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  2. Schwann cells (SCs) play a crucial role in the repair of peripheral nerves. This is due to their ability to proliferate, migrate, and provide trophic support to axon regrowth. During peripheral nerve injury, S...

    Authors: Zhenghui Cheng, Yawen Zhang, Yinchao Tian, Yuhan Chen, Fei Ding, Han Wu, Yuhua Ji and Mi Shen

    Citation: BMC Molecular and Cell Biology 2021 22:21

    Content type: Research article

    Published on:

  3. Bioinformatic genome surveys indicate that self-cleaving ribonucleic acids (ribozymes) appear to be widespread among all domains of life, although the functions of only a small number have been validated by bi...

    Authors: Aiyada Aroonsri, Jindaporn Kongsee, Jeremy David Gunawan, Daniel Abidin Aubry and Philip James Shaw

    Citation: BMC Molecular and Cell Biology 2021 22:20

    Content type: Methodology article

    Published on:

  4. The asthma-related airway wall remodeling is associated i.a. with a damage of bronchial epithelium and subepithelial fibrosis. Functional interactions between human bronchial epithelial cells and human bronchi...

    Authors: Milena Paw, Dawid Wnuk, Bogdan Jakieła, Grażyna Bochenek, Krzysztof Sładek, Zbigniew Madeja and Marta Michalik

    Citation: BMC Molecular and Cell Biology 2021 22:19

    Content type: Research article

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  5. Reef-building corals regularly experience changes in intra- and extracellular H+ concentrations ([H+]) due to physiological and environmental processes. Stringent control of [H+] is required to maintain the homeo...

    Authors: Laura Capasso, Philippe Ganot, Víctor Planas-Bielsa, Sylvie Tambutté and Didier Zoccola

    Citation: BMC Molecular and Cell Biology 2021 22:18

    Content type: Research article

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  6. Surface plasmon resonance is a label-free biophysical technique that is widely used in investigating biomolecular interactions, including protein-protein, protein-DNA, and protein-small molecule binding. Surfa...

    Authors: Purushottam B. Tiwari, Camelia Bencheqroun, Mario Lemus, Taryn Shaw, Marilyn Kouassi-Brou, Adil Alaoui and Aykut Üren

    Citation: BMC Molecular and Cell Biology 2021 22:17

    Content type: Database

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  7. Staufen2 (STAU2) is an RNA binding protein involved in the posttranscriptional regulation of gene expression. In neurons, STAU2 is required to maintain the balance between differentiation and proliferation of ...

    Authors: Lionel Condé, Yulemi Gonzalez Quesada, Florence Bonnet-Magnaval, Rémy Beaujois and Luc DesGroseillers

    Citation: BMC Molecular and Cell Biology 2021 22:16

    Content type: Research article

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  8. Previously, we revealed sexually dimorphic mRNA expression and responsiveness to maternal dietary supplementation with n-3 long-chain polyunsaturated fatty acids (LCPUFA) in placentas from a defined INFAT stud...

    Authors: Eva-Maria Sedlmeier, Dorothy M. Meyer, Lynne Stecher, Manuela Sailer, Hannelore Daniel, Hans Hauner and Bernhard L. Bader

    Citation: BMC Molecular and Cell Biology 2021 22:15

    Content type: Research article

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  9. An amendment to this paper has been published and can be accessed via the original article.

    Authors: J. Gautron, L. Stapane, N. Le Roy, Y. Nys, A. B. Rodriguez-Navarro and M. T. Hincke

    Citation: BMC Molecular and Cell Biology 2021 22:14

    Content type: Correction

    Published on:

    The original article was published in BMC Molecular and Cell Biology 2021 22:11

  10. Human induced pluripotent stem cells (iPSC) have opened new avenues for regenerative medicine. Consequently, iPSC-derived motor neurons have emerged as potentially viable therapies for spinal cord injuries and...

    Authors: Emilia Solomon, Katie Davis-Anderson, Blake Hovde, Sofiya Micheva-Viteva, Jennifer Foster Harris, Scott Twary and Rashi Iyer

    Citation: BMC Molecular and Cell Biology 2021 22:13

    Content type: Research article

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  11. Enterocytes exert an absorptive and protective function in the intestine, and they encounter many different challenging factors such as feed, bacteria, and parasites. An intestinal epithelial in vitro model ca...

