Cardiac structure and function in pressure-overloaded rat hearts. Blood pressure in the control group and the pressure-overloaded group (A), (B); systolic blood pressure (A) and diastolic blood pressure (B), pre: n=11, 2w: control n=6, banding n=4, 4w: control n=4, banding n=5. LV mass (C), heart/body weight ratio (D) and mean diameters of left ventricular cardiac myocytes (E) in the control group and the pressure-overloaded group, 2w: control n=11, banding n=9, 4w: control n=7, banding n=8. Echocardiographic evaluation of left ventricular function (F), (G). Ejection fraction (F) and the transmitral E/A ratio (G), pre: n=13, 2w: control n=5, banding n=7, 4w: control n=5, banding n=5. Values are reported as means ± SD. *p<0.05, **p<0.01 vs. control.