Skip to main content

Articles

Page 1 of 23

  1. Hepatocellular carcinoma (HCC) is a common malignancy. Long non-coding RNAs (lncRNAs) partake in the progression of HCC. However, the role of lncRNA MAPKAPK5-AS1 in the development of HCC has not been fully cl...

    Authors: Zongqing Peng, Xinhua Ouyang, Yexing Wang and Qiming Fan
    Citation: BMC Molecular and Cell Biology 2022 23:21
  2. This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/1471-2091-13-25.

    Authors: Yuejin Li, Na Liu, Damao Huang, Zhenlin Zhang, Zhengke Peng, Chaojun Duan, Xiaowei Tang, Gongjun Tan, Guangrong Yan, Wenhua Mei and Faqing Tang
    Citation: BMC Molecular and Cell Biology 2022 23:20
  3. Triple-negative breast cancer (TNBC) is the most severe type of breast cancer owing to its high heterogeneity, aggressiveness and lack of treatment. Studies have reported that uncarboxylated osteocalcin (GluOC...

    Authors: Jiaojiao Xu, Luyao Ma, Danqing Wang and Jianhong Yang
    Citation: BMC Molecular and Cell Biology 2022 23:18
  4. We have previously found that, in the pathogenic yeast Candida albicans, 18S and 25S ribosomal RNA components, containing more than one phosphate on their 5′-end were resistant to 5′-monophosphate requiring 5′ → ...

    Authors: Miguel A. Rocha, Bhavani S. Gowda and Jacob Fleischmann
    Citation: BMC Molecular and Cell Biology 2022 23:17
  5. Besides controlling the expression of peripheral tissue antigens, the autoimmune regulator (AIRE) gene also regulates the expression of adhesion genes in medullary thymic epithelial cells (mTECs), an essential pr...

    Authors: Ana Carolina Monteleone-Cassiano, Janaina A. Dernowsek, Romario S. Mascarenhas, Amanda Freire Assis, Dimitrius Pitol, Natalia Chermont Santos Moreira, Elza Tiemi Sakamoto-Hojo, João Paulo Mardegan Issa, Eduardo A. Donadi and Geraldo Aleixo Passos
    Citation: BMC Molecular and Cell Biology 2022 23:15
  6. The nucleolus is a subnuclear, non-membrane bound domain that is the hub of ribosome biogenesis and a critical regulator of cell homeostasis. Rapid growth and division of cells in tumors are correlated with in...

    Authors: Marzia Tagliaferro, Paolo Rosa, Gian Carlo Bellenchi, Daniela Bastianelli, Rosa Trotta, Claudia Tito, Francesco Fazi, Antonella Calogero and Donatella Ponti
    Citation: BMC Molecular and Cell Biology 2022 23:13
  7. The epidermal growth factor receptor (EGFR) is involved in various developmental processes, and alterations of its extracellular segment are associated with several types of cancers, in particular glioblastoma...

    Authors: Matthieu R. Zeronian, Sofia Doulkeridou, Paul M. P. van Bergen en Henegouwen and Bert J. C. Janssen
    Citation: BMC Molecular and Cell Biology 2022 23:12
  8. To circumvent some pitfalls related to acute status, chronic model of asthma is conceived to be more suitable approach to guarantee the conditions which are similar to human pulmonary disease. Here, possible t...

    Authors: Sajjad Taghizadeh, Rana Keyhanmanesh, Reza Rahbarghazi, Jafar Rezaie, Aref Delkhosh, Mehdi Hassanpour, Hossein Heiran, Arshad Ghaffari-Nasab and Mahdi Ahmadi
    Citation: BMC Molecular and Cell Biology 2022 23:11
  9. Swi6 acts as a transcription factor in budding yeast, functioning in two different heterodimeric complexes, SBF and MBF, that activate the expression of distinct but overlapping sets of genes. Swi6 undergoes r...

    Authors: Kenneth D. Belanger, William T. Yewdell, Matthew F. Barber, Amy N. Russo, Mark A. Pettit, Emily K. Damuth, Naveen Hussain, Susan J. Geier and Karyn G. Belanger
    Citation: BMC Molecular and Cell Biology 2022 23:10
  10. Image segmentation is considered an important step in image processing. Fuzzy c-means clustering is one of the common methods of image segmentation. However, this method suffers from drawbacks, such as sensiti...

    Authors: Maryam Mohammdian-khoshnoud, Ali Reza Soltanian, Arash Dehghan and Maryam Farhadian
    Citation: BMC Molecular and Cell Biology 2022 23:9
  11. Protein-protein interactions form the basis of every organism and thus, investigating their dynamics, intracellular protein localization, trafficking and interactions of distinct proteins such as receptors and...