    Authors: Federico Ghiselli, Barbara Rossi, Martina Felici, Maria Parigi, Giovanni Tosi, Laura Fiorentini, Paola Massi, Andrea Piva and Ester Grilli

    Citation: BMC Molecular and Cell Biology 2021 22:12

    Content type: Methodology article

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  12. The avian eggshell is a natural protective envelope that relies on the phenomenon of biomineralization for its formation. The shell is made of calcium carbonate in the form of calcite, which contains hundreds ...

    Authors: J. Gautron, L. Stapane, N. Le Roy, Y. Nys, A. B. Rodriguez-Navarro and M. T. Hincke

    Citation: BMC Molecular and Cell Biology 2021 22:11

    Content type: Review

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    The Correction to this article has been published in BMC Molecular and Cell Biology 2021 22:14

  13. Musashi1 (MSI1) is an oncogenic protein with a crucial role in the proliferation and characteristics of the epithelial cells in breast cancer. The change in expression of MSI1 has a role in solid tumor progressio...

    Authors: Mahboobeh Forouzanfar, Liana Lachinani, Kianoush Dormiani, Mohammad Hossein Nasr-Esfahani and Kamran Ghaedi

    Citation: BMC Molecular and Cell Biology 2021 22:10

    Content type: Research article

    Published on:

  15. Warts, hypogammaglobulinemia, recurrent bacterial infections and myelokathexis (WHIM) syndrome is a primary immunodeficiency disease (PID) usually caused by autosomal dominant mutations in the chemokine receptor

    Authors: Liqing Wang, Qiuhong Xiong, Ping Li, Guangxin Chen, Nayab Tariq and Changxin Wu

    Citation: BMC Molecular and Cell Biology 2021 22:8

    Content type: Research article

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  16. One striking feature of the large KRAB domain-containing zinc finger protein (KZFP) family is its rapid evolution, leading to hundreds of member genes with various origination time in a certain mammalian genom...

    Authors: Pan Shen, Aishi Xu, Yushan Hou, Huqiang Wang, Chao Gao, Fuchu He and Dong Yang

    Citation: BMC Molecular and Cell Biology 2021 22:7

    Content type: Research article

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  17. Circular RNAs (circRNAs) are endogenous non-coding RNAs, which are associated with various biological processes, including microRNA (miRNA) interaction, protein binding and regulatory splicing. circRNA_0005529...

    Authors: Xing Zhang, Hongwei Yang, Yingdong Jia, Zhengwen Xu, Liuping Zhang, Meng Sun and Jing Fu

    Citation: BMC Molecular and Cell Biology 2021 22:6

    Content type: Research article

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  18. Most of the cells of the mammalian retina are terminally differentiated, and do not regenerate once fully developed. This implies that these cells have strict controls over their metabolic processes, including...

    Authors: Elisa A. Bonnin, Eugenio F. Fornasiero, Felix Lange, Christoph W. Turck and Silvio O. Rizzoli

    Citation: BMC Molecular and Cell Biology 2021 22:5

    Content type: Research article

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  19. Pathogenesis of Helicobacter Pylori (HP) vacuolating toxin A (vacA) depends on polymorphic diversity within the signal (s), middle (m), intermediate (i), deletion (d) and c-regions. These regions show distinct al...

    Authors: Djaleel Muhammad Soyfoo, Yussriya Hanaa Doomah, Dong Xu, Chao Zhang, Huai-Ming Sang, Yan-Yan Liu, Guo-Xin Zhang, Jian-Xia Jiang and Shun-Fu Xu

    Citation: BMC Molecular and Cell Biology 2021 22:4

    Content type: Research article

    Published on:

  20. Human ether-à-go-go-related gene potassium channel 1 (hERG) is a voltage-gated potassium channel, the voltage-sensing domain (VSD) of which is targeted by a gating-modifier toxin, APETx1. APETx1 is a 42-residue p...

    Authors: Kazuki Matsumura, Takushi Shimomura, Yoshihiro Kubo, Takayuki Oka, Naohiro Kobayashi, Shunsuke Imai, Naomi Yanase, Madoka Akimoto, Masahiro Fukuda, Mariko Yokogawa, Kazuyoshi Ikeda, Jun-ichi Kurita, Yoshifumi Nishimura, Ichio Shimada and Masanori Osawa

    Citation: BMC Molecular and Cell Biology 2021 22:3

    Content type: Research article

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  21. Breast cancer 2, early onset (BRCA2) is a tumor suppressor gene. The protein encoded by this gene plays an important role in homologous recombination (HR)-mediated DNA repair. Deleterious mutations in BRCA2 and d...

