Table 1 Accumulated insulin, C-peptide and pro-insulin release and insulin content.
From: Generation and characterization of human insulin-releasing cell lines
VGA | APM | CPR | hBeta-cells | |
|---|---|---|---|---|
Insulin release (ng/ngDNA) | 5 × 10-2 ± 1 × 10-2 | 2.5 × 10-2 ± 3 × 10-3 | 9 × 10-3 ± 1 × 10-3 | 9 × 10-5 ± 1 × 10-5 |
Insulin content (ng/ng DNA) | <3 × 10-7 | <3 × 10-7 | <3 × 10-7 | 3 × 10-4 ± 1 × 10-4 |
Pro-Insulin release (pmol/ng DNA) | 8 × 10-4 ± 2 × 10-4 | 3 × 10-4 ± 3 × 10-5 | 3 × 10-4 ± 1 × 10-5 | N.D. |
C-peptide release (ng/ng DNA) | 5 × 10-2 ± 1 × 10-2 | 5 × 10-2 ± 1 × 10-2 | 5 × 10-2 ± 1 × 10-2 | 5 × 10-2 ± 1 × 10-2 |
Glucose-induced insulin secretion (Stimulation Index)a | 1 | 1 | 1 | >3 |