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Fig. 5 | BMC Molecular and Cell Biology

Fig. 5

From: Characterization and engineering of a DNA polymerase reveals a single amino-acid substitution in the fingers subdomain to increase strand-displacement activity of A-family prokaryotic DNA polymerases

Fig. 5

Cartoon representation of Geobacillus stearothermophilus polymerase I large fragment (PDB code 1XWL). Left showing the subdomains of the DNA polymerase large fragment: fingers (cyan), thumb (magenta) and palm (green). Right showing a close-up view of D422 residue (orange) located on the O1-helix and R433 residue (orange) located on the O2-helix and the distance measurement between them. The cartoon representation has been generated in PyMOL (The PyMol Molecular Graphics System, Version 2.0 Schrödinger, LLC)

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