    Authors: Victoria Elisabeth Groß, Miron Mikhailowitsch Gershkovich, Torsten Schöneberg, Anette Kaiser and Simone Prömel
    Citation: BMC Molecular and Cell Biology 2022 23:8
  12. Authors: Shannon Robin, Khalil Ben Hassine, Jayaraman Muthukumaran, Simona Jurkovic Mlakar, Maja Krajinovic, Tiago Nava, Chakradhara Rao S. Uppugunduri and Marc Ansari
    Citation: BMC Molecular and Cell Biology 2022 23:6

    The original article was published in BMC Molecular and Cell Biology 2022 23:5

  13. Sinusoidal occlusion syndrome (SOS) is a potentially severe complication following hematopoietic stem cell transplantation (HSCT) in pediatric patients. Treatment related risk factors such as intensity of cond...

    Authors: Shannon Robin, Khalil Ben Hassine, Jayaraman Muthukumaran, Simona Jurkovic Mlakar, Maja Krajinovic, Tiago Nava, Chakradhara Rao S. Uppugunduri and Marc Ansari
    Citation: BMC Molecular and Cell Biology 2022 23:5

    The Correction to this article has been published in BMC Molecular and Cell Biology 2022 23:6

  14. T-2 toxin is thought to induce the growth plate and articular cartilage damage of Kashin-Beck disease (KBD), an endemic osteochondropathy in China. This study aims to explore the potential underlying mechanism...

    Authors: Xuena Yang, Xue Xiao, Lu Zhang, Bo Wang, Ping Li, Bolun Cheng, Chujun Liang, Mei Ma, Xiong Guo, Feng Zhang and Yan Wen
    Citation: BMC Molecular and Cell Biology 2022 23:4
  15. Organogenesis from tonsil-derived mesenchymal cells (TMSCs) has been reported, wherein tenogenic markers are expressed depending on the chemical stimulation during tenogenesis. However, there are insufficient ...

    Authors: Jaeyeon Wee, Hyang Kim, Sang-Jin Shin, Taeyong Lee and Seung Yeol Lee
    Citation: BMC Molecular and Cell Biology 2022 23:3

    The Correction to this article has been published in BMC Molecular and Cell Biology 2022 23:7

  16. SARS-CoV-2, the causative agent of COVID-19 pandemic is a RNA virus prone to mutations. Formation of a stable binding interface between the Receptor Binding Domain (RBD) of SARS-CoV-2 Spike (S) protein and Ang...

    Authors: Shijulal Nelson-Sathi, P. K. Umasankar, E. Sreekumar, R. Radhakrishnan Nair, Iype Joseph, Sai Ravi Chandra Nori, Jamiema Sara Philip, Roshny Prasad, K. V. Navyasree, Shikha Ramesh, Heera Pillai, Sanu Ghosh, T. R. Santosh Kumar and M. Radhakrishna Pillai
    Citation: BMC Molecular and Cell Biology 2022 23:2
  17. Uncontrolled growth in solid breast cancer generates mechanical compression that may drive the cancer cells into a more invasive phenotype, but little is known about how such compression affects the key events...

    Authors: Mingzhi Luo, Grace Cai, Kenneth K. Y. Ho, Kang Wen, Zhaowen Tong, Linhong Deng and Allen P. Liu
    Citation: BMC Molecular and Cell Biology 2022 23:1
  18. Thymidine kinase 1 (TK1) plays a key role in the synthesis of deoxythymidine triphosphate (dTTP) and is thus important for DNA replication and cell proliferation. The expression of TK1 is highest during S-phas...

    Authors: Liya Wang, Lucia Unger, Hanan Sharif, Staffan Eriksson, Vinzenz Gerber and Henrik Rönnberg
    Citation: BMC Molecular and Cell Biology 2021 22:59
  19. Producing an appropriate number of engineered cells is considered as one of the influential factors in the successful treatments with chimeric antigen receptor (CAR) T cells. To this aim, the transduction rate...

    Authors: Alireza Rajabzadeh, Amir Ali Hamidieh and Fatemeh Rahbarizadeh
    Citation: BMC Molecular and Cell Biology 2021 22:57
  20. Abnormal proliferation and migration of human airway smooth muscle cells (HASMCs) play an important role in the development of childhood asthma. Long non-coding RNAs (lncRNAs) have been demonstrated to partici...

    Authors: Xinfang Wang and Junsong Chen
    Citation: BMC Molecular and Cell Biology 2021 22:56
  21. Psoriasis is a chronic inflammatory disease dependent upon a complex interaction between genetic predisposition and immunological factors. It is characterized by skin lesions throughout the body, causing great...

    Authors: Mariana Fatima Muaccad Gama Wagner, Thérèse Rachell Theodoro, Carlos D’. Apparecida Santos Machado Filho, Luiza Keiko Matsuka Oyafuso and Maria Aparecida Silva Pinhal
    Citation: BMC Molecular and Cell Biology 2021 22:55
  22. Organic anion transporter 1 (OAT1) is a drug transporter expressed on the basolateral membrane of the proximal tubule cells in kidneys. It plays an essential role in the disposition of numerous clinical therap...

