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Figure 5 | BMC Cell Biology

Figure 5

From: GDNF stimulates the proliferation of cultured mouse immature Sertoli cells via its receptor subunit NCAM and ERK1/2 signaling pathway

Figure 5

Proliferation enhancement effects of GDNF on cultured ISCs is completely abolished by the ERK1/2 inhibitor PD98059. (A-D) BrdU-positive cells in control (A), PD98059 treated (B), GDNF stimulated (C) and pre-treated with PD98059 plus GDNF stimulation groups (D). (E) Quantitative analysis results. The data were presented as means ± SD from three independent experiments. Statistically significant differences (p < 0.05) among groups are indicated by an asterisk. Scale bar indicates 10 μm.

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