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Table 1 Alteration of integrin subunits and uPAR in pancreatic cancer cells in response to IL-1α

From: Interleukin-1α enhances the aggressive behavior of pancreatic cancer cells by regulating the α6β1-integrin and urokinase plasminogen activator receptor expression

Antigen IL-1α Mean fluorescence intensity
   BxPC-3 Capan-2 SW1990
α3integrin - 310 ± 18 350 ± 12 411 ± 14
  + 383 ± 34a 344 ± 18 399 ± 16
α5integrin - 40 ± 6 72 ± 9 60 ± 8
  + 44 ± 4 68 ± 8 61 ± 6
α6integrin - 520 ± 21 230 ± 11 441 ± 18
  + 833 ± 44a 344 ± 27a 612 ± 32a
αv integrin - 77 ± 8 61 ± 9 51 ± 8
  + 71 ± 7 65 ± 9 58 ± 6
β1integrin - 997 ± 42 814 ± 31 810 ± 33
  + 1229 ± 41a 1183 ± 22a 1322 ± 24a
uPA - 34 ± 3 42 ± 2 51 ± 5
  + 143 ± 10a 166 ± 13a 191 ± 9a
uPAR - 219 ± 17 299 ± 31 291 ± 18
  + 423 ± 26a 588 ± 21a 524 ± 19a
  1. IL-1α, interleukin-1α; uPA, urokinase plasminogen activator; uPAR, urokinase plasminogen activator receptor. All data are expressed as mean ± s.d. The p-values indicate statistical significance between data in controls and presence of IL-α. a p < 0.01.