Table 3 Paclitaxel and EMSO Combination Index (CI) against A2780 and A2780/T Cells
Combination type | Inhibitory rate | CI | Interaction type |
|---|---|---|---|
A2780+ PTX(0.05) | 4.7 | Â | Â |
A2780+ EMSO(50) | 1.6 | Â | Â |
A2780+ PTX(0.05) + EMSO(50) | 6.3 | 1.0 | Additive |
A2780+ PTX(0.25) | 29.1 | Â | Â |
A2780+ EMSO(100) | 9.2 | Â | Â |
A2780+ PTX(0.25) + EMSO(100) | 38.3 | 1.0 | Additive |
A2780+ PTX(1.25) | 72.3 | Â | Â |
A2780+ EMSO(130) | 44.2 | Â | Â |
A2780+ PTX(1.25) + EMSO(130) | 95.3 | 0.94 | Synergistic |
A2780/T+ PTX(0.04) | 0.7 | Â | Â |
A2780/T+ EMSO(50) | 1.2 | Â | Â |
A2780/T+ PTX(0.04) + EMSO(50) | 2.0 | 1.0 | Additive |
A2780/T + PTX(0.90) | 1.6 |  |  |
A2780/T+ EMSO(100) | 2.7 | Â | Â |
A2780/T + PTX(0.90) + EMSO(100) | 4.3 | 1.0 | Additive |
A2780/T + PTX(5.0) | 24.3 |  |  |
A2780/T+ EMSO(150) | 43.9 | Â | Â |
A2780/T + PTX(5.0) + EMSO(150) | 85.4 | 0.91 | Synergistic |