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Table 1 Summary of the cytostatic activities of mutant TC14-3s.

From: Tunicate cytostatic factor TC14-3 induces a polycomb group gene and histone modification through Ca2+ binding and protein dimerization

F65D T69R G70R A103S G105D E106G N109G A111Q G112S K113S N114E K113SN114E N136R T144D K145D
- - +++ +++ +++ - ++ +++ +++ ++ ++ + +++ +++ +++
  1. +++, Cytostatic activities remained strong.
  2. ++, Cytostatic activities faintly decreased.
  3. +, Cytostatic activities were weakened to a large extent.
  4. -, Cytostatic activities were almost lost.