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Figure 1 | BMC Cell Biology

Figure 1

From: Hydrogen peroxide stimulates nuclear import of the POU homeodomain protein Oct-1 and its repressive effect on the expression of Cdx-2

Figure 1

H 2 O 2 enhances nuclear Oct-1 content. (A) InR1-G9 cells were treated with the indicated amount of H2O2 for 2 or 4 h. Oct-1 expression in whole cell lysates (WCL), nuclear extract (NE), and cytosol were then assessed. (B, C) Effect of H2O2 on Oct-1 nuclear translocation in intestinal GLUTag and pancreatic Ins-1 cell lines, two non-endocrine cell lines (Cos-7 and Caco-2) (B) and the primary rat smooth muscle cells (C).

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