Figure 4

Immunofluorescence localization of β-dystroglycan and associated components in forebrain from dystrophic animal models. Shown are cryosections labeled with antibodies to laminin (LAM) (a-c), α-dystroglycan (α-DG) (d-f), β-dystroglycan (β-DG) (g-i), the carboxy-terminus of dystrophin (C-DYS) (j-l), and utrophin (UTR) (m-o). Forebrain specimens were taken from normal mice (a, d, g, j, m), mdx mice (b, e, h, k, n) and mdx-3cv mice (c, f, i, l, o). Bar = 40 μm.