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Figure 3 | BMC Cell Biology

Figure 3

From: Xanthurenic acid translocates proapoptotic Bcl-2 family proteins into mitochondria and impairs mitochondrial function

Figure 3

Western blot analysis of supernatant from rat liver mitochondria incubated for 1 h in the presence of xanthurenic acid for Bax, Bcl-xsand cytochrome c; (A-B) Western blot analysis of Bax and Bcl-xs: lane 1-control mitochondria; lanes 2–5: mitochondria incubated in the presence of xanthurenic acid at concentration 5; 10; 20; and 40 μM per mg of protein (A) Bax; (B) Bcl-xs, (C) release of cytochrome c from mitochondria in the presence of xanthurenic acid at the same concentrations as in (A-B).

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