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Fig. 6 | BMC Molecular and Cell Biology

Fig. 6

From: LncRNA MEG3 influences the proliferation and apoptosis of psoriasis epidermal cells by targeting miR-21/caspase-8

Fig. 6

LncRNA MEG3 affected the proliferation and apoptosis of Act-HaCaT and Act-HHEK by regulating miR-21 expression and further influencing caspase-8. a The proliferation of Act-HaCaT and Act-HHEK was measured by MTT assay after transfection with miR-21 inhibitor+sh-NC, miR-21 inhibitor+sh-caspase-8, and pcDNA-MEG3 + sh-caspase-8, respectively. b The proliferation of Act-HaCaT and Act-HHEK was measured by colony formation assay after transfection with miR-21 inhibitor+sh-NC, miR-21 inhibitor+sh-caspase-8, and pcDNA-MEG3 + sh-caspase-8, respectively. c The apoptosis ratio of Act-HaCaT and Act-HHEK was measured after transfection with miR-21 inhibitor+sh-NC, miR-21 inhibitor+sh-caspase-8, and pcDNA-MEG3 + sh-caspase-8, respectively. d The mRNA expression of caspase-8, Bax, and Bcl-2 in Act-HaCaT and Act-HHEK after transfection with miR-21 inhibitor+sh-NC, miR-21 inhibitor+sh-caspase-8, and pcDNA-MEG3 + sh-caspase-8, respectively. All the results were shown as mean ± SD (n = 3), and the experiments were repeated three times

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