Figure 4From: LKB1 tumor suppressor protein regulates actin filament assembly through Rho and its exchange factor Dbl independently of kinase activityDominant negative RhoA inhibits stress fiber formation. A-C. Cells were co-transfected with GFP-DN-Cdc42 (N17Cdc42) and pRK5-myc-LKB1 constructs. D-F. Cells were co-transfected with GFP-DN-RhoA (N19RhoA) and pRK5-myc-LKB1. Cells expressing both GFP and myc were counted and scored for stress fiber formation. Scale bar = 20 μm.Back to article page