Figure 3From: Erythropoietin and the effect of oxygen during proliferation and differentiation of human neural progenitor cellsProliferation of hNPCs. Effects of high and low oxygen concentration on the proliferation of hNPCs. Cells were treated with different EPO concentrations up to 4 d. Number of cells/ml was determined at 20% oxygen (A) and 3% oxygen (B). Comparing untreated cells (C), hypoxia had no impact on the proliferation rate within 4 d. The doubling times are not different between both oxygen concentrations and EPO did not influence the proliferation of cells at different concentrations (E). As control for a positive EPO-response, HCD-57 cells were used (D). Data are presented as mean ± SEM, n = 3-11 in triplicates.Back to article page