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Figure 3 | BMC Cell Biology

Figure 3

From: Dermal fibroblasts in Hutchinson-Gilford progeria syndrome with the lamin A G608G mutation have dysmorphic nuclei and are hypersensitive to heat stress

Figure 3

Comparison of lamin A/C localization with lamin B1, emerin and chromatin in dysmorphic nuclei of fibroblasts from the subject with HGPS. Upper panel shows micrographs of fibroblasts from the subject with HGPS labelled with anti-lamin A/C antibodies (a), anti-lamin B1 antibodies (b), the merged signal (c) and DAPI (d). Lower panel shows micrographs of fibroblasts from the same subject labelled with anti-lamin A/C antibodies (e), anti-emerin antibodies (f), the merged signal (g), and DAPI (h). Bar, 10 μm.

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