Hemelrijck

    Citation: BMC Molecular and Cell Biology 2019 20:28

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  14. Content type: Research article

    Podocyte plays an important role in maintaining the integrity and function of the glomerular filtration barrier. Various studies reported that forkhead transcription factor (Fox) O1 played a key role in anti-o...

    Authors: Hongkun Wang, Yanhui Zhang, Fangfang Xia, Wei Zhang, Peng Chen and Guoan Yang

    Citation: BMC Molecular and Cell Biology 2019 20:27

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  15. Content type: Research article

    Cardiac stem cells (CSCs) exhibit age-dependent characteristics. Cited2 has been implicated in the regulation of heart development; however, there is little known about how Cited2 affects CSC aging.

    Authors: Qiong Wu, Qin Liu, Jinxi Zhan, Qian Wang, Daxiu Zhang, Shuangli He, Shiming Pu and Zuping Zhou

    Citation: BMC Molecular and Cell Biology 2019 20:25

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  16. Content type: Publisher Correction

    During production of the original article [1], there was a technical error that resulted in author corrections not being rendered in the PDF version of the article.

    Authors: Gera A. Pavlova, Alyona V. Razuvaeva, Julia V. Popova, Evgeniya N. Andreyeva, Lyubov A. Yarinich, Mikhail O. Lebedev, Claudia Pellacani, Silvia Bonaccorsi, Maria Patrizia Somma, Maurizio Gatti and Alexey V. Pindyurin

    Citation: BMC Molecular and Cell Biology 2019 20:24

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    The original article was published in BMC Molecular and Cell Biology 2019 20:7

  17. Content type: Research article

    Protein tyrosine phosphatase PTPN13, also known as PTP-BL in mice, is a large multi-domain non-transmembrane scaffolding protein with a molecular mass of 270 kDa. It is involved in the regulation of several ce...

    Authors: Markus Dicks, Gerd Kock, Bastian Kohl, Xueyin Zhong, Stefanie Pütz, Rolf Heumann, Kai S. Erdmann and Raphael Stoll

    Citation: BMC Molecular and Cell Biology 2019 20:23

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  18. Content type: Research article

    Wntless (Wls) is a protein that regulates secretion of Wnt signaling molecules from Wnt-producing cells. Wnt signaling is known to be critical for several developmental and homeostatic processes. However, Wnt-...

    Authors: Jessica Petko, Mathura Thileepan, Molly Sargen, Victor Canfield and Robert Levenson

    Citation: BMC Molecular and Cell Biology 2019 20:22

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  19. Content type: Research article

    To-date, no claim regarding finding a consensus sequon for O-glycosylation has been made. Thus, predicting the likelihood of O-glycosylation with sequence and structural information using classical regression ana...

    Authors: Rajaram Gana and Sona Vasudevan

    Citation: BMC Molecular and Cell Biology 2019 20:21

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  20. Content type: Research article

    Classic dendritic cells (cDCs) play a central role in the immune system by processing and presenting antigens to activate T cells, and consist of two major subsets: CD141+ cDC (cDC1) and CD1c+ cDC (cDC2). A popul...

    Authors: Wenji Ma, Jaeyop Lee, Daniel Backenroth, Yu Jerry Zhou, Erin Bush, Peter Sims, Kang Liu and Yufeng Shen

    Citation: BMC Molecular and Cell Biology 2019 20:20

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  21. Content type: Research article

    CG4552/tbc1 was identified as a downstream target of Fork head (Fkh), the single Drosophila member of the FoxA family of transcription factors and a major player in salivary gland formation and homeostasis. Tbc1 ...

    Authors: Dorothy M. Johnson and Deborah J. Andrew

    Citation: BMC Molecular and Cell Biology 2019 20:19

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  22. Content type: Database

    The manual classification of protein domains is approaching its 20th anniversary. ECOD is our mixed manual-automatic domain classification. Over time, the types of proteins which require manual curation has ch...

    Authors: R. Dustin Schaeffer, Lisa Kinch, Kirill E. Medvedev, Jimin Pei, Hua Cheng and Nick Grishin

    Citation: BMC Molecular and Cell Biology 2019 20:18

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  23. Content type: Research article

    The forkhead transcription factor (FOXL2) plays a crucial role in blepharophimosis-ptosis-epicanthus inversus syndrome (BPES), sex determination, ovary growth and development, and cell cycle regulation. Emergi...

    Authors: Yangyang Han, Jun Wu, Weiwei Yang, Di Wang, Tianliang Zhang and Min Cheng

    Citation: BMC Molecular and Cell Biology 2019 20:17

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  24. Content type: Research article

    Colon cancer affects 1.23 million people worldwide and is the third most common malignant disease in men and the second in women. The only curative treatment is surgical resection, but a significant number of ...

    Authors: D. Yonar, A. Kılıç Süloğlu, G. Selmanoğlu and M. M. Sünnetçioğlu

    Citation: BMC Molecular and Cell Biology 2019 20:16

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  25. Content type: Research article

    To investigate the effects of serum amyloid A1 (SAA1) on lipopolysaccharide (LPS) -induced inflammation in vascular smooth muscle cells (VSMCs). SAA1 expression was detected in LPS induced VSMCs at different c...

