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Table 1 Development of diabetes in ZDF (zucker fatty rat) was monitored by measurement of HbA1c, glucose and body weight

From: Increased protein aggregation in Zucker Diabetic Fatty rat brain: identification of key mechanistic targets and the therapeutic application of hydrogen sulfide

 

Wk 7

Wk 9

Wk 11

Wk 13

Wk 15

Wk 17

Glucose (mmol/l)

      

Lean

7.8±0.4

8.9±0.1

8.3±0.2

8.3±0.2

8.5±0.3

8.3±0.2

ZDF

9.2±1.4*

9.9±0.6*

9.2±0.4*

9.6±0.4*

10.6±1.0*

11.0±1.0*

HbA1c (%)

      

Lean

2.9±0.01

   

3.4±0.02

3.4±0.05

ZDF

3.3±0.04*

   

4.8±0.13*

5.0±0.24*

Body weight (g)

      

Lean

211±5

247±4

280±3

317±5

314±6

365±5

ZDF

252±7*

332±9*

395±7*

449±5*

486±7*

504±9*

  1. Body weight, HbA1c levels, and blood glucose levels are significantly increased in ZDF compared to Lean rats as measured in week 7 to week 17. * < 0.05 = different from controls (Lean) at the same stage.