Skip to main content

Table 3 Sister Chromatid Assay of Transfected Cell Lines: chromosome data

From: The C-terminal domain of the Bloom syndrome DNA helicase is essential for genomic stability

Cell Line

Mean # of

Mean#ofCs

Range of # of

Range of # of

Ring Cs to

Ring Cs to

 

Cs-Tet

+Tet

Cs

Cs

Total Cs -Tet

Total Cs +Tet

   

-Tet

+Tet

  

GFP

57

58

40-112

48-69

0/1116

0/1140

GFP-BLM

67

67

60-75

61-70

0/1340

0/1340

GFP-ΔN1

78

74

61-103

58-112

0/1560

0/1480

GFP-ΔN2

58

63

50-70

58-67

0/1116

0/1260

GFP-ΔN3

62

60

48-72

56-68

0/1240

0/1200

GFP-ΔN4

55

57

48-71

50-103

0/1100

0/1114

GFP-K695T

60

62

48-68

56-70

0/1200

0/1240

GFP-ΔH1

84

82

52-102

54-102

0/1680

0/1640

GFP-ΔC1

105

95

77-203

88-150

1/2100

7/1900

GFP-ΔC2

88

88

58-102

76-100

0/1760

3/1760

  1. The mean number of chromosomes (Cs) per metaphase is shown for each cell line. The range of the chromosome number is shown. The number of ring chromosomes found is reported as number per total chromosomes examined for each cell line. Cell lines were induced with 1 μg/ml Tet.