Figure 7
From: Claudins play a role in normal and tumor cell motility
Wound healing response to peptide is specific for collagen. Normal human mammary epithelial (16N) as well as breast (T47D) and ovarian (OVCAR3) tumor cell monolayers, grown on 30 µg/ml fibronectin-coated glass chamber slides, were scratched and the size of the gap remaining at 4 (16N) or 24 (T47D, OVCAR3) hours was measured using SlideBook software. The size of the gap was compared between non-treated cells (white bars) and cells treated with 400 µM mimic peptide. Mean ± s.e.m., n=4 wells for each treatment (20 measurements taken for each well) *p < 0.05 vs. non-treated.