    Authors: Mei-Hong Yu, Xi Li, Qian Li, Shi-Jing Mo, Yin Ni, Fang Han, Yi-Bin Wang and Yue-Xing Tu

    Citation: BMC Molecular and Cell Biology 2019 20:15

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  26. Content type: Research article

    Hypertrophic cardiomyopathy occurs along with pathological phenomena such as cardiac hypertrophy, myocardial fibrosis and cardiomyocyte activity. However, few of the specific molecular mechanisms underlying th...

    Authors: Xin Liu, Lin Lin, Qing Li, Yajuan Ni, Chaoying Zhang, Shuguang Qin and Jin Wei

    Citation: BMC Molecular and Cell Biology 2019 20:14

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  27. Content type: Research article

    Cesium-137 (137Cs) is one of the major and most clinically relevant radionuclides of concern in a radiological dispersal device, “dirty bomb” scenario as well as in nuclear accidents and detonations. In this expo...

    Authors: Helen C. Turner, Younghyun Lee, Waylon Weber, Dunstana Melo, Aimee Kowell, Shanaz A. Ghandhi, Sally A. Amundson, David J. Brenner and Igor Shuryak

    Citation: BMC Molecular and Cell Biology 2019 20:13

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  28. Content type: Research article

    MicroRNAs (miRNAs) are increasingly being identified as modulatory molecules for physiological and pathological processes in muscle. Here, we investigated whether miRNAs influenced the expression of the stress...

    Authors: Bilal A. Mir, Rabia Islam, Ming Kalanon, Aaron P. Russell and Victoria C. Foletta

    Citation: BMC Molecular and Cell Biology 2019 20:12

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  29. Content type: Research article

    Nuclear lamins are type V intermediate filament proteins that maintain nuclear structure and function. Furthermore, Emerin - an interactor of Lamin A/C, facilitates crosstalk between the cytoskeleton and the n...

    Authors: Devika Ranade, Roopali Pradhan, Muhunden Jayakrishnan, Sushmitha Hegde and Kundan Sengupta

    Citation: BMC Molecular and Cell Biology 2019 20:11

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  30. Content type: Research article

    Focal Adhesion Kinase (FAK) is a major cancer drug target that is involved in numerous aspects of tumor progression and survival. While multiple research groups have developed ATP-competitive small molecule in...

    Authors: Timothy Marlowe, Alexey Dementiev, Sheila Figel, Andrew Rivera, Michael Flavin and William Cance

    Citation: BMC Molecular and Cell Biology 2019 20:10

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  31. Content type: Research

    The calmodulin-regulated spectrin-associated proteins (CAMSAPs) belong to a conserved protein family, which includes members that bind the polymerizing mcrotubule (MT) minus ends and remain associated with the...

    Authors: Gera A. Pavlova, Alyona V. Razuvaeva, Julia V. Popova, Evgeniya N. Andreyeva, Lyubov A. Yarinich, Mikhail O. Lebedev, Claudia Pellacani, Silvia Bonaccorsi, Maria Patrizia Somma, Maurizio Gatti and Alexey V. Pindyurin

    Citation: BMC Molecular and Cell Biology 2019 20(Suppl 1):7

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    This article is part of a Supplement: Volume 20 Supplement 1

    The Publisher Correction to this article has been published in BMC Molecular and Cell Biology 2019 20:24

  32. Content type: Research article

    Dlx5 and Dlx6 stimulate differentiation of diverse progenitors during embryonic development. Their actions as pro-differentiation transcription factors includes the up-regulation of differentiation markers but th...

    Authors: Rachel K. MacKenzie, Parvathy Ravi Sankar and Andrew J. Bendall

    Citation: BMC Molecular and Cell Biology 2019 20:8

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  33. Content type: Research article

    Osteoclasts play a critical role in bone resorption due to orthodontic tooth movement (OTM). In OTM, a force is exerted on the tooth, creating compression of the periodontal ligament (PDL) on one side of the t...

    Authors: Hiroyuki Kanzaki, Satoshi Wada, Yuuki Yamaguchi, Yuta Katsumata, Kanako Itohiya, Sari Fukaya, Yutaka Miyamoto, Tsuyoshi Narimiya, Koji Noda and Yoshiki Nakamura

    Citation: BMC Molecular and Cell Biology 2019 20:6

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  34. Content type: Research article

    Dental follicle cells (DFCs) are dental stem cells and interesting options for regenerative therapies in dentistry. However, DFCs acquire replicative senescence in long-term cultures, but little is known about...

    Authors: Christian Morsczeck, Anja Reck and Torsten E. Reichert

    Citation: BMC Molecular and Cell Biology 2019 20:5

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  35. Content type: Research article

    The white coat colour of Yorkshire and Landrace pig breeds is caused by the dominant white I allele of KIT, associated with 450-kb duplications and a splice mutation (G > A) at the first base in intron 17. To tes...

