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Table 1 Quantitative mutation suppression.

From: The OXR domain defines a conserved family of eukaryotic oxidation resistance proteins

Strain genotype Plasmid/insert Mutation frequencya Standard deviation Mutagenesis suppression
(% reduction of vector control)
mutM mutY pTrc99a vector only 9799 ± 2848 NAb
mutM mutY pTrc99a/OXR1 [21] 773 ± 324 * 90
mutM mutY pTrc99a/NCOA7 0.26 ± 0.22 * >99.9
mutM mutY pTrc99a/OXR2 domain of NCOA7 (657–942) 2635 ± 725 * 73
Wild type pTrc99a vector 0.31 ± 0.17 * NA
  1. aMutation frequency (Mutants/107 viable cells). Data represent the averages of at least 6 independent measurements.
  2. b Not Applicable.