Fig. 6

the effect of miR-503 on MALAT1 modulate the function of NPC NPCs were co-transfected with miR-503 mimics or inhibitor and OV-MALAT1 under IL-1β stimulation; (a) and (b) The cell viability was determined using CCK8 assays and cells counting. c-d The cell apoptosis was determined using Annexin V/PI stain. e-g The protein levels of Collagen II and Aggrecan were determined using Immunoblotting assays. d The protein levels of the MAPK pathway were determined using Immunoblotting assays. The data are presented as mean ± SD of three independent experiments. *P < 0.05, compared to control group; ##P < 0.01, compared to IL-1β + si-circSEMA4B group