    Authors: Yasunaga Yoshikawa, Hajime Kozuma, Masami Morimatsu, Kaori Sugawara and Koichi Orino

    Citation: BMC Molecular and Cell Biology 2021 22:2

    Content type: Research article

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  22. Culturing primary epithelial cells has a major advantage over tumor-derived or immortalized cell lines as long as their functional phenotype and genetic makeup are mainly maintained. The swine model has shown ...

    Authors: Henry Bautista-Amorocho, Jorge Alexander Silva-Sayago, Diego A. Goyeneche-Patino, Tania Liseth Pérez-Cala, Fabio Macías-Gómez, Juan Carlos Arango-Viana and Alonso Martínez

    Citation: BMC Molecular and Cell Biology 2021 22:1

    Content type: Methodology article

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  23. In rice, the cortex and outer tissues play a key role in submergence tolerance. The cortex differentiates into aerenchyma, which are air-containing cavities that allow the flow of oxygen from shoots to roots, ...

    Authors: Thibault Mounier, Sergi Navarro-Sanz, Charlotte Bureau, Lefeuvre Antoine, Fabrice Varoquaux, Franz Durandet and Christophe Périn

    Citation: BMC Molecular and Cell Biology 2020 21:92

    Content type: Methodology article

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  24. The CD4 protein is an important surface marker of T lymphocytes, which can mediate the antigen presentation process by interacting with MHC II and TCR molecules in human and mouse.

    Authors: Weiya Zhang, Juan Ni, Jie Zhang, Lu Zhang, Huanhuan Zhou, Changzhi Zhao, Mengjin Zhu, Haiyan Wang, Jianlin Han, Xinyun Li and Shuhong Zhao

    Citation: BMC Molecular and Cell Biology 2020 21:91

    Content type: Research article

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  25. The zoonotic worm parasite Fasciola hepatica secretes an abundance of cathepsin L peptidases that are associated with virulence, invasiveness, feeding and migration. The peptidases are produced as inactive zymoge...

    Authors: Izanara C. Pritsch, Irina G. Tikhonova, Heather L. Jewhurst, Orla Drysdale, Krystyna Cwiklinski, Marcelo B. Molento, John P. Dalton and Carolina De M. Verissimo

    Citation: BMC Molecular and Cell Biology 2020 21:90

    Content type: Research article

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  26. Type A influenza viruses are contagious and even life-threatening if left untreated. So far, no broadly protective vaccine is available due to rapid antigenic changes and emergence of new subtypes of influenza...

    Authors: Davod Jafari, Sara Malih, Mohammad Mahmoudi Gomari, Marzieh Safari, Rasool Jafari and Mohammad Morad Farajollahi

    Citation: BMC Molecular and Cell Biology 2020 21:89

    Content type: Research article

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  27. Popeye domain-containing proteins 1 and 2 (POPDC1 and POPDC2) are transmembrane proteins involved in cyclic AMP-mediated signalling processes and are required for normal cardiac pacemaking and conduction. In o...

    Authors: Ian Holt, Heidi R. Fuller, Roland F. R. Schindler, Sally L. Shirran, Thomas Brand and Glenn E. Morris

    Citation: BMC Molecular and Cell Biology 2020 21:88

    Content type: Research article

    Published on:

  28. Caenorhabditis elegans is an excellent model organism for biological research, but its contributions to biochemical elucidation of eukaryotic transcription mechanisms have been limited. One of the biggest obstacl...

    Authors: Phillip Wibisono, Yiyong Liu and Jingru Sun

    Citation: BMC Molecular and Cell Biology 2020 21:87

    Content type: Methodology article

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  29. Like most major enzyme families, the M14 family of metallocarboxypeptidases (MCPs) contains a number of pseudoenzymes predicted to lack enzyme activity and with poorly characterized molecular function. The gen...

    Authors: R. Christian McDonald, Matthew J. Schott, Temitope A. Idowu and Peter J. Lyons

    Citation: BMC Molecular and Cell Biology 2020 21:86

    Content type: Research article

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  30. Liver sinusoidal endothelial cells (LSECs) and Kupffer cells (KCs; liver resident macrophages) form the body’s most effective scavenger cell system for the removal of harmful blood-borne substances, ranging fr...

    Authors: Sabin Bhandari, Ruomei Li, Jaione Simón-Santamaría, Peter McCourt, Steinar Daae Johansen, Bård Smedsrød, Inigo Martinez-Zubiaurre and Karen Kristine Sørensen

    Citation: BMC Molecular and Cell Biology 2020 21:85

    Content type: Research article

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  31. Maintenance of centrosome number in cells is essential for accurate distribution of chromosomes at mitosis and is dependent on both proper centrosome duplication during interphase and their accurate distributi...

