Figure 1
![Figure 1](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2F1471-2121-10-85/MediaObjects/12860_2009_Article_434_Fig1_HTML.jpg)
Occludin and occludin disrupting molecules. The general topology of the tetraspanin molecule occludin and the FLAG tagged truncated fragment used to make the truncated molecule, F-ΔOcc, are shown in diagrammatic format along with the location of an occludin disrupting peptide. COOH, C-terminus; PM, plasma membrane; F, FLAG epitope tag; rs, restriction site used to make truncated occludin; LYHY, conserved peptide sequence used in later experiments.