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Table 1 Co-localization of SMN with p53 in fibroblasts

From: Increased susceptibility of spinal muscular atrophy fibroblasts to camptothecin is p53-independent

  Type I Type II Type III Control
Untreated     
Gem number/100 cells 6 16 24 114
Average gem size ± SD (nm) 538 ± 37 603 ± 73 649 ± 121 715 ± 153
% of co-localization with p53 83.3 75.0 75.0 99.1
CPT treated     
Gem number/100 cells 6 11 17 80
Average gem size ± SD (nm) 544 ± 22 542 ± 53 689 ± 154 793 ± 173
% of co-localization with p53 100.0 63.0 64.7 85.0