    Authors: Alan-Michael Bresch, Nadiya Yerich, Rong Wang and Ann O. Sperry

    Citation: BMC Molecular and Cell Biology 2020 21:84

    Content type: Research article

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  32. The effects of diverse stresses ultimately alter the structures and functions of proteins. As molecular chaperones, heat shock proteins (HSPs) are a group of highly conserved proteins that help in the refoldin...

    Authors: Xin Zhang, Yuting Li, Yulong Sun, Mingxing Guo, Jianjun Feng, Yilei Wang and Ziping Zhang

    Citation: BMC Molecular and Cell Biology 2020 21:83

    Content type: Research article

    Published on:

  33. Pneumonia ranks as one of the main infectious sources of mortality among kids under 5 years of age, killing 2500 a day; late research has additionally demonstrated that mortality is higher in the elderly. A fe...

    Authors: Olalekan Olanrewaju Bakare, Marshall Keyster and Ashley Pretorius

    Citation: BMC Molecular and Cell Biology 2020 21:82

    Content type: Research article

    Published on:

  34. Although several studies demonstrate prion-like properties of Tau fibrils, the effect of size in the seeding capacity of these aggregates is not fully understood. The aim of this study is to characterize Tau s...

    Authors: André Marreiro, Kristof Van Kolen, Cristiano Sousa, Liesbet Temmerman, Bruno Vasconcelos, Rosa Crespo-Rodriguez, Jan R. T. van Weering, Debby Van Dam, Peter P. De Deyn, Adrian Apetri, Liliane Schoofs and Marc H. Mercken

    Citation: BMC Molecular and Cell Biology 2020 21:81

    Content type: Research article

    Published on:

  35. Arecoline is an alkaloid natural product found in the areca nut that can induce oral submucous fibrosis and subsequent development of cancer. However, numerous studies have shown that arecoline may inhibit fib...

    Authors: Qiang Chen, Jiuyang Jiao, Youyuan Wang, Zhihui Mai, Jing Ren, Sijie He, Xiaolan Li and Zheng Chen

    Citation: BMC Molecular and Cell Biology 2020 21:80

    Content type: Research article

    Published on:

  36. Non-professional phagocytosis is usually triggered by stimuli such as necrotic cell death. In tumor therapy, the tumors often disappear slowly and only long time after the end of therapy. Here, tumor therapy i...

    Authors: Dorian Gottwald, Florian Putz, Nora Hohmann, Maike Büttner-Herold, Markus Hecht, Rainer Fietkau and Luitpold Distel

    Citation: BMC Molecular and Cell Biology 2020 21:79

    Content type: Research article

    Published on:

  38. Local Chinese local pig breeds have thinner muscle fiber and higher intramuscular-fat (IMF) content. But its regulation mechanism has not been discussed in-depth. Studies indicated that long non coding RNAs (l...

    Authors: Jing Wang, Ming-yue Chen, Jun-feng Chen, Qiao-ling Ren, Jia-qing Zhang, Hai Cao, Bao-song Xing and Chuan-ying Pan

    Citation: BMC Molecular and Cell Biology 2020 21:77

    Content type: Research article

    Published on:

  39. MreB is a bacterial ortholog of actin and forms mobile filaments underneath the cell membrane, perpendicular to the long axis of the cell, which play a crucial role for cell shape maintenance. We wished to vis...

    Authors: Simon Dersch, Christian Reimold, Joshua Stoll, Hannes Breddermann, Thomas Heimerl, Hervé Joel Defeu Soufo and Peter L. Graumann

    Citation: BMC Molecular and Cell Biology 2020 21:76

    Content type: Research article

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  40. Many cell permeabilisation methods to mediate internalisation of various molecules to mammalian or bacterial cells have been developed. However, no size-specific permeability assay suitable for both cell types...

    Authors: Yensi Flores Bueso, Sidney Walker, Jennifer Quinn and Mark Tangney

    Citation: BMC Molecular and Cell Biology 2020 21:75

    Content type: Methodology article

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  41. The clinical efficacy of specific interleukin-6 inhibitors has confirmed the central role of IL6 in rheumatoid arthritis (RA). However the local role of IL6, in particular in synovial fibroblasts (SF) as a dir...