    Authors: Ke Qin, Xinyu Liang, Guanjie Sun, Xuan Shi, Min Wang, Hongbo Liu, Yaosheng Chen, Xiaohong Liu and Zuyong He

    Citation: BMC Molecular and Cell Biology 2019 20:4

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  36. Content type: Research article

    Egg formation takes place in the oviduct of laying hens over a 24 h period. Infectious bronchitis virus (IBV) causes pathological lesions in the chicken oviduct. In the current study, mitochondrial counts were...

    Authors: Samiullah Khan, Juliet Roberts and Shu-Biao Wu

    Citation: BMC Molecular and Cell Biology 2019 20:3

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  37. Content type: Research article

    Extrachromosomal acentric double minutes (DMs) contribute to human malignancy by carrying amplified oncogenes. Recent cancer genomics revealed that the pulverization of defined chromosome arms (chromothripsis)...

    Authors: Noriaki Shimizu, Rita Kapoor, Shuhei Naniwa, Naoto Sakamaru, Taku Yamada, You-ki Yamamura and Koh-ichi Utani

    Citation: BMC Molecular and Cell Biology 2019 20:2

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  38. Content type: Research article

    The conserved NDR-family kinase Sid2p localizes to the contractile ring during fission yeast cytokinesis to promote ring constriction, septation, and completion of cell division. Previous studies have found th...

    Authors: Lois Kwon, Emma M. Magee, Alexis Crayton and John W. Goss

    Citation: BMC Molecular and Cell Biology 2019 20:1

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  39. Content type: Research article

    Diapause is a form of dormancy that is genetically predetermined to allow animals to overcome harsh environmental conditions. It is induced by predictive environmental cues bringing cellular activity levels in...

    Authors: Luxi Chen, Rosemary E. Barnett, Martin Horstmann, Verena Bamberger, Lea Heberle, Nina Krebs, John K. Colbourne, Rocío Gómez and Linda C. Weiss

    Citation: BMC Cell Biology 2018 19:30

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  40. Content type: Research article

    TRAIL, tumor necrosis factor-related apoptosis-inducing ligand, can selectively kill cancer cells with little or no cytotoxicity toward normal human cells and is regarded as a potential relatively safe antitum...

    Authors: Zhi Lan Guo, Jing Zhe Li, Yan Yan Ma, Dan Qian, Ju Ying Zhong, Meng Meng Jin, Peng Huang, Lu Yang Che, Bing Pan, Yi Wang, Zhen Xiao Sun and Chang Zhen Liu

    Citation: BMC Cell Biology 2018 19:29

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  41. Content type: Research article

    Dasatinib (Sprycel) was developed as a tyrosine kinase inhibitor targeting Bcr-Abl and the family of Src kinases. Dasatinib is commonly used for the treatment of acute lymphoblastic and chronic myelogenous leu...

    Authors: Josip Skoko, Jan Rožanc, Emilie M. Charles, Leonidas G. Alexopoulos and Markus Rehm

    Citation: BMC Cell Biology 2018 19:28

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  42. Content type: Research article

    Within the past years, umbilical cord (UC) and amniotic membrane (AM) expanded in human platelet lysate (PL) have been found to become increasingly candidate of mesenchymal stromal cells (MSCs) in preclinical ...

    Authors: Yongxu Mu, Xiaoyun Wu and Zhiming Hao

    Citation: BMC Cell Biology 2018 19:27

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  43. Content type: Research article

    Endothelial cells provide a barrier between blood and tissues, which is regulated to allow molecules and cells in out of tissues. Patients with cerebral cavernous malformations (CCM) have dilated leaky blood v...

    Authors: Narendra Suryavanshi, Joanna Furmston and Anne J. Ridley

    Citation: BMC Cell Biology 2018 19:26

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  44. Content type: Research article

    KIF17, a kinesin-2 motor that functions in intraflagellar transport, can regulate the onset of photoreceptor outer segment development. However, the function of KIF17 in a mature photoreceptor remains unclear....

    Authors: Tylor R. Lewis, Sean R. Kundinger, Brian A. Link, Christine Insinna and Joseph C. Besharse

    Citation: BMC Cell Biology 2018 19:25

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  45. Content type: Research article

    Myocardial ischemia-reperfusion injury (IRI) has become one of the most serious complications after reperfusion therapy in patients with acute myocardial infarction. Small ubiquitin-like modification (SUMOylat...

    Authors: Bo Xie, Xinyu Liu, Jie Yang, Jinke Cheng, Jianmin Gu and Song Xue

    Citation: BMC Cell Biology 2018 19:24

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  46. Content type: Research article

    Disruption to the blood brain barrier (BBB) is a leading factor associated with the development of postoperative cognitive dysfunction (POCD). Despite this, the underlying mechanism by which BBB disruption pro...

    Authors: Honghua Zhu, Wei Liu and Hao Fang

    Citation: BMC Cell Biology 2018 19:23

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2018 Journal Metrics

  • Citation Impact

    3.485 - 2-year Impact Factor
    3.227 - 5-year Impact Factor
    0.857 - Source Normalized Impact per Paper (SNIP)
    1.403 - SCImago Journal Rank (SJR)