Table 1 Co-localization of SMN with p53 in fibroblasts
From: Increased susceptibility of spinal muscular atrophy fibroblasts to camptothecin is p53-independent
Type I | Type II | Type III | Control | |
|---|---|---|---|---|
Untreated | ||||
Gem number/100 cells | 6 | 16 | 24 | 114 |
Average gem size ± SD (nm) | 538 ± 37 | 603 ± 73 | 649 ± 121 | 715 ± 153 |
% of co-localization with p53 | 83.3 | 75.0 | 75.0 | 99.1 |
CPT treated | ||||
Gem number/100 cells | 6 | 11 | 17 | 80 |
Average gem size ± SD (nm) | 544 ± 22 | 542 ± 53 | 689 ± 154 | 793 ± 173 |
% of co-localization with p53 | 100.0 | 63.0 | 64.7 | 85.0 |