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Table 1 Biochemical Binding Parameters from Solid Phase Assays

From: The proline-rich domain of tau plays a role in interactions with actin

actin Bmax (μM) Kapp (μM) R
α-G- 2.10 ± 0.07 0.031 ± 0.007 0.99
α-F- 2.31 ± 0.05 0.030 ± 0.004 0.99
β/γ-G- 1.90 ± 0.06 0.029 ± 0.005 0.99
β/γ-F- 2.01 ± 0.04 0.027 ± 0.003 0.99
  1. Conditions were the same as those referred to in Figure 1. Binding parameters were estimated with the non-linear curve fit Hyperbl function (ΔA450 = Bmax * [tau]/(Kapp+ [tau]) in the Origin program.