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Figure 6 | BMC Cell Biology

Figure 6

From: Two Drosophila suppressors of cytokine signaling (SOCS) differentially regulate JAK and EGFR pathway activities

Figure 6

Socs44A deficiencies enhance argos misexpression phenotypes. (A) The engrailed-GAL4 driven misexpression of argos produces a range of phenotypes which were classified based on severity. The combination of en-GAL and Df(2)CA53 had no effect on venation. (B) In flies that were also heterozygous for Df(2)CA53, which removes the Socs44A locus, the distribution of phenotypes was significantly shifted to more severe classes as compared to animals heterozygous for Df(2)Drlrv18, an overlapping deficiency that does not remove Socs44A or for Sco, a chromosome wild-type for the 44A region.

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