Skip to main content
Figure 2 | BMC Cell Biology

Figure 2

From: Phosphatidylinositol 3-kinase signaling in proliferating cells maintains an anti-apoptotic transcriptional program mediated by inhibition of FOXO and non-canonical activation of NFκB transcription factors

Figure 2

Changes in gene expression resulting from PI 3-kinase inhibition. Proliferating T98G cells in serum-containing medium were treated with 50 μM LY294002 for 2, 4 or 8 hours. Microarray analyses at each timepoint were performed on 3 independent cultures compared to untreated controls. Data are presented as the number of genes that were significantly up-regulated and down-regulated at the specified time of treatment (Log2 > 0.9, p ≤ 0.01).

Back to article page

BMC Molecular and Cell Biology

ISSN: 2661-8850

Contact us