Figure 2
From: Identification of a subunit of NADH-dehydrogenase as a p49/STRAP-binding protein
Bioinformatics analysis of p49 sequence. Bioinformatics analysis of the sequence of human p49 protein shows that there are four classic nuclear localizing sequences (NLS's), three of them are in the N-terminal region. NLS1 & NLS2 are bipartite nuclear localization sequences. NLS3 has a pattern-7 motif, and NLS4 has a pattern-4 motif. Blue (residue K or R) indicates positively charged (basic) residues, red (residue D or E) indicates negatively charged (acidic) residues. The sections underlined in green are highly conserved across human, rat, and mouse.