3D-FISH on structurally preserved cell nuclei with paints for chromosome 1 (red) and chromosome 8 (green). For each cell type, two confocal sections of one nucleus are shown. Nuclear outlines were drawn after the DNA counterstain which was omitted to avoid obstruction of the territory signals. (a) Multipotent myeloid precursor. (b) Myeloblast. (c) Macrophage activated with LPS. (d) Proerythroblast. Scalebar 5 μm.