    Authors: Zhou Yu, Chenchang Liu, Jinghui Zhang, Zhengxuan Liang and Guofeng You
    Citation: BMC Molecular and Cell Biology 2021 22:53
  23. RhoA is a master regulator of cytoskeletal contractility, while nitric oxide (NO) is a master regulator of relaxation, e.g., vasodilation. There are multiple forms of cross-talk between the RhoA/ROCK pathway a...

    Authors: Akila Surendran, C. Forbes Dewey Jr, Boon Chuan Low and Lisa Tucker-Kellogg
    Citation: BMC Molecular and Cell Biology 2021 22(Suppl 1):47

    This article is part of a Supplement: Volume 22 Supplement 1

  24. Mitochondrial DNA (mtDNA) carrying certain pathogenic mutations or single nucleotide variants (SNVs) enhances the invasion and metastasis of tumor cells, and some of these mutations are homoplasmic in tumor ce...

    Authors: Keizo Takenaga, Nobuko Koshikawa and Hiroki Nagase
    Citation: BMC Molecular and Cell Biology 2021 22:52
  25. Apoptosis is a caspase regulated cell death present in all metazoans defined by a conserved set of morphological features. A well-described function of apoptosis is the removal of excessive cells during develo...

    Authors: Gabriel Krasovec, Anthi Karaiskou, Éric Quéinnec and Jean-Philippe Chambon
    Citation: BMC Molecular and Cell Biology 2021 22:51
  26. Cryopreservation of human spermatozoa has been identified as an efficient procedure to preserve fertility in men before any cancer therapy or surgical infertility treatment. Despite the benefits of the procedu...

    Authors: Fatemeh Eini, Maryam Azizi kutenaei, Maryam Hosseinzadeh Shirzeyli, Zeinolabedin Sharifian Dastjerdi, Mahmoud Omidi and Marefat Ghaffari Novin
    Citation: BMC Molecular and Cell Biology 2021 22:50
  27. The seriousness and menace of the worldwide weight of ‘Alzheimer’s disease have been related to a few factors, which incorporate antioxidant system depletion, mutation of proteins, and high expression of choli...

    Authors: Olalekan Olanrewaju Bakare, Adewale Oluwaseun Fadaka, Musa Oyebowale Akanbi, Kolajo Adedamola Akinyede, Ashwil Klein and Marshall Keyster
    Citation: BMC Molecular and Cell Biology 2021 22:49
  28. Cisd1 and Cisd2 proteins share very similar structures with an N-terminal membrane-anchoring domain and a C-terminal cytosolic domain containing an iron-cluster binding domain and ending with a C-terminal KKxx...

    Authors: Claudie Bian, Anna Marchetti, Philippe Hammel and Pierre Cosson
    Citation: BMC Molecular and Cell Biology 2021 22:48
  29. MDM2 is an E3 ubiquitin ligase that is able to ubiquitinate p53, targeting it for proteasomal degradation. Its homologue MDMX does not have innate E3 activity, but is able to dimerize with MDM2. Although mouse...

    Authors: Jack D. Sanford, Jing Yang, Jing Han, Laura A. Tollini, Aiwen Jin and Yanping Zhang
    Citation: BMC Molecular and Cell Biology 2021 22:46
  30. The crucial role of the major histocompatibility complex (MHC) for the immune response to infectious diseases is well-known, but no information is available on the 3D nuclear organization of this gene-dense re...

    Authors: Florence Mompart, Alain Kamgoué, Yvette Lahbib-Mansais, David Robelin, Agnès Bonnet, Claire Rogel-Gaillard, Silvia Kocanova and Martine Yerle-Bouissou
    Citation: BMC Molecular and Cell Biology 2021 22:45
  31. Sequence-specific transcription factors (TFs) recognize motifs of related nucleotide sequences at their DNA binding sites. Upon binding at these sites, TFs regulate critical molecular processes such as gene ex...

    Authors: Luis Chumpitaz-Diaz, Md. Abul Hassan Samee and Katherine S. Pollard
    Citation: BMC Molecular and Cell Biology 2021 22:44
  32. The 7SK small nuclear RNA (snRNA) found in most metazoans is a key regulator of P-TEFb which in turn regulates RNA polymerase II elongation. Although its primary sequence varies in protostomes, its secondary s...

    Authors: Duy Nguyen, Nicolas Buisine, Olivier Fayol, Annemieke A. Michels, Olivier Bensaude, David H. Price and Patricia Uguen
    Citation: BMC Molecular and Cell Biology 2021 22:43
  33. Although bacterial infections have been recognized as a possible cause of male infertility, the effect of bacterial infections on sperm quality and sperm DNA fragmentation remains controversial. The current st...

