Skip to main content

Table 2 Docking results and hypothesis test for each protein wild and mutant docked to cellobiose (affinity score average for poses 1–3). For affinity scores, lower values represent more affinity. Affinity score variation (ΔAS)

From: Glutantβase: a database for improving the rational design of glucose-tolerant β-glucosidases

Substrate (cellobiose)
Mutation Affinity score (wild; 1–3) Affinity score (mutant; 1–3) Variation (ΔAS) ΔAS expected p-value status
A404V −4.6347 −4.6057 0.0290 ΔAS < 0 1 X
E96K −4.8509 −4.8341 0.0168 ΔAS < 0 1 X
H184F −4.7473 −4.7009 0.0463 ΔAS < 0 1 X
H228T −4.4806 −4.6509 −0.1703 ΔAS < 0 <  2.2e-16
L441F −4.8407 −4.8239 0.0169 ΔAS < 0 0.9031 X
V174C −5.1818 −5.1669 0.0149 ΔAS < 0 1 X