Figure 3

TAGLN enhances tumor metastasis through human tumor xenograft model in vivo. A: nude mice metastatic nodules in the lung. a1: lung metastatic nodules from tomur-bearing mouse. Arrow: metastatic nodule. a2: no metastatic nodule in lung. a3: H&E staining for lung metastatic nodule under bright-field microscope. Scale bars, 200 μm. a4: H&E staining for lung without metastatic nodule under bright-field microscope. Scale bars, 200 μm. B: quantification of nude mice lung metastatic nodules in various groups through tail intravenous injection. *, P < 0.05, by one-way analysis of variance (ANOVA).