    Authors: Fatemeh Eini, Maryam Azizi Kutenaei, Fayegheh Zareei, Zeinolabedin Sharifian Dastjerdi, Maryam Hosseinzadeh Shirzeyli and Ensieh Salehi
    Citation: BMC Molecular and Cell Biology 2021 22:42
  34. The human SH3 domain Binding Glutamic acid Rich Like 3 (SH3BGRL3) gene is highly conserved in phylogeny and widely expressed in human tissues. However, its function is largely undetermined. The protein was found ...

    Authors: Filippo Di Pisa, Elisa Pesenti, Maria Bono, Andrea N. Mazzarello, Cinzia Bernardi, Michael P. Lisanti, Giovanni Renzone, Andrea Scaloni, Ermanno Ciccone, Franco Fais, Silvia Bruno, Paolo Scartezzini and Fabio Ghiotto
    Citation: BMC Molecular and Cell Biology 2021 22:41
  35. In retinal degenerative disease, progressive and debilitating conditions result in deterioration of retinal cells and visual loss. In human, retina lacks the inherent capacity for regeneration. Therefore, rege...

    Authors: Atefeh Atefi, Pendar Shojaei Kojouri, Fereshteh Karamali, Shiva Irani and Mohammad Hossein Nasr-Esfahani
    Citation: BMC Molecular and Cell Biology 2021 22:40
  36. Research on cell-in-cell (CIC) phenomena, including entosis, emperipolesis and cannibalism, and their biological implications has increased in recent years. Homotypic and heterotypic engulfment of various targ...

    Authors: Mareike F. Bauer, Michael Hader, Markus Hecht, Maike Büttner-Herold, Rainer Fietkau and Luitpold V. R. Distel
    Citation: BMC Molecular and Cell Biology 2021 22:39
  37. Proper muscle function is heavily dependent on highly ordered protein complexes. UNC45 is a USC (named since this region is shared by three proteins UNC45/CRO1/She4P) chaperone that is necessary for myosin inc...

    Authors: Abiramy Karunendiran, Christine T. Nguyen, Virginijus Barzda and Bryan A. Stewart
    Citation: BMC Molecular and Cell Biology 2021 22:38
  38. Organ culture models have been used over the past few decades to study development and disease. The in vitro three-dimensional (3D) culture system of organoids is well known, however, these 3D systems are both...

    Authors: Soran Dakhel, Wayne I. L. Davies, Justin V. Joseph, Tushar Tomar, Silvia Remeseiro and Lena Gunhaga
    Citation: BMC Molecular and Cell Biology 2021 22:37
  39. Climate change and the associated risk for the occurrence of extreme temperature events or permanent changes in ambient temperature are important in the husbandry of farm animals. The aim of our study was to i...

    Authors: Katharina Metzger, Dirk Dannenberger, Armin Tuchscherer, Siriluck Ponsuksili and Claudia Kalbe
    Citation: BMC Molecular and Cell Biology 2021 22:36
  40. Succinate dehydrogenase (Complex II) plays a dual role in respiration by catalyzing the oxidation of succinate to fumarate in the mitochondrial Krebs cycle and transferring electrons from succinate to ubiquino...

    Authors: Aloka B. Bandara, Joshua C. Drake and David A. Brown
    Citation: BMC Molecular and Cell Biology 2021 22:35
  41. Epidermal growth factor receptor (EGFR) and its signaling pathways play a vital role in pathogenesis of lung cancer. By disturbing EGFR signaling, mutations of EGFR may lead to progression of cancer or the eme...

    Authors: Mengxu Zhu, Debby D. Wang and Hong Yan
    Citation: BMC Molecular and Cell Biology 2021 22:34
  42. In the present study, fatty acid synthesis is targeted to combat mammary gland carcinoma by activating prolyl hydroxylase-2 with Voacamine alone and in combination with Tamoxifen. It was hypothesized that the ...

    Authors: Lakhveer Singh, Manjari Singh, Shubham Rastogi, Anurag Choudhary, Dinesh Kumar, Ritu Raj, Mohd Nazam Ansari, Abdulaziz S. Saeedan and Gaurav Kaithwas
    Citation: BMC Molecular and Cell Biology 2021 22:33
  43. Endothelial healing after deployment of cardiovascular devices is particularly important in the context of clinical outcome. It is therefore of great interest to develop tools for a precise prediction of endot...

    Authors: Jan Oldenburg, Lisa Maletzki, Anne Strohbach, Paul Bellé, Stefan Siewert, Raila Busch, Stephan B. Felix, Klaus-Peter Schmitz and Michael Stiehm
    Citation: BMC Molecular and Cell Biology 2021 22:32

Annual Journal Metrics