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Fig. 4 | BMC Molecular and Cell Biology

Fig. 4

From: Probing contacts of inhibitor locked in transition states in the catalytic triad of DENV2 type serine protease and its mutants by 1H, 19F and 15 N NMR spectroscopy

Fig. 4

Schematic representation of possible tautomer forms of the NS2B:NS3pro active site inhibitors (I, II). Schematic representation of possible tautomer forms of the NS2B:NS3pro active site with boronic acid inhibitor (I): Bz-Nle-Lys-Arg-Arg-B(OH)2 [1]– [5] and with tfk inhibitor (II): di-fluoro-Bz-Nle-Lys-Arg-Arg-CF3-ketone [6]

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BMC Molecular and Cell Biology

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