Figure 4
From: Ethanol exerts dual effects on calcium homeostasis in CCK-8-stimulated mouse pancreatic acinar cells
![Figure 4](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2F1471-2121-10-77/MediaObjects/12860_2009_Article_426_Fig4_HTML.jpg)
Changes in [Ca2+] i in response to CCK-8 and effect of ethanol. Time-course of changes in [Ca2+]i in fura-2-loaded mouse pancreatic acinar cells. Cells were stimulated with 1 nM CCK-8 alone (full circles) or in the presence of 50 mM ethanol (EtOH; open circles) in the presence of Ca2+ in the extracellular medium. The arrow indicates the time point at which CCK-8 was added to the cells. In the experiments in which its effect was assayed, EtOH was added to the cells 1 minute prior to addition of CCK-8. The traces are typical of 14-17 such independent experiments.