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Table 1 Differentially expressed genes in cells with nuclear syndecan-1 (FLs1) versus cells with syndecan-1 lacking the NLS signal (NLSdel)

From: Molecular targets and signaling pathways regulated by nuclear translocation of syndecan-1

FLs1 vs NLSdel

Symbol

Gene name

FC

q

EFCAB6

EF-hand calcium binding domain 6

2.24

0.013

CCKAR

cholecystokinin A receptor

1.97

0.025

EGR1

early growth response 1

1.85

0.003

CDCP1

CUB domain containing protein 1

1.84

0.00

ZNF676

zinc finger protein 676

1.84

0.031

NEK11

NIMA (never in mitosis gene a- related kinase 11

1.77

0.001

SLC16A4

solute carrier family 16, member 4 (monocarboxylic acid transporter 5)

1.75

0.013

DOCK8

dedicator of cytokinesis 8

1.72

0.00

LMBRD2

LMBR1 domain containing 2

1.68

0.037

SNORA56

small nucleolar RNA, H/ACA box 56

1.67

0.015

LPCAT2

lysophosphatidylcholine acyltransferase 2

1.6

0.017

LSM14B

LSM14B, SCD6 homolog B (S. cerevisiae)

1.58

0.047

HBG1

hemoglobin, gamma A

1.57

0.01

SNORA13

small nucleolar RNA, H/ACA box 13

1.57

0.026

SNORD116–6

small nucleolar RNA, C/D box 116–6

1.57

0.00

CCDC88C

coiled-coil domain containing 88C

1.56

0.03

EHF

ets homologous factor

1.52

0.006

PMFBP1

polyamine modulated factor 1 binding protein 1

1.51

0.015

PLA2G5

phospholipase A2, group V

−1.59

0.002

CYP3A7

cytochrome P450, family 3, subfamily A, polypeptide 7

−1.6

0.001

  1. Differentially expressed genes identified by microarray analysis in fibrosarcoma cells with nuclear syndecan-1 (FLs1) versus syndecan-1 lacking the NLS signal (NLSdel). FC fold change, q false discovery rate