Fig. 2
From: Diazoxide affects mitochondrial bioenergetics by the opening of mKATP channel on submicromolar scale
Absorbance assay of the effect of mKATP-channel ligands on K+ transport. a – typical pattern in standard incubation medium with DZ added at 0, 0.5 and 100 μM (as indicated); Mg∙ATP (black line); Mg∙ATP and DZ at 30 and 100 μM (grey lines); Mg∙ATP, 30 μM DZ, glibenclamide (dotted line) or 5-HD (light grey); b, c − absorbance differences obtained in K+- (b) and Na+-(c) based media after the additions of DZ in the absence and the presence of Mg∙ATP (b, c); after the additions of glibenclamide and 5-HD in the presence of Mg∙ATP, 30 μM DZ (b). The values obtained in control in the presence of MgATP were subtracted. M ± m, n = 4; b, c: * - P < 0.05 vs. 0 DZ; ** - P < 0.01 vs. 30 μM DZ; # - P < 0.05 vs. MgATP, 0 DZ; ## - P < 0.01 vs. MgATP, 30 μM DZ