Table 1 Summary of nuclear-localized RTKs by PSORT II prediction
| Â | PSORT II results (NNCN score) | References |
|---|---|---|
EGFR family: EGFR | Nuclear (70.6) | Dittmann et al., 2005 [46]; Dittmann et al., 2008 [47]; Hoshino et al., 2007 [48]; Hsu and Hung, 2007 [4]; Hu et al., 2007 [49]; Hung et al., 2008 [5]; Lo et al., 2006a [50]; Lo et al., 2005 [23]; Lo et al., 2006b [51]; Lo and Hung, 2007 [52] |
ERBB-2 | Cytoplasmic (55.5) | Xie and Hung, 1994 [6]; Giri et al., 2005 [7]; Wang et al., 2004 [53] |
ERBB-3 | Nuclear (70.6) | Cheng et al., 2007 [8] |
ERBB-4 | Nuclear (55.5) | Feng et al., 2009 [11]; Ni et al., 2003 [9]; Sundvall et al., 2007 [54]; Williams et al., 2004 [10] |
FGFR family: FGFR1 | Nuclear (55.5) | Kilkenny and Hill, 1996 [12]; Myers et al., 2003 [14]; Peng et al., 2002 [13]; Stachowiak et al., 1996 [55] |
FGFR3 | Cytoplasmic (89) | Johnston et al., 1995 [15] |
ROR family: ROR1 | Nuclear (89) | None reported |
ROR2 | Nuclear (70.6) | None reported |
VEGFR family: VEGFR1 | Nuclear (70.6) | None reported |
VEGFR2 | Cytoplasmic (76.7) | |
AATYK family: LMTK2 | Nuclear (89) | None reported |
TRK family: NTRK1 | Cytoplasmic (94.1) | Bonacchi et al., 2008 [17]; Gong et al., 2007 [56]; Lee et al., 1998 [16] |