    Authors: Alvaro Valin, Manuel J. Del Rey, Cristina Municio, Alicia Usategui, Marina Romero, Jesús Fernández-Felipe, Juan D. Cañete, Francisco J. Blanco, Yolanda Ruano, Gabriel Criado and José L. Pablos

    Citation: BMC Molecular and Cell Biology 2020 21:74

    Content type: Research article

    Published on:

  42. Persistence is a natural phenomenon whereby a subset of a population of isogenic bacteria either grow slow or become dormant conferring them with the ability to withstand various stresses including antibiotics...

    Authors: Cyrus Alexander, Ankeeta Guru, Pinkilata Pradhan, Sunanda Mallick, Nimai Charan Mahanandia, Bharat Bhusan Subudhi and Tushar Kant Beuria

    Citation: BMC Molecular and Cell Biology 2020 21:73

    Content type: Research article

    Published on:

  43. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Ye Zhao, Xi Qiao, Lihua Wang, Tian Kui Tan, Hong Zhao, Yun Zhang, Jianlin Zhang, Padmashree Rao, Qi Cao, Yiping Wang, Ya Wang, Yuan Min Wang, Vincent W. S. Lee, Stephen I. Alexander, David C. H. Harris and Guoping Zheng

    Citation: BMC Molecular and Cell Biology 2020 21:72

    Content type: Correction

    Published on:

    The original article was published in BMC Cell Biology 2016 17:21

  44. The Werner syndrome protein (WRN) belongs to the RecQ family of helicases and its loss of function results in the premature aging disease Werner syndrome (WS). We previously demonstrated that an early cellular...

    Authors: Juan Manuel Iglesias-Pedraz, Diego Matia Fossatti-Jara, Valeria Valle-Riestra-Felice, Sergio Rafael Cruz-Visalaya, Jose Antonio Ayala Felix and Lucio Comai

    Citation: BMC Molecular and Cell Biology 2020 21:71

    Content type: Research article

    Published on:

  45. Microautophagy, which degrades cargos by direct lysosomal/vacuolar engulfment of cytoplasmic cargos, is promoted after nutrient starvation and the inactivation of target of rapamycin complex 1 (TORC1) protein ...

    Authors: Shamsul Morshed, Most Naoshia Tasnin and Takashi Ushimaru

    Citation: BMC Molecular and Cell Biology 2020 21:70

    Content type: Research article

    Published on:

  46. Long non-coding RNAs (lncRNAs) are novel regulatory molecules in breast cancer development. LncRNA LUCAT1 is a potential tumor promoter in human cancers. In this study, we aimed to explore the role of LUCAT1 i...

    Authors: Yun Liu, Teng Cheng, Yaying Du, Xiaopeng Hu and Wenfei Xia

    Citation: BMC Molecular and Cell Biology 2020 21:69

    Content type: Research article

    Published on:

  47. MCF-7 breast cancer cell line is undoubtedly amongst the most extensively studied patient-derived research models, providing pivotal results that have over the decades translated to constantly improving patien...

    Authors: Nityanand Jain, Dina Nitisa, Valdis Pirsko and Inese Cakstina

    Citation: BMC Molecular and Cell Biology 2020 21:68

    Content type: Research article

    Published on:

  48. G-quadruplexes regulate gene expression, recombination, packaging and latency in herpesviruses. Herpesvirus-encoded miRNAs have been linked to important biological functions. The presence and the biological ro...

    Authors: Shivani Kumar, Divya Choudhary, Anupam Patra, Neel Sarovar Bhavesh and Perumal Vivekanandan

    Citation: BMC Molecular and Cell Biology 2020 21:67

    Content type: Research article

    Published on:

  49. The increasing incidence of reproductive disorders in humans has been attributed to in utero exposure to estrogenic endocrine disruptors. In particular, exposure of the developing testis to exogenous estrogen ...

    Authors: Melanie K. Stewart, Deidre M. Mattiske and Andrew J. Pask

    Citation: BMC Molecular and Cell Biology 2020 21:66

    Content type: Research article

    Published on:

  50. The human Obg-like ATPase 1 (OLA1) protein has been reported to play an important role in cancer cell proliferation. The molecular mechanism underlying OLA1 regulated oral metastasis is still unknown. We inves...

    Authors: Jianzhou Liu, Qing Yang, Kevin Chen Xiao, Thomas Dobleman, Shen Hu and Gary Guishan Xiao

    Citation: BMC Molecular and Cell Biology 2020 21:65

    Content type: Research article

